MotifPO3F1.H12INVITRO.0.P.B
Gene (human)POU3F1
(GeneCards)
Gene synonyms (human)OCT6, OTF6
Gene (mouse)Pou3f1
Gene synonyms (mouse)Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length15
ConsensusdhATGMAWATKhvnn
GC content33.53%
Information content (bits; total / per base)10.432 / 0.695
Data sourcesChIP-Seq
Aligned words996

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (39) 0.776 0.875 0.674 0.8 0.743 0.826 2.294 3.095 44.222 166.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.987 0.978 0.96 0.946 0.863 0.857
best 0.997 0.995 0.991 0.987 0.958 0.951
Methyl HT-SELEX, 1 experiments median 0.989 0.98 0.971 0.959 0.909 0.894
best 0.989 0.98 0.971 0.959 0.909 0.894
Non-Methyl HT-SELEX, 3 experiments median 0.984 0.976 0.948 0.933 0.818 0.821
best 0.997 0.995 0.991 0.987 0.958 0.951
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.1
HGNCHGNC:9214
MGIMGI:101896
EntrezGene (human)GeneID:5453
(SSTAR profile)
EntrezGene (mouse)GeneID:18991
(SSTAR profile)
UniProt ID (human)PO3F1_HUMAN
UniProt ID (mouse)PO3F1_MOUSE
UniProt AC (human)Q03052
(TFClass)
UniProt AC (mouse)P21952
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01237.0100.0230.0429.0
02193.0466.085.0252.0
03871.064.019.042.0
0419.02.025.0950.0
0532.033.0871.060.0
06213.0612.075.096.0
07730.020.05.0241.0
08575.011.079.0331.0
09937.024.022.013.0
10113.016.052.0815.0
1148.045.0447.0456.0
12373.0284.0158.0181.0
13519.0157.0227.093.0
14294.0154.0221.0327.0
15215.0203.0302.0276.0
PFM
ACGT
010.2380.10.2310.431
020.1940.4680.0850.253
030.8740.0640.0190.042
040.0190.0020.0250.954
050.0320.0330.8740.06
060.2140.6140.0750.096
070.7330.020.0050.242
080.5770.0110.0790.332
090.9410.0240.0220.013
100.1130.0160.0520.818
110.0480.0450.4490.458
120.3740.2850.1590.182
130.5210.1580.2280.093
140.2950.1550.2220.328
150.2160.2040.3030.277
PWM
ACGT
01-0.049-0.902-0.0790.541
02-0.2530.624-1.0620.012
031.247-1.339-2.493-1.746
04-2.493-4.209-2.2391.334
05-2.006-1.9771.247-1.402
06-0.1550.895-1.184-0.942
071.071-2.446-3.618-0.032
080.833-2.981-1.1330.283
091.32-2.277-2.358-2.835
10-0.782-2.649-1.541.181
11-1.618-1.680.5820.602
120.4020.131-0.451-0.316
130.731-0.457-0.092-0.973
140.165-0.476-0.1180.271
15-0.146-0.2030.1920.102
Standard thresholds
P-value Threshold
0.001 4.61991
0.0005 5.47916
0.0001 7.24346