PO2F3.H12RSNP.0.PS.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO2F3.H12RSNP.0.PS.D
Gene (human)	POU2F3 (GeneCards)
Gene synonyms (human)	OTF11, PLA1
Gene (mouse)	Pou2f3
Gene synonyms (mouse)	Epoc1, Oct11, Otf-11, Otf11
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	13
Consensus	dbGCAAATTWvnn
GC content	35.74%
Information content (bits; total / per base)	13.392 / 1.03
Data sources	ChIP-Seq + HT-SELEX
Aligned words	7441

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (6)	0.811	0.83	0.713	0.735	0.74	0.762	2.34	2.452	109.297	128.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.998	0.996	0.995	0.993	0.987	0.982
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.996	0.994	0.988	0.983

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU2 {3.1.10.2} (TFClass)
TFClass ID	TFClass: 3.1.10.2.3
HGNC	HGNC:19864
MGI	MGI:102565
EntrezGene (human)	GeneID:25833 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	PO2F3_HUMAN
UniProt ID (mouse)	PO2F3_MOUSE
UniProt AC (human)	Q9UKI9 (TFClass)
UniProt AC (mouse)	P31362 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	PO2F3.H12RSNP.0.PS.D.pcm
PWM	PO2F3.H12RSNP.0.PS.D.pwm
PFM	PO2F3.H12RSNP.0.PS.D.pfm
Alignment	PO2F3.H12RSNP.0.PS.D.words.tsv
Threshold to P-value map	PO2F3.H12RSNP.0.PS.D.thr
Motif in other formats
JASPAR format	PO2F3.H12RSNP.0.PS.D_jaspar_format.txt
MEME format	PO2F3.H12RSNP.0.PS.D_meme_format.meme
Transfac format	PO2F3.H12RSNP.0.PS.D_transfac_format.txt
Homer format	PO2F3.H12RSNP.0.PS.D_homer_format_0.001.txt PO2F3.H12RSNP.0.PS.D_homer_format_0.0005.txt PO2F3.H12RSNP.0.PS.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	4030.25	1094.25	1175.25	1141.25
02	1094.5	1153.5	1180.5	4012.5
03	39.0	35.0	7291.0	76.0
04	21.0	7178.0	59.0	183.0
05	4542.0	1.0	1.0	2897.0
06	7330.0	2.0	28.0	81.0
07	7441.0	0.0	0.0	0.0
08	0.0	2.0	6.0	7433.0
09	26.0	336.0	736.0	6343.0
10	5056.0	752.0	92.0	1541.0
11	1384.0	1380.0	3912.0	765.0
12	871.75	2191.75	2177.75	2199.75
13	1317.5	2303.5	1484.5	2335.5

PFM

	A	C	G	T
01	0.542	0.147	0.158	0.153
02	0.147	0.155	0.159	0.539
03	0.005	0.005	0.98	0.01
04	0.003	0.965	0.008	0.025
05	0.61	0.0	0.0	0.389
06	0.985	0.0	0.004	0.011
07	1.0	0.0	0.0	0.0
08	0.0	0.0	0.001	0.999
09	0.003	0.045	0.099	0.852
10	0.679	0.101	0.012	0.207
11	0.186	0.185	0.526	0.103
12	0.117	0.295	0.293	0.296
13	0.177	0.31	0.2	0.314

PWM

	A	C	G	T
01	0.772	-0.53	-0.459	-0.488
02	-0.53	-0.477	-0.454	0.768
03	-3.811	-3.913	1.365	-3.17
04	-4.384	1.349	-3.415	-2.308
05	0.892	-6.358	-6.358	0.443
06	1.37	-6.088	-4.121	-3.108
07	1.385	-6.728	-6.728	-6.728
08	-6.728	-6.088	-5.422	1.384
09	-4.189	-1.706	-0.925	1.226
10	0.999	-0.904	-2.984	-0.188
11	-0.295	-0.298	0.743	-0.887
12	-0.757	0.164	0.157	0.167
13	-0.344	0.213	-0.225	0.227

Standard thresholds

P-value	Threshold
0.001	2.77991
0.0005	4.16071
0.0001	7.103695