PO2F2.H12INVITRO.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO2F2.H12INVITRO.2.S.B
Gene (human)	POU2F2 (GeneCards)
Gene synonyms (human)	OCT2, OTF2
Gene (mouse)	Pou2f2
Gene synonyms (mouse)	Oct2, Otf2
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	13
Consensus	dYWTGCATATKhh
GC content	26.8%
Information content (bits; total / per base)	13.638 / 1.049
Data sources	HT-SELEX
Aligned words	6029

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	6 (39)	0.74	0.867	0.642	0.802	0.76	0.903	3.101	4.837	183.678	316.244

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 7 experiments	median	0.985	0.976	0.857	0.86	0.686	0.72
Overall, 7 experiments	best	0.995	0.993	0.984	0.978	0.942	0.923
Methyl HT-SELEX, 2 experiments	median	0.915	0.9	0.833	0.826	0.769	0.769
Methyl HT-SELEX, 2 experiments	best	0.987	0.98	0.974	0.961	0.942	0.923
Non-Methyl HT-SELEX, 5 experiments	median	0.985	0.976	0.857	0.86	0.686	0.72
Non-Methyl HT-SELEX, 5 experiments	best	0.995	0.993	0.984	0.978	0.89	0.891

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU2 {3.1.10.2} (TFClass)
TFClass ID	TFClass: 3.1.10.2.2
HGNC	HGNC:9213
MGI	MGI:101897
EntrezGene (human)	GeneID:5452 (SSTAR profile)
EntrezGene (mouse)	GeneID:18987 (SSTAR profile)
UniProt ID (human)	PO2F2_HUMAN
UniProt ID (mouse)	PO2F2_MOUSE
UniProt AC (human)	P09086 (TFClass)
UniProt AC (mouse)	Q00196 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	6 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	2

PCM	PO2F2.H12INVITRO.2.S.B.pcm
PWM	PO2F2.H12INVITRO.2.S.B.pwm
PFM	PO2F2.H12INVITRO.2.S.B.pfm
Alignment	PO2F2.H12INVITRO.2.S.B.words.tsv
Threshold to P-value map	PO2F2.H12INVITRO.2.S.B.thr
Motif in other formats
JASPAR format	PO2F2.H12INVITRO.2.S.B_jaspar_format.txt
MEME format	PO2F2.H12INVITRO.2.S.B_meme_format.meme
Transfac format	PO2F2.H12INVITRO.2.S.B_transfac_format.txt
Homer format	PO2F2.H12INVITRO.2.S.B_homer_format_0.001.txt PO2F2.H12INVITRO.2.S.B_homer_format_0.0005.txt PO2F2.H12INVITRO.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3157.5	713.5	818.5	1339.5
02	800.0	1005.0	467.0	3757.0
03	2465.0	321.0	349.0	2894.0
04	285.0	159.0	62.0	5523.0
05	17.0	0.0	6012.0	0.0
06	2061.0	3968.0	0.0	0.0
07	6028.0	0.0	0.0	1.0
08	198.0	0.0	0.0	5831.0
09	6029.0	0.0	0.0	0.0
10	901.0	273.0	103.0	4752.0
11	500.0	321.0	1024.0	4184.0
12	735.5	2906.5	481.5	1905.5
13	2274.75	1024.75	998.75	1730.75

PFM

	A	C	G	T
01	0.524	0.118	0.136	0.222
02	0.133	0.167	0.077	0.623
03	0.409	0.053	0.058	0.48
04	0.047	0.026	0.01	0.916
05	0.003	0.0	0.997	0.0
06	0.342	0.658	0.0	0.0
07	1.0	0.0	0.0	0.0
08	0.033	0.0	0.0	0.967
09	1.0	0.0	0.0	0.0
10	0.149	0.045	0.017	0.788
11	0.083	0.053	0.17	0.694
12	0.122	0.482	0.08	0.316
13	0.377	0.17	0.166	0.287

PWM

	A	C	G	T
01	0.739	-0.746	-0.609	-0.118
02	-0.632	-0.405	-1.169	0.912
03	0.491	-1.541	-1.458	0.652
04	-1.659	-2.237	-3.158	1.298
05	-4.366	-6.542	1.382	-6.542
06	0.313	0.967	-6.542	-6.542
07	1.385	-6.542	-6.542	-6.164
08	-2.02	-6.542	-6.542	1.352
09	1.385	-6.542	-6.542	-6.542
10	-0.514	-1.702	-2.664	1.147
11	-1.101	-1.541	-0.386	1.02
12	-0.716	0.656	-1.138	0.234
13	0.411	-0.385	-0.411	0.138

Standard thresholds

P-value	Threshold
0.001	2.75791
0.0005	4.278915
0.0001	7.054865