PO2F2.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO2F2.H12INVITRO.0.PSM.A
Gene (human)	POU2F2 (GeneCards)
Gene synonyms (human)	OCT2, OTF2
Gene (mouse)	Pou2f2
Gene synonyms (mouse)	Oct2, Otf2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	nYATGCAWATKnn
GC content	30.74%
Information content (bits; total / per base)	12.138 / 0.934
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	8841

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	6 (39)	0.766	0.857	0.707	0.779	0.778	0.89	3.398	3.881	199.143	384.237

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 7 experiments	median	0.985	0.98	0.859	0.861	0.685	0.721
Overall, 7 experiments	best	0.998	0.997	0.993	0.99	0.977	0.97
Methyl HT-SELEX, 2 experiments	median	0.886	0.876	0.826	0.822	0.78	0.782
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.993	0.99	0.977	0.97
Non-Methyl HT-SELEX, 5 experiments	median	0.985	0.98	0.859	0.861	0.685	0.721
Non-Methyl HT-SELEX, 5 experiments	best	0.998	0.997	0.992	0.989	0.922	0.922

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU2 {3.1.10.2} (TFClass)
TFClass ID	TFClass: 3.1.10.2.2
HGNC	HGNC:9213
MGI	MGI:101897
EntrezGene (human)	GeneID:5452 (SSTAR profile)
EntrezGene (mouse)	GeneID:18987 (SSTAR profile)
UniProt ID (human)	PO2F2_HUMAN
UniProt ID (mouse)	PO2F2_MOUSE
UniProt AC (human)	P09086 (TFClass)
UniProt AC (mouse)	Q00196 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	6 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	2

PCM	PO2F2.H12INVITRO.0.PSM.A.pcm
PWM	PO2F2.H12INVITRO.0.PSM.A.pwm
PFM	PO2F2.H12INVITRO.0.PSM.A.pfm
Alignment	PO2F2.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	PO2F2.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	PO2F2.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	PO2F2.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	PO2F2.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	PO2F2.H12INVITRO.0.PSM.A_homer_format_0.001.txt PO2F2.H12INVITRO.0.PSM.A_homer_format_0.0005.txt PO2F2.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2414.5	1224.5	2223.5	2978.5
02	717.5	1748.5	626.5	5748.5
03	7486.0	507.0	260.0	588.0
04	186.0	290.0	180.0	8185.0
05	139.0	40.0	8360.0	302.0
06	235.0	8208.0	91.0	307.0
07	6667.0	1.0	4.0	2169.0
08	5776.0	17.0	126.0	2922.0
09	8803.0	11.0	17.0	10.0
10	1242.0	351.0	234.0	7014.0
11	664.0	1028.0	1946.0	5203.0
12	3112.0	2455.0	1140.0	2134.0
13	3066.0	1566.0	2673.0	1536.0

PFM

	A	C	G	T
01	0.273	0.139	0.251	0.337
02	0.081	0.198	0.071	0.65
03	0.847	0.057	0.029	0.067
04	0.021	0.033	0.02	0.926
05	0.016	0.005	0.946	0.034
06	0.027	0.928	0.01	0.035
07	0.754	0.0	0.0	0.245
08	0.653	0.002	0.014	0.331
09	0.996	0.001	0.002	0.001
10	0.14	0.04	0.026	0.793
11	0.075	0.116	0.22	0.589
12	0.352	0.278	0.129	0.241
13	0.347	0.177	0.302	0.174

PWM

	A	C	G	T
01	0.088	-0.59	0.006	0.298
02	-1.123	-0.234	-1.258	0.955
03	1.219	-1.469	-2.133	-1.321
04	-2.464	-2.024	-2.496	1.308
05	-2.751	-3.958	1.33	-1.984
06	-2.233	1.311	-3.166	-1.968
07	1.103	-6.517	-5.866	-0.019
08	0.96	-4.743	-2.848	0.279
09	1.381	-5.116	-4.743	-5.195
10	-0.576	-1.835	-2.237	1.154
11	-1.2	-0.764	-0.127	0.856
12	0.342	0.105	-0.661	-0.035
13	0.327	-0.344	0.19	-0.363

Standard thresholds

P-value	Threshold
0.001	4.01526
0.0005	5.07116
0.0001	7.19652