PO2F1.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO2F1.H12INVIVO.0.PS.A
Gene (human)	POU2F1 (GeneCards)
Gene synonyms (human)	OCT1, OTF1
Gene (mouse)	Pou2f1
Gene synonyms (mouse)	Oct-1, Otf-1, Otf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	hYATGMAWATd
GC content	26.11%
Information content (bits; total / per base)	13.766 / 1.251
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (52)	0.716	0.95	0.603	0.907	0.657	0.95	2.268	4.546	7.139	370.444
Mouse	1 (7)	0.751	0.8	0.673	0.729	0.709	0.751	2.956	3.206	55.276	69.553

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.992	0.988	0.951	0.945	0.834	0.849
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.993	0.991	0.945	0.943

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU2 {3.1.10.2} (TFClass)
TFClass ID	TFClass: 3.1.10.2.1
HGNC	HGNC:9212
MGI	MGI:101898
EntrezGene (human)	GeneID:5451 (SSTAR profile)
EntrezGene (mouse)	GeneID:18986 (SSTAR profile)
UniProt ID (human)	PO2F1_HUMAN
UniProt ID (mouse)	PO2F1_MOUSE
UniProt AC (human)	P14859 (TFClass)
UniProt AC (mouse)	P25425 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	PO2F1.H12INVIVO.0.PS.A.pcm
PWM	PO2F1.H12INVIVO.0.PS.A.pwm
PFM	PO2F1.H12INVIVO.0.PS.A.pfm
Alignment	PO2F1.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	PO2F1.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	PO2F1.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	PO2F1.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	PO2F1.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	PO2F1.H12INVIVO.0.PS.A_homer_format_0.001.txt PO2F1.H12INVIVO.0.PS.A_homer_format_0.0005.txt PO2F1.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	430.0	190.0	97.0	283.0
02	99.0	195.0	8.0	698.0
03	981.0	10.0	6.0	3.0
04	4.0	2.0	1.0	993.0
05	4.0	1.0	990.0	5.0
06	151.0	733.0	10.0	106.0
07	954.0	9.0	0.0	37.0
08	618.0	3.0	54.0	325.0
09	996.0	0.0	0.0	4.0
10	23.0	24.0	15.0	938.0
11	184.0	68.0	456.0	292.0

PFM

	A	C	G	T
01	0.43	0.19	0.097	0.283
02	0.099	0.195	0.008	0.698
03	0.981	0.01	0.006	0.003
04	0.004	0.002	0.001	0.993
05	0.004	0.001	0.99	0.005
06	0.151	0.733	0.01	0.106
07	0.954	0.009	0.0	0.037
08	0.618	0.003	0.054	0.325
09	0.996	0.0	0.0	0.004
10	0.023	0.024	0.015	0.938
11	0.184	0.068	0.456	0.292

PWM

	A	C	G	T
01	0.539	-0.272	-0.936	0.123
02	-0.916	-0.247	-3.253	1.022
03	1.362	-3.066	-3.484	-3.975
04	-3.783	-4.213	-4.525	1.374
05	-3.783	-4.525	1.371	-3.622
06	-0.5	1.071	-3.066	-0.849
07	1.334	-3.156	-4.982	-1.872
08	0.901	-3.975	-1.508	0.261
09	1.377	-4.982	-4.982	-3.783
10	-2.32	-2.281	-2.711	1.317
11	-0.304	-1.284	0.598	0.154

Standard thresholds

P-value	Threshold
0.001	3.07346
0.0005	4.347265
0.0001	6.801385