Motif | PO2F2.H12CORE.0.PSM.A |
Gene (human) | POU2F2 (GeneCards) |
Gene synonyms (human) | OCT2, OTF2 |
Gene (mouse) | Pou2f2 |
Gene synonyms (mouse) | Oct2, Otf2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | PO2F2.H12CORE.0.PSM.A |
Gene (human) | POU2F2 (GeneCards) |
Gene synonyms (human) | OCT2, OTF2 |
Gene (mouse) | Pou2f2 |
Gene synonyms (mouse) | Oct2, Otf2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 11 |
Consensus | dYATGCAWAWd |
GC content | 29.77% |
Information content (bits; total / per base) | 12.458 / 1.133 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 1000 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 6 (39) | 0.771 | 0.869 | 0.715 | 0.794 | 0.795 | 0.907 | 3.636 | 4.187 | 203.481 | 395.357 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 7 experiments | median | 0.981 | 0.976 | 0.857 | 0.859 | 0.685 | 0.72 |
best | 0.998 | 0.996 | 0.991 | 0.987 | 0.97 | 0.962 | |
Methyl HT-SELEX, 2 experiments | median | 0.879 | 0.87 | 0.817 | 0.815 | 0.775 | 0.775 |
best | 0.997 | 0.995 | 0.991 | 0.987 | 0.97 | 0.962 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.981 | 0.976 | 0.857 | 0.859 | 0.685 | 0.72 |
best | 0.998 | 0.996 | 0.99 | 0.986 | 0.913 | 0.913 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU2 {3.1.10.2} (TFClass) |
TFClass ID | TFClass: 3.1.10.2.2 |
HGNC | HGNC:9213 |
MGI | MGI:101897 |
EntrezGene (human) | GeneID:5452 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18987 (SSTAR profile) |
UniProt ID (human) | PO2F2_HUMAN |
UniProt ID (mouse) | PO2F2_MOUSE |
UniProt AC (human) | P09086 (TFClass) |
UniProt AC (mouse) | Q00196 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 6 human, 0 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 2 |
PCM | PO2F2.H12CORE.0.PSM.A.pcm |
PWM | PO2F2.H12CORE.0.PSM.A.pwm |
PFM | PO2F2.H12CORE.0.PSM.A.pfm |
Alignment | PO2F2.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | PO2F2.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | PO2F2.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | PO2F2.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | PO2F2.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 459.0 | 142.0 | 184.0 | 215.0 |
02 | 142.0 | 281.0 | 40.0 | 537.0 |
03 | 979.0 | 6.0 | 5.0 | 10.0 |
04 | 4.0 | 3.0 | 5.0 | 988.0 |
05 | 4.0 | 2.0 | 963.0 | 31.0 |
06 | 60.0 | 852.0 | 10.0 | 78.0 |
07 | 974.0 | 2.0 | 0.0 | 24.0 |
08 | 676.0 | 15.0 | 71.0 | 238.0 |
09 | 971.0 | 8.0 | 7.0 | 14.0 |
10 | 100.0 | 71.0 | 80.0 | 749.0 |
11 | 211.0 | 146.0 | 382.0 | 261.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.459 | 0.142 | 0.184 | 0.215 |
02 | 0.142 | 0.281 | 0.04 | 0.537 |
03 | 0.979 | 0.006 | 0.005 | 0.01 |
04 | 0.004 | 0.003 | 0.005 | 0.988 |
05 | 0.004 | 0.002 | 0.963 | 0.031 |
06 | 0.06 | 0.852 | 0.01 | 0.078 |
07 | 0.974 | 0.002 | 0.0 | 0.024 |
08 | 0.676 | 0.015 | 0.071 | 0.238 |
09 | 0.971 | 0.008 | 0.007 | 0.014 |
10 | 0.1 | 0.071 | 0.08 | 0.749 |
11 | 0.211 | 0.146 | 0.382 | 0.261 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.604 | -0.56 | -0.304 | -0.15 |
02 | -0.56 | 0.116 | -1.797 | 0.761 |
03 | 1.36 | -3.484 | -3.622 | -3.066 |
04 | -3.783 | -3.975 | -3.622 | 1.369 |
05 | -3.783 | -4.213 | 1.344 | -2.04 |
06 | -1.406 | 1.221 | -3.066 | -1.15 |
07 | 1.355 | -4.213 | -4.982 | -2.281 |
08 | 0.99 | -2.711 | -1.242 | -0.049 |
09 | 1.352 | -3.253 | -3.362 | -2.773 |
10 | -0.906 | -1.242 | -1.125 | 1.093 |
11 | -0.168 | -0.533 | 0.422 | 0.043 |
P-value | Threshold |
---|---|
0.001 | 3.834955 |
0.0005 | 4.93799 |
0.0001 | 7.250675 |