Motif | PO2F2.H12CORE.2.S.B |
Gene (human) | POU2F2 (GeneCards) |
Gene synonyms (human) | OCT2, OTF2 |
Gene (mouse) | Pou2f2 |
Gene synonyms (mouse) | Oct2, Otf2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif | PO2F2.H12CORE.2.S.B |
Gene (human) | POU2F2 (GeneCards) |
Gene synonyms (human) | OCT2, OTF2 |
Gene (mouse) | Pou2f2 |
Gene synonyms (mouse) | Oct2, Otf2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif length | 13 |
Consensus | dYWTGCATATKhh |
GC content | 26.8% |
Information content (bits; total / per base) | 13.638 / 1.049 |
Data sources | HT-SELEX |
Aligned words | 6029 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 6 (39) | 0.74 | 0.867 | 0.642 | 0.802 | 0.76 | 0.903 | 3.101 | 4.837 | 183.678 | 316.244 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 7 experiments | median | 0.985 | 0.976 | 0.857 | 0.86 | 0.686 | 0.72 |
best | 0.995 | 0.993 | 0.984 | 0.978 | 0.942 | 0.923 | |
Methyl HT-SELEX, 2 experiments | median | 0.915 | 0.9 | 0.833 | 0.826 | 0.769 | 0.769 |
best | 0.987 | 0.98 | 0.974 | 0.961 | 0.942 | 0.923 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.985 | 0.976 | 0.857 | 0.86 | 0.686 | 0.72 |
best | 0.995 | 0.993 | 0.984 | 0.978 | 0.89 | 0.891 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU2 {3.1.10.2} (TFClass) |
TFClass ID | TFClass: 3.1.10.2.2 |
HGNC | HGNC:9213 |
MGI | MGI:101897 |
EntrezGene (human) | GeneID:5452 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18987 (SSTAR profile) |
UniProt ID (human) | PO2F2_HUMAN |
UniProt ID (mouse) | PO2F2_MOUSE |
UniProt AC (human) | P09086 (TFClass) |
UniProt AC (mouse) | Q00196 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 6 human, 0 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 2 |
PCM | PO2F2.H12CORE.2.S.B.pcm |
PWM | PO2F2.H12CORE.2.S.B.pwm |
PFM | PO2F2.H12CORE.2.S.B.pfm |
Alignment | PO2F2.H12CORE.2.S.B.words.tsv |
Threshold to P-value map | PO2F2.H12CORE.2.S.B.thr |
Motif in other formats | |
JASPAR format | PO2F2.H12CORE.2.S.B_jaspar_format.txt |
MEME format | PO2F2.H12CORE.2.S.B_meme_format.meme |
Transfac format | PO2F2.H12CORE.2.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 3157.5 | 713.5 | 818.5 | 1339.5 |
02 | 800.0 | 1005.0 | 467.0 | 3757.0 |
03 | 2465.0 | 321.0 | 349.0 | 2894.0 |
04 | 285.0 | 159.0 | 62.0 | 5523.0 |
05 | 17.0 | 0.0 | 6012.0 | 0.0 |
06 | 2061.0 | 3968.0 | 0.0 | 0.0 |
07 | 6028.0 | 0.0 | 0.0 | 1.0 |
08 | 198.0 | 0.0 | 0.0 | 5831.0 |
09 | 6029.0 | 0.0 | 0.0 | 0.0 |
10 | 901.0 | 273.0 | 103.0 | 4752.0 |
11 | 500.0 | 321.0 | 1024.0 | 4184.0 |
12 | 735.5 | 2906.5 | 481.5 | 1905.5 |
13 | 2274.75 | 1024.75 | 998.75 | 1730.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.524 | 0.118 | 0.136 | 0.222 |
02 | 0.133 | 0.167 | 0.077 | 0.623 |
03 | 0.409 | 0.053 | 0.058 | 0.48 |
04 | 0.047 | 0.026 | 0.01 | 0.916 |
05 | 0.003 | 0.0 | 0.997 | 0.0 |
06 | 0.342 | 0.658 | 0.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.033 | 0.0 | 0.0 | 0.967 |
09 | 1.0 | 0.0 | 0.0 | 0.0 |
10 | 0.149 | 0.045 | 0.017 | 0.788 |
11 | 0.083 | 0.053 | 0.17 | 0.694 |
12 | 0.122 | 0.482 | 0.08 | 0.316 |
13 | 0.377 | 0.17 | 0.166 | 0.287 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.739 | -0.746 | -0.609 | -0.118 |
02 | -0.632 | -0.405 | -1.169 | 0.912 |
03 | 0.491 | -1.541 | -1.458 | 0.652 |
04 | -1.659 | -2.237 | -3.158 | 1.298 |
05 | -4.366 | -6.542 | 1.382 | -6.542 |
06 | 0.313 | 0.967 | -6.542 | -6.542 |
07 | 1.385 | -6.542 | -6.542 | -6.164 |
08 | -2.02 | -6.542 | -6.542 | 1.352 |
09 | 1.385 | -6.542 | -6.542 | -6.542 |
10 | -0.514 | -1.702 | -2.664 | 1.147 |
11 | -1.101 | -1.541 | -0.386 | 1.02 |
12 | -0.716 | 0.656 | -1.138 | 0.234 |
13 | 0.411 | -0.385 | -0.411 | 0.138 |
P-value | Threshold |
---|---|
0.001 | 2.75791 |
0.0005 | 4.278915 |
0.0001 | 7.054865 |