MotifPO3F1.H12CORE.1.PS.A
Gene (human)POU3F1
(GeneCards)
Gene synonyms (human)OCT6, OTF6
Gene (mouse)Pou3f1
Gene synonyms (mouse)Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length15
ConsensusdhhYATGMATAWKSM
GC content31.86%
Information content (bits; total / per base)15.371 / 1.025
Data sourcesChIP-Seq + HT-SELEX
Aligned words868

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (39) 0.747 0.964 0.63 0.952 0.765 0.957 2.337 6.354 78.337 357.201

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.947 0.921 0.903 0.87 0.816 0.791
best 0.997 0.995 0.985 0.981 0.933 0.924
Methyl HT-SELEX, 1 experiments median 0.915 0.873 0.879 0.83 0.831 0.782
best 0.915 0.873 0.879 0.83 0.831 0.782
Non-Methyl HT-SELEX, 3 experiments median 0.979 0.97 0.928 0.91 0.801 0.8
best 0.997 0.995 0.985 0.981 0.933 0.924
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.1
HGNCHGNC:9214
MGIMGI:101896
EntrezGene (human)GeneID:5453
(SSTAR profile)
EntrezGene (mouse)GeneID:18991
(SSTAR profile)
UniProt ID (human)PO3F1_HUMAN
UniProt ID (mouse)PO3F1_MOUSE
UniProt AC (human)Q03052
(TFClass)
UniProt AC (mouse)P21952
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01299.0120.0171.0278.0
0298.0474.075.0221.0
03281.089.068.0430.0
0489.0662.010.0107.0
05828.04.06.030.0
066.02.03.0857.0
0788.05.0765.010.0
08492.0360.05.011.0
09852.06.03.07.0
1027.04.01.0836.0
11797.08.08.055.0
12385.014.07.0462.0
1387.010.0247.0524.0
147.0386.0290.0185.0
15513.0325.020.010.0
PFM
ACGT
010.3440.1380.1970.32
020.1130.5460.0860.255
030.3240.1030.0780.495
040.1030.7630.0120.123
050.9540.0050.0070.035
060.0070.0020.0030.987
070.1010.0060.8810.012
080.5670.4150.0060.013
090.9820.0070.0030.008
100.0310.0050.0010.963
110.9180.0090.0090.063
120.4440.0160.0080.532
130.10.0120.2850.604
140.0080.4450.3340.213
150.5910.3740.0230.012
PWM
ACGT
010.318-0.586-0.2360.246
02-0.7860.777-1.0480.018
030.257-0.88-1.1440.68
04-0.881.11-2.929-0.699
051.333-3.649-3.348-1.932
06-3.348-4.082-3.8421.368
07-0.891-3.4871.254-2.929
080.8140.503-3.487-2.847
091.362-3.348-3.842-3.225
10-2.031-3.649-4.3981.343
111.295-3.116-3.116-1.35
120.57-2.635-3.2250.752
13-0.902-2.9290.1290.877
14-3.2250.5730.288-0.158
150.8560.401-2.311-2.929
Standard thresholds
P-value Threshold
0.001 2.55031
0.0005 3.80046
0.0001 6.42476