PO2F2.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO2F2.H12CORE.0.PSM.A
Gene (human)	POU2F2 (GeneCards)
Gene synonyms (human)	OCT2, OTF2
Gene (mouse)	Pou2f2
Gene synonyms (mouse)	Oct2, Otf2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	dYATGCAWAWd
GC content	29.77%
Information content (bits; total / per base)	12.458 / 1.133
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	6 (39)	0.771	0.869	0.715	0.794	0.795	0.907	3.636	4.187	203.481	395.357

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 7 experiments	median	0.981	0.976	0.857	0.859	0.685	0.72
Overall, 7 experiments	best	0.998	0.996	0.991	0.987	0.97	0.962
Methyl HT-SELEX, 2 experiments	median	0.879	0.87	0.817	0.815	0.775	0.775
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.991	0.987	0.97	0.962
Non-Methyl HT-SELEX, 5 experiments	median	0.981	0.976	0.857	0.859	0.685	0.72
Non-Methyl HT-SELEX, 5 experiments	best	0.998	0.996	0.99	0.986	0.913	0.913

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU2 {3.1.10.2} (TFClass)
TFClass ID	TFClass: 3.1.10.2.2
HGNC	HGNC:9213
MGI	MGI:101897
EntrezGene (human)	GeneID:5452 (SSTAR profile)
EntrezGene (mouse)	GeneID:18987 (SSTAR profile)
UniProt ID (human)	PO2F2_HUMAN
UniProt ID (mouse)	PO2F2_MOUSE
UniProt AC (human)	P09086 (TFClass)
UniProt AC (mouse)	Q00196 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	6 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	2

PCM	PO2F2.H12CORE.0.PSM.A.pcm
PWM	PO2F2.H12CORE.0.PSM.A.pwm
PFM	PO2F2.H12CORE.0.PSM.A.pfm
Alignment	PO2F2.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	PO2F2.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	PO2F2.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	PO2F2.H12CORE.0.PSM.A_meme_format.meme
Transfac format	PO2F2.H12CORE.0.PSM.A_transfac_format.txt
Homer format	PO2F2.H12CORE.0.PSM.A_homer_format_0.001.txt PO2F2.H12CORE.0.PSM.A_homer_format_0.0005.txt PO2F2.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	459.0	142.0	184.0	215.0
02	142.0	281.0	40.0	537.0
03	979.0	6.0	5.0	10.0
04	4.0	3.0	5.0	988.0
05	4.0	2.0	963.0	31.0
06	60.0	852.0	10.0	78.0
07	974.0	2.0	0.0	24.0
08	676.0	15.0	71.0	238.0
09	971.0	8.0	7.0	14.0
10	100.0	71.0	80.0	749.0
11	211.0	146.0	382.0	261.0

PFM

	A	C	G	T
01	0.459	0.142	0.184	0.215
02	0.142	0.281	0.04	0.537
03	0.979	0.006	0.005	0.01
04	0.004	0.003	0.005	0.988
05	0.004	0.002	0.963	0.031
06	0.06	0.852	0.01	0.078
07	0.974	0.002	0.0	0.024
08	0.676	0.015	0.071	0.238
09	0.971	0.008	0.007	0.014
10	0.1	0.071	0.08	0.749
11	0.211	0.146	0.382	0.261

PWM

	A	C	G	T
01	0.604	-0.56	-0.304	-0.15
02	-0.56	0.116	-1.797	0.761
03	1.36	-3.484	-3.622	-3.066
04	-3.783	-3.975	-3.622	1.369
05	-3.783	-4.213	1.344	-2.04
06	-1.406	1.221	-3.066	-1.15
07	1.355	-4.213	-4.982	-2.281
08	0.99	-2.711	-1.242	-0.049
09	1.352	-3.253	-3.362	-2.773
10	-0.906	-1.242	-1.125	1.093
11	-0.168	-0.533	0.422	0.043

Standard thresholds

P-value	Threshold
0.001	3.834955
0.0005	4.93799
0.0001	7.250675