MotifPO2F2.H12RSNP.2.S.D
Gene (human)POU2F2
(GeneCards)
Gene synonyms (human)OCT2, OTF2
Gene (mouse)Pou2f2
Gene synonyms (mouse)Oct2, Otf2
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
D
Motif length13
ConsensusdYWTGCATATKhh
GC content26.8%
Information content (bits; total / per base)13.638 / 1.049
Data sourcesHT-SELEX
Aligned words6029

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (39) 0.74 0.867 0.642 0.802 0.76 0.903 3.101 4.837 183.678 316.244

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 7 experiments median 0.985 0.976 0.857 0.86 0.686 0.72
best 0.995 0.993 0.984 0.978 0.942 0.923
Methyl HT-SELEX, 2 experiments median 0.915 0.9 0.833 0.826 0.769 0.769
best 0.987 0.98 0.974 0.961 0.942 0.923
Non-Methyl HT-SELEX, 5 experiments median 0.985 0.976 0.857 0.86 0.686 0.72
best 0.995 0.993 0.984 0.978 0.89 0.891
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU2 {3.1.10.2} (TFClass)
TFClass IDTFClass: 3.1.10.2.2
HGNCHGNC:9213
MGIMGI:101897
EntrezGene (human)GeneID:5452
(SSTAR profile)
EntrezGene (mouse)GeneID:18987
(SSTAR profile)
UniProt ID (human)PO2F2_HUMAN
UniProt ID (mouse)PO2F2_MOUSE
UniProt AC (human)P09086
(TFClass)
UniProt AC (mouse)Q00196
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 2
PCM
ACGT
013157.5713.5818.51339.5
02800.01005.0467.03757.0
032465.0321.0349.02894.0
04285.0159.062.05523.0
0517.00.06012.00.0
062061.03968.00.00.0
076028.00.00.01.0
08198.00.00.05831.0
096029.00.00.00.0
10901.0273.0103.04752.0
11500.0321.01024.04184.0
12735.52906.5481.51905.5
132274.751024.75998.751730.75
PFM
ACGT
010.5240.1180.1360.222
020.1330.1670.0770.623
030.4090.0530.0580.48
040.0470.0260.010.916
050.0030.00.9970.0
060.3420.6580.00.0
071.00.00.00.0
080.0330.00.00.967
091.00.00.00.0
100.1490.0450.0170.788
110.0830.0530.170.694
120.1220.4820.080.316
130.3770.170.1660.287
PWM
ACGT
010.739-0.746-0.609-0.118
02-0.632-0.405-1.1690.912
030.491-1.541-1.4580.652
04-1.659-2.237-3.1581.298
05-4.366-6.5421.382-6.542
060.3130.967-6.542-6.542
071.385-6.542-6.542-6.164
08-2.02-6.542-6.5421.352
091.385-6.542-6.542-6.542
10-0.514-1.702-2.6641.147
11-1.101-1.541-0.3861.02
12-0.7160.656-1.1380.234
130.411-0.385-0.4110.138
Standard thresholds
P-value Threshold
0.001 2.75791
0.0005 4.278915
0.0001 7.054865