MotifPIT1.H12CORE.0.SM.B
Gene (human)POU1F1
(GeneCards)
Gene synonyms (human)GHF1, PIT1
Gene (mouse)Pou1f1
Gene synonyms (mouse)Pit-1, Pit1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusnhTAATGAGATGCR
GC content36.13%
Information content (bits; total / per base)19.235 / 1.374
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words5039

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.998 0.998 0.971 0.966 0.897 0.887
best 1.0 1.0 0.997 0.997 0.957 0.954
Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.997 0.997 0.957 0.954
best 1.0 1.0 0.997 0.997 0.957 0.954
Non-Methyl HT-SELEX, 2 experiments median 0.924 0.903 0.869 0.847 0.791 0.775
best 0.998 0.998 0.971 0.966 0.897 0.887
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU1 {3.1.10.1} (TFClass)
TFClass IDTFClass: 3.1.10.1.1
HGNCHGNC:9210
MGIMGI:97588
EntrezGene (human)GeneID:5449
(SSTAR profile)
EntrezGene (mouse)GeneID:18736
(SSTAR profile)
UniProt ID (human)PIT1_HUMAN
UniProt ID (mouse)PIT1_MOUSE
UniProt AC (human)P28069
(TFClass)
UniProt AC (mouse)Q00286
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
011491.751100.751749.75696.75
02797.75815.75674.752750.75
0375.026.09.04929.0
045026.07.05.01.0
055039.00.00.00.0
060.04.04.05031.0
074.03.04052.0980.0
085025.01.04.09.0
0959.096.04300.0584.0
104809.051.0111.068.0
1176.073.043.04847.0
12122.076.04279.0562.0
13131.254686.25106.25115.25
141461.0353.02855.0370.0
PFM
ACGT
010.2960.2180.3470.138
020.1580.1620.1340.546
030.0150.0050.0020.978
040.9970.0010.0010.0
051.00.00.00.0
060.00.0010.0010.998
070.0010.0010.8040.194
080.9970.00.0010.002
090.0120.0190.8530.116
100.9540.010.0220.013
110.0150.0140.0090.962
120.0240.0150.8490.112
130.0260.930.0210.023
140.290.070.5670.073
PWM
ACGT
010.169-0.1350.328-0.591
02-0.456-0.434-0.6230.78
03-2.795-3.803-4.7311.363
041.382-4.929-5.176-5.999
051.385-6.384-6.384-6.384
06-6.384-5.327-5.3271.383
07-5.327-5.5051.167-0.251
081.382-5.999-5.327-4.731
09-3.027-2.5541.227-0.767
101.338-3.168-2.412-2.89
11-2.782-2.821-3.3311.346
12-2.319-2.7821.222-0.805
13-2.2471.312-2.455-2.375
140.148-1.2680.817-1.221
Standard thresholds
P-value Threshold
0.001 -1.29594
0.0005 0.44311
0.0001 4.078715