PO2F1.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO2F1.H12INVITRO.0.PS.A
Gene (human)	POU2F1 (GeneCards)
Gene synonyms (human)	OCT1, OTF1
Gene (mouse)	Pou2f1
Gene synonyms (mouse)	Oct-1, Otf-1, Otf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	dYATGCAAATbnv
GC content	29.78%
Information content (bits; total / per base)	14.433 / 1.11
Data sources	ChIP-Seq + HT-SELEX
Aligned words	5757

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (52)	0.697	0.939	0.59	0.906	0.62	0.92	2.149	4.161	7.143	340.959
Mouse	1 (7)	0.751	0.794	0.683	0.723	0.684	0.716	2.862	3.061	53.409	60.0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.994	0.991	0.955	0.951	0.839	0.854
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.996	0.994	0.947	0.946

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU2 {3.1.10.2} (TFClass)
TFClass ID	TFClass: 3.1.10.2.1
HGNC	HGNC:9212
MGI	MGI:101898
EntrezGene (human)	GeneID:5451 (SSTAR profile)
EntrezGene (mouse)	GeneID:18986 (SSTAR profile)
UniProt ID (human)	PO2F1_HUMAN
UniProt ID (mouse)	PO2F1_MOUSE
UniProt AC (human)	P14859 (TFClass)
UniProt AC (mouse)	P25425 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	PO2F1.H12INVITRO.0.PS.A.pcm
PWM	PO2F1.H12INVITRO.0.PS.A.pwm
PFM	PO2F1.H12INVITRO.0.PS.A.pfm
Alignment	PO2F1.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	PO2F1.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	PO2F1.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	PO2F1.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	PO2F1.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	PO2F1.H12INVITRO.0.PS.A_homer_format_0.001.txt PO2F1.H12INVITRO.0.PS.A_homer_format_0.0005.txt PO2F1.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1670.25	759.25	1171.25	2156.25
02	221.5	933.5	138.5	4463.5
03	5527.0	119.0	44.0	67.0
04	15.0	86.0	35.0	5621.0
05	4.0	0.0	5650.0	103.0
06	110.0	5462.0	35.0	150.0
07	4147.0	0.0	3.0	1607.0
08	4720.0	3.0	51.0	983.0
09	5753.0	4.0	0.0	0.0
10	295.0	104.0	127.0	5231.0
11	459.0	671.0	1463.0	3164.0
12	2051.0	1526.0	868.0	1312.0
13	1843.0	1010.0	2027.0	877.0

PFM

	A	C	G	T
01	0.29	0.132	0.203	0.375
02	0.038	0.162	0.024	0.775
03	0.96	0.021	0.008	0.012
04	0.003	0.015	0.006	0.976
05	0.001	0.0	0.981	0.018
06	0.019	0.949	0.006	0.026
07	0.72	0.0	0.001	0.279
08	0.82	0.001	0.009	0.171
09	0.999	0.001	0.0	0.0
10	0.051	0.018	0.022	0.909
11	0.08	0.117	0.254	0.55
12	0.356	0.265	0.151	0.228
13	0.32	0.175	0.352	0.152

PWM

	A	C	G	T
01	0.149	-0.638	-0.206	0.404
02	-1.863	-0.432	-2.327	1.131
03	1.344	-2.476	-3.441	-3.037
04	-4.431	-2.794	-3.658	1.361
05	-5.455	-6.501	1.366	-2.618
06	-2.553	1.333	-3.658	-2.248
07	1.057	-6.501	-5.632	0.11
08	1.187	-5.632	-3.3	-0.381
09	1.384	-5.455	-6.501	-6.501
10	-1.579	-2.608	-2.412	1.289
11	-1.14	-0.761	0.016	0.787
12	0.354	0.058	-0.505	-0.092
13	0.247	-0.354	0.342	-0.494

Standard thresholds

P-value	Threshold
0.001	2.54076
0.0005	3.86911
0.0001	6.64032