MotifPO3F1.H12INVITRO.1.PS.A
Gene (human)POU3F1
(GeneCards)
Gene synonyms (human)OCT6, OTF6
Gene (mouse)Pou3f1
Gene synonyms (mouse)Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length20
ConsensusnnhWKRATTATKCAWRWdnn
GC content26.08%
Information content (bits; total / per base)15.564 / 0.778
Data sourcesChIP-Seq + HT-SELEX
Aligned words7886

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (39) 0.742 0.943 0.592 0.92 0.736 0.929 2.42 4.261 72.509 321.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.971 0.955 0.935 0.911 0.839 0.825
best 0.996 0.993 0.991 0.987 0.958 0.951
Methyl HT-SELEX, 1 experiments median 0.961 0.938 0.928 0.897 0.876 0.842
best 0.961 0.938 0.928 0.897 0.876 0.842
Non-Methyl HT-SELEX, 3 experiments median 0.981 0.972 0.942 0.925 0.802 0.809
best 0.996 0.993 0.991 0.987 0.958 0.951
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.1
HGNCHGNC:9214
MGIMGI:101896
EntrezGene (human)GeneID:5453
(SSTAR profile)
EntrezGene (mouse)GeneID:18991
(SSTAR profile)
UniProt ID (human)PO3F1_HUMAN
UniProt ID (mouse)PO3F1_MOUSE
UniProt AC (human)Q03052
(TFClass)
UniProt AC (mouse)P21952
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012179.752033.751447.752224.75
022660.752327.751262.751634.75
034279.01852.0638.01117.0
042019.0565.0285.05017.0
051641.0123.02157.03965.0
065348.0551.01659.0328.0
076206.0368.085.01227.0
081870.014.0185.05817.0
091102.050.05.06729.0
107871.01.02.012.0
1119.018.036.07813.0
121.03.04114.03768.0
13139.07403.052.0292.0
146144.06.026.01710.0
152599.046.051.05190.0
163961.071.02899.0955.0
173600.0694.0260.03332.0
181535.0598.02733.03020.0
192233.01328.01613.02712.0
201929.251357.252214.252385.25
PFM
ACGT
010.2760.2580.1840.282
020.3370.2950.160.207
030.5430.2350.0810.142
040.2560.0720.0360.636
050.2080.0160.2740.503
060.6780.070.210.042
070.7870.0470.0110.156
080.2370.0020.0230.738
090.140.0060.0010.853
100.9980.00.00.002
110.0020.0020.0050.991
120.00.00.5220.478
130.0180.9390.0070.037
140.7790.0010.0030.217
150.330.0060.0060.658
160.5020.0090.3680.121
170.4570.0880.0330.423
180.1950.0760.3470.383
190.2830.1680.2050.344
200.2450.1720.2810.302
PWM
ACGT
010.10.031-0.3080.121
020.30.166-0.445-0.187
030.774-0.062-1.126-0.567
040.024-1.247-1.9270.933
05-0.183-2.7570.090.698
060.997-1.272-0.172-1.788
071.146-1.674-3.119-0.474
08-0.053-4.8-2.3551.081
09-0.581-3.632-5.6081.227
101.384-6.411-6.142-4.931
11-4.532-4.58-3.9441.376
12-6.411-5.9310.7350.647
13-2.6371.322-3.594-1.903
141.136-5.478-4.247-0.142
150.276-3.711-3.6130.967
160.697-3.2940.385-0.724
170.602-1.042-2.0180.524
18-0.25-1.190.3260.426
190.124-0.395-0.20.319
20-0.022-0.3730.1160.19
Standard thresholds
P-value Threshold
0.001 1.95851
0.0005 3.38266
0.0001 6.28031