MotifPO2F2.H12CORE.0.PSM.A
Gene (human)POU2F2
(GeneCards)
Gene synonyms (human)OCT2, OTF2
Gene (mouse)Pou2f2
Gene synonyms (mouse)Oct2, Otf2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusdYATGCAWAWd
GC content29.77%
Information content (bits; total / per base)12.458 / 1.133
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (39) 0.771 0.869 0.715 0.794 0.795 0.907 3.636 4.187 203.481 395.357

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 7 experiments median 0.981 0.976 0.857 0.859 0.685 0.72
best 0.998 0.996 0.991 0.987 0.97 0.962
Methyl HT-SELEX, 2 experiments median 0.879 0.87 0.817 0.815 0.775 0.775
best 0.997 0.995 0.991 0.987 0.97 0.962
Non-Methyl HT-SELEX, 5 experiments median 0.981 0.976 0.857 0.859 0.685 0.72
best 0.998 0.996 0.99 0.986 0.913 0.913
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU2 {3.1.10.2} (TFClass)
TFClass IDTFClass: 3.1.10.2.2
HGNCHGNC:9213
MGIMGI:101897
EntrezGene (human)GeneID:5452
(SSTAR profile)
EntrezGene (mouse)GeneID:18987
(SSTAR profile)
UniProt ID (human)PO2F2_HUMAN
UniProt ID (mouse)PO2F2_MOUSE
UniProt AC (human)P09086
(TFClass)
UniProt AC (mouse)Q00196
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 2
PCM
ACGT
01459.0142.0184.0215.0
02142.0281.040.0537.0
03979.06.05.010.0
044.03.05.0988.0
054.02.0963.031.0
0660.0852.010.078.0
07974.02.00.024.0
08676.015.071.0238.0
09971.08.07.014.0
10100.071.080.0749.0
11211.0146.0382.0261.0
PFM
ACGT
010.4590.1420.1840.215
020.1420.2810.040.537
030.9790.0060.0050.01
040.0040.0030.0050.988
050.0040.0020.9630.031
060.060.8520.010.078
070.9740.0020.00.024
080.6760.0150.0710.238
090.9710.0080.0070.014
100.10.0710.080.749
110.2110.1460.3820.261
PWM
ACGT
010.604-0.56-0.304-0.15
02-0.560.116-1.7970.761
031.36-3.484-3.622-3.066
04-3.783-3.975-3.6221.369
05-3.783-4.2131.344-2.04
06-1.4061.221-3.066-1.15
071.355-4.213-4.982-2.281
080.99-2.711-1.242-0.049
091.352-3.253-3.362-2.773
10-0.906-1.242-1.1251.093
11-0.168-0.5330.4220.043
Standard thresholds
P-value Threshold
0.001 3.834955
0.0005 4.93799
0.0001 7.250675