MotifPKNX2.H12INVITRO.1.SM.B
Gene (human)PKNOX2
(GeneCards)
Gene synonyms (human)PREP2
Gene (mouse)Pknox2
Gene synonyms (mouse)Prep2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusnTGACAGvYdn
GC content52.34%
Information content (bits; total / per base)11.55 / 1.05
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9614

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.994 0.99 0.984 0.977 0.969 0.955
best 0.996 0.994 0.99 0.984 0.98 0.971
Methyl HT-SELEX, 2 experiments median 0.988 0.982 0.978 0.966 0.948 0.932
best 0.991 0.988 0.979 0.969 0.962 0.943
Non-Methyl HT-SELEX, 2 experiments median 0.996 0.993 0.989 0.984 0.978 0.968
best 0.996 0.994 0.99 0.984 0.98 0.971
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyPKNOX {3.1.4.5} (TFClass)
TFClass IDTFClass: 3.1.4.5.2
HGNCHGNC:16714
MGIMGI:2445415
EntrezGene (human)GeneID:63876
(SSTAR profile)
EntrezGene (mouse)GeneID:208076
(SSTAR profile)
UniProt ID (human)PKNX2_HUMAN
UniProt ID (mouse)PKNX2_MOUSE
UniProt AC (human)Q96KN3
(TFClass)
UniProt AC (mouse)Q8BG99
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
012125.752411.752138.752937.75
02243.0359.043.08969.0
030.00.09614.00.0
049598.00.016.00.0
050.09614.00.00.0
069328.00.0286.00.0
07282.0629.07848.0855.0
081280.03790.04013.0531.0
09461.02694.0963.05496.0
101578.01141.05236.01659.0
111853.51818.52734.53207.5
PFM
ACGT
010.2210.2510.2220.306
020.0250.0370.0040.933
030.00.01.00.0
040.9980.00.0020.0
050.01.00.00.0
060.970.00.030.0
070.0290.0650.8160.089
080.1330.3940.4170.055
090.0480.280.10.572
100.1640.1190.5450.173
110.1930.1890.2840.334
PWM
ACGT
01-0.1230.003-0.1170.201
02-2.283-1.896-3.9721.316
03-6.956-6.9561.386-6.956
041.384-6.956-4.879-6.956
05-6.9561.386-6.956-6.956
061.355-6.956-2.122-6.956
07-2.136-1.3381.183-1.032
08-0.6290.4550.512-1.507
09-1.6470.114-0.9130.827
10-0.42-0.7440.778-0.37
11-0.26-0.2790.1290.288
Standard thresholds
P-value Threshold
0.001 4.091945
0.0005 5.361025
0.0001 7.578415