PO2F3.H12INVIVO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO2F3.H12INVIVO.1.S.C
Gene (human)	POU2F3 (GeneCards)
Gene synonyms (human)	OTF11, PLA1
Gene (mouse)	Pou2f3
Gene synonyms (mouse)	Epoc1, Oct11, Otf-11, Otf11
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	19
Consensus	hdhWTWWGCTAATTWGbnn
GC content	32.99%
Information content (bits; total / per base)	18.37 / 0.967
Data sources	HT-SELEX
Aligned words	574

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (6)	0.787	0.801	0.68	0.694	0.74	0.754	2.442	2.489	100.959	116.004

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.99	0.985	0.968	0.957	0.922	0.903
Non-Methyl HT-SELEX, 2 experiments	best	0.992	0.988	0.971	0.961	0.924	0.907

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU2 {3.1.10.2} (TFClass)
TFClass ID	TFClass: 3.1.10.2.3
HGNC	HGNC:19864
MGI	MGI:102565
EntrezGene (human)	GeneID:25833 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	PO2F3_HUMAN
UniProt ID (mouse)	PO2F3_MOUSE
UniProt AC (human)	Q9UKI9 (TFClass)
UniProt AC (mouse)	P31362 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	PO2F3.H12INVIVO.1.S.C.pcm
PWM	PO2F3.H12INVIVO.1.S.C.pwm
PFM	PO2F3.H12INVIVO.1.S.C.pfm
Alignment	PO2F3.H12INVIVO.1.S.C.words.tsv
Threshold to P-value map	PO2F3.H12INVIVO.1.S.C.thr
Motif in other formats
JASPAR format	PO2F3.H12INVIVO.1.S.C_jaspar_format.txt
MEME format	PO2F3.H12INVIVO.1.S.C_meme_format.meme
Transfac format	PO2F3.H12INVIVO.1.S.C_transfac_format.txt
Homer format	PO2F3.H12INVIVO.1.S.C_homer_format_0.001.txt PO2F3.H12INVIVO.1.S.C_homer_format_0.0005.txt PO2F3.H12INVIVO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	167.75	102.75	75.75	227.75
02	256.75	28.75	209.75	78.75
03	295.0	123.0	77.0	79.0
04	282.0	12.0	72.0	208.0
05	20.0	36.0	18.0	500.0
06	457.0	15.0	41.0	61.0
07	61.0	27.0	42.0	444.0
08	26.0	47.0	491.0	10.0
09	2.0	569.0	2.0	1.0
10	255.0	0.0	0.0	319.0
11	565.0	1.0	1.0	7.0
12	574.0	0.0	0.0	0.0
13	0.0	0.0	0.0	574.0
14	4.0	9.0	24.0	537.0
15	372.0	15.0	0.0	187.0
16	38.0	31.0	485.0	20.0
17	46.0	313.0	109.0	106.0
18	115.75	205.75	103.75	148.75
19	119.5	201.5	109.5	143.5

PFM

	A	C	G	T
01	0.292	0.179	0.132	0.397
02	0.447	0.05	0.365	0.137
03	0.514	0.214	0.134	0.138
04	0.491	0.021	0.125	0.362
05	0.035	0.063	0.031	0.871
06	0.796	0.026	0.071	0.106
07	0.106	0.047	0.073	0.774
08	0.045	0.082	0.855	0.017
09	0.003	0.991	0.003	0.002
10	0.444	0.0	0.0	0.556
11	0.984	0.002	0.002	0.012
12	1.0	0.0	0.0	0.0
13	0.0	0.0	0.0	1.0
14	0.007	0.016	0.042	0.936
15	0.648	0.026	0.0	0.326
16	0.066	0.054	0.845	0.035
17	0.08	0.545	0.19	0.185
18	0.202	0.358	0.181	0.259
19	0.208	0.351	0.191	0.25

PWM

	A	C	G	T
01	0.155	-0.33	-0.629	0.458
02	0.577	-1.565	0.376	-0.591
03	0.715	-0.152	-0.613	-0.588
04	0.67	-2.368	-0.679	0.368
05	-1.905	-1.351	-2.002	1.24
06	1.151	-2.169	-1.226	-0.841
07	-0.841	-1.624	-1.203	1.122
08	-1.66	-1.094	1.222	-2.527
09	-3.7	1.369	-3.7	-4.026
10	0.57	-4.515	-4.515	0.793
11	1.362	-4.026	-4.026	-2.827
12	1.378	-4.515	-4.515	-4.515
13	-4.515	-4.515	-4.515	1.378
14	-3.257	-2.618	-1.735	1.312
15	0.946	-2.169	-4.515	0.262
16	-1.299	-1.493	1.21	-1.905
17	-1.115	0.774	-0.272	-0.299
18	-0.212	0.357	-0.32	0.036
19	-0.181	0.336	-0.267	0.0

Standard thresholds

P-value	Threshold
0.001	1.12216
0.0005	2.52651
0.0001	5.46611