MotifPKNX1.H12INVITRO.0.P.B
Gene (human)PKNOX1
(GeneCards)
Gene synonyms (human)PREP1
Gene (mouse)Pknox1
Gene synonyms (mouse)Prep1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusbbYSATTGGYhv
GC content49.75%
Information content (bits; total / per base)11.375 / 0.948
Data sourcesChIP-Seq
Aligned words995

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (35) 0.927 0.939 0.831 0.858 0.895 0.914 3.437 3.614 194.602 232.602
Mouse 5 (35) 0.913 0.935 0.82 0.853 0.898 0.92 3.572 3.76 204.796 244.06

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.551 0.533 0.532 0.522 0.52 0.516
best 0.681 0.625 0.638 0.596 0.601 0.573
Methyl HT-SELEX, 2 experiments median 0.531 0.522 0.519 0.515 0.513 0.51
best 0.579 0.551 0.556 0.537 0.539 0.527
Non-Methyl HT-SELEX, 4 experiments median 0.579 0.549 0.556 0.537 0.539 0.528
best 0.681 0.625 0.638 0.596 0.601 0.573

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.672 15.176 0.193 0.138
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyPKNOX {3.1.4.5} (TFClass)
TFClass IDTFClass: 3.1.4.5.1
HGNCHGNC:9022
MGIMGI:1201409
EntrezGene (human)GeneID:5316
(SSTAR profile)
EntrezGene (mouse)GeneID:18771
(SSTAR profile)
UniProt ID (human)PKNX1_HUMAN
UniProt ID (mouse)PKNX1_MOUSE
UniProt AC (human)P55347
(TFClass)
UniProt AC (mouse)O70477
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 5 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
0174.0221.0241.0459.0
0283.0457.0210.0245.0
0322.0189.040.0744.0
0432.0195.0693.075.0
05982.04.07.02.0
066.075.097.0817.0
0714.03.016.0962.0
085.01.0989.00.0
09227.06.0760.02.0
1068.0766.024.0137.0
11293.0198.092.0412.0
12260.0126.0530.079.0
PFM
ACGT
010.0740.2220.2420.461
020.0830.4590.2110.246
030.0220.190.040.748
040.0320.1960.6960.075
050.9870.0040.0070.002
060.0060.0750.0970.821
070.0140.0030.0160.967
080.0050.0010.9940.0
090.2280.0060.7640.002
100.0680.770.0240.138
110.2940.1990.0920.414
120.2610.1270.5330.079
PWM
ACGT
01-1.196-0.117-0.0310.609
02-1.0840.605-0.168-0.015
03-2.357-0.273-1.7921.091
04-2.005-0.2421.02-1.183
051.368-3.778-3.357-4.208
06-3.479-1.183-0.9311.184
07-2.768-3.97-2.6481.347
08-3.617-4.5211.375-4.978
09-0.091-3.4791.112-4.208
10-1.2791.12-2.276-0.591
110.163-0.226-0.9830.502
120.044-0.6730.753-1.132
Standard thresholds
P-value Threshold
0.001 4.37756
0.0005 5.37801
0.0001 7.352145