Motif | PO3F1.H12CORE.1.PS.A |
Gene (human) | POU3F1 (GeneCards) |
Gene synonyms (human) | OCT6, OTF6 |
Gene (mouse) | Pou3f1 |
Gene synonyms (mouse) | Oct6, Otf-6, Otf6, Scip |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif | PO3F1.H12CORE.1.PS.A |
Gene (human) | POU3F1 (GeneCards) |
Gene synonyms (human) | OCT6, OTF6 |
Gene (mouse) | Pou3f1 |
Gene synonyms (mouse) | Oct6, Otf-6, Otf6, Scip |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif length | 15 |
Consensus | dhhYATGMATAWKSM |
GC content | 31.86% |
Information content (bits; total / per base) | 15.371 / 1.025 |
Data sources | ChIP-Seq + HT-SELEX |
Aligned words | 868 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 6 (39) | 0.747 | 0.964 | 0.63 | 0.952 | 0.765 | 0.957 | 2.337 | 6.354 | 78.337 | 357.201 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.947 | 0.921 | 0.903 | 0.87 | 0.816 | 0.791 |
best | 0.997 | 0.995 | 0.985 | 0.981 | 0.933 | 0.924 | |
Methyl HT-SELEX, 1 experiments | median | 0.915 | 0.873 | 0.879 | 0.83 | 0.831 | 0.782 |
best | 0.915 | 0.873 | 0.879 | 0.83 | 0.831 | 0.782 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.979 | 0.97 | 0.928 | 0.91 | 0.801 | 0.8 |
best | 0.997 | 0.995 | 0.985 | 0.981 | 0.933 | 0.924 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU3 {3.1.10.3} (TFClass) |
TFClass ID | TFClass: 3.1.10.3.1 |
HGNC | HGNC:9214 |
MGI | MGI:101896 |
EntrezGene (human) | GeneID:5453 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18991 (SSTAR profile) |
UniProt ID (human) | PO3F1_HUMAN |
UniProt ID (mouse) | PO3F1_MOUSE |
UniProt AC (human) | Q03052 (TFClass) |
UniProt AC (mouse) | P21952 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 6 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | PO3F1.H12CORE.1.PS.A.pcm |
PWM | PO3F1.H12CORE.1.PS.A.pwm |
PFM | PO3F1.H12CORE.1.PS.A.pfm |
Alignment | PO3F1.H12CORE.1.PS.A.words.tsv |
Threshold to P-value map | PO3F1.H12CORE.1.PS.A.thr |
Motif in other formats | |
JASPAR format | PO3F1.H12CORE.1.PS.A_jaspar_format.txt |
MEME format | PO3F1.H12CORE.1.PS.A_meme_format.meme |
Transfac format | PO3F1.H12CORE.1.PS.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 299.0 | 120.0 | 171.0 | 278.0 |
02 | 98.0 | 474.0 | 75.0 | 221.0 |
03 | 281.0 | 89.0 | 68.0 | 430.0 |
04 | 89.0 | 662.0 | 10.0 | 107.0 |
05 | 828.0 | 4.0 | 6.0 | 30.0 |
06 | 6.0 | 2.0 | 3.0 | 857.0 |
07 | 88.0 | 5.0 | 765.0 | 10.0 |
08 | 492.0 | 360.0 | 5.0 | 11.0 |
09 | 852.0 | 6.0 | 3.0 | 7.0 |
10 | 27.0 | 4.0 | 1.0 | 836.0 |
11 | 797.0 | 8.0 | 8.0 | 55.0 |
12 | 385.0 | 14.0 | 7.0 | 462.0 |
13 | 87.0 | 10.0 | 247.0 | 524.0 |
14 | 7.0 | 386.0 | 290.0 | 185.0 |
15 | 513.0 | 325.0 | 20.0 | 10.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.344 | 0.138 | 0.197 | 0.32 |
02 | 0.113 | 0.546 | 0.086 | 0.255 |
03 | 0.324 | 0.103 | 0.078 | 0.495 |
04 | 0.103 | 0.763 | 0.012 | 0.123 |
05 | 0.954 | 0.005 | 0.007 | 0.035 |
06 | 0.007 | 0.002 | 0.003 | 0.987 |
07 | 0.101 | 0.006 | 0.881 | 0.012 |
08 | 0.567 | 0.415 | 0.006 | 0.013 |
09 | 0.982 | 0.007 | 0.003 | 0.008 |
10 | 0.031 | 0.005 | 0.001 | 0.963 |
11 | 0.918 | 0.009 | 0.009 | 0.063 |
12 | 0.444 | 0.016 | 0.008 | 0.532 |
13 | 0.1 | 0.012 | 0.285 | 0.604 |
14 | 0.008 | 0.445 | 0.334 | 0.213 |
15 | 0.591 | 0.374 | 0.023 | 0.012 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.318 | -0.586 | -0.236 | 0.246 |
02 | -0.786 | 0.777 | -1.048 | 0.018 |
03 | 0.257 | -0.88 | -1.144 | 0.68 |
04 | -0.88 | 1.11 | -2.929 | -0.699 |
05 | 1.333 | -3.649 | -3.348 | -1.932 |
06 | -3.348 | -4.082 | -3.842 | 1.368 |
07 | -0.891 | -3.487 | 1.254 | -2.929 |
08 | 0.814 | 0.503 | -3.487 | -2.847 |
09 | 1.362 | -3.348 | -3.842 | -3.225 |
10 | -2.031 | -3.649 | -4.398 | 1.343 |
11 | 1.295 | -3.116 | -3.116 | -1.35 |
12 | 0.57 | -2.635 | -3.225 | 0.752 |
13 | -0.902 | -2.929 | 0.129 | 0.877 |
14 | -3.225 | 0.573 | 0.288 | -0.158 |
15 | 0.856 | 0.401 | -2.311 | -2.929 |
P-value | Threshold |
---|---|
0.001 | 2.55031 |
0.0005 | 3.80046 |
0.0001 | 6.42476 |