MotifPITX3.H12CORE.0.SM.B
Gene (human)PITX3
(GeneCards)
Gene synonyms (human)PTX3
Gene (mouse)Pitx3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusnGGATTAvn
GC content40.05%
Information content (bits; total / per base)10.877 / 1.209
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9481

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.979 0.964 0.971 0.953 0.926 0.908
best 0.992 0.988 0.988 0.981 0.966 0.946
Methyl HT-SELEX, 2 experiments median 0.971 0.952 0.965 0.942 0.944 0.918
best 0.979 0.962 0.976 0.957 0.966 0.945
Non-Methyl HT-SELEX, 4 experiments median 0.981 0.968 0.971 0.955 0.899 0.888
best 0.992 0.988 0.988 0.981 0.966 0.946

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.617 0.292 0.627 0.423
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyPITX {3.1.3.19} (TFClass)
TFClass IDTFClass: 3.1.3.19.3
HGNCHGNC:9006
MGIMGI:1100498
EntrezGene (human)GeneID:5309
(SSTAR profile)
EntrezGene (mouse)GeneID:18742
(SSTAR profile)
UniProt ID (human)PITX3_HUMAN
UniProt ID (mouse)PITX3_MOUSE
UniProt AC (human)O75364
(TFClass)
UniProt AC (mouse)O35160
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012094.252353.252608.252425.25
02652.057.08414.0358.0
031.026.09454.00.0
048237.01244.00.00.0
050.00.00.09481.0
060.0272.00.09209.0
079395.03.07.076.0
084942.01189.02441.0909.0
091509.52851.53251.51868.5
PFM
ACGT
010.2210.2480.2750.256
020.0690.0060.8870.038
030.00.0030.9970.0
040.8690.1310.00.0
050.00.00.01.0
060.00.0290.00.971
070.9910.00.0010.008
080.5210.1250.2570.096
090.1590.3010.3430.197
PWM
ACGT
01-0.124-0.0070.0960.023
02-1.288-3.6891.266-1.885
03-6.581-4.4291.383-6.943
041.245-0.644-6.943-6.943
05-6.943-6.943-6.9431.386
06-6.943-2.158-6.9431.356
071.376-6.106-5.543-3.411
080.734-0.6890.029-0.957
09-0.4510.1850.316-0.238
Standard thresholds
P-value Threshold
0.001 4.25473
0.0005 5.631135
0.0001 7.77096