Motif | PIT1.H12CORE.0.SM.B |
Gene (human) | POU1F1 (GeneCards) |
Gene synonyms (human) | GHF1, PIT1 |
Gene (mouse) | Pou1f1 |
Gene synonyms (mouse) | Pit-1, Pit1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | PIT1.H12CORE.0.SM.B |
Gene (human) | POU1F1 (GeneCards) |
Gene synonyms (human) | GHF1, PIT1 |
Gene (mouse) | Pou1f1 |
Gene synonyms (mouse) | Pit-1, Pit1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 14 |
Consensus | nhTAATGAGATGCR |
GC content | 36.13% |
Information content (bits; total / per base) | 19.235 / 1.374 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 5039 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 3 experiments | median | 0.998 | 0.998 | 0.971 | 0.966 | 0.897 | 0.887 |
best | 1.0 | 1.0 | 0.997 | 0.997 | 0.957 | 0.954 | |
Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 0.997 | 0.997 | 0.957 | 0.954 |
best | 1.0 | 1.0 | 0.997 | 0.997 | 0.957 | 0.954 | |
Non-Methyl HT-SELEX, 2 experiments | median | 0.924 | 0.903 | 0.869 | 0.847 | 0.791 | 0.775 |
best | 0.998 | 0.998 | 0.971 | 0.966 | 0.897 | 0.887 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU1 {3.1.10.1} (TFClass) |
TFClass ID | TFClass: 3.1.10.1.1 |
HGNC | HGNC:9210 |
MGI | MGI:97588 |
EntrezGene (human) | GeneID:5449 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18736 (SSTAR profile) |
UniProt ID (human) | PIT1_HUMAN |
UniProt ID (mouse) | PIT1_MOUSE |
UniProt AC (human) | P28069 (TFClass) |
UniProt AC (mouse) | Q00286 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 2 |
Methyl-HT-SELEX | 1 |
PCM | PIT1.H12CORE.0.SM.B.pcm |
PWM | PIT1.H12CORE.0.SM.B.pwm |
PFM | PIT1.H12CORE.0.SM.B.pfm |
Alignment | PIT1.H12CORE.0.SM.B.words.tsv |
Threshold to P-value map | PIT1.H12CORE.0.SM.B.thr |
Motif in other formats | |
JASPAR format | PIT1.H12CORE.0.SM.B_jaspar_format.txt |
MEME format | PIT1.H12CORE.0.SM.B_meme_format.meme |
Transfac format | PIT1.H12CORE.0.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1491.75 | 1100.75 | 1749.75 | 696.75 |
02 | 797.75 | 815.75 | 674.75 | 2750.75 |
03 | 75.0 | 26.0 | 9.0 | 4929.0 |
04 | 5026.0 | 7.0 | 5.0 | 1.0 |
05 | 5039.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 4.0 | 4.0 | 5031.0 |
07 | 4.0 | 3.0 | 4052.0 | 980.0 |
08 | 5025.0 | 1.0 | 4.0 | 9.0 |
09 | 59.0 | 96.0 | 4300.0 | 584.0 |
10 | 4809.0 | 51.0 | 111.0 | 68.0 |
11 | 76.0 | 73.0 | 43.0 | 4847.0 |
12 | 122.0 | 76.0 | 4279.0 | 562.0 |
13 | 131.25 | 4686.25 | 106.25 | 115.25 |
14 | 1461.0 | 353.0 | 2855.0 | 370.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.296 | 0.218 | 0.347 | 0.138 |
02 | 0.158 | 0.162 | 0.134 | 0.546 |
03 | 0.015 | 0.005 | 0.002 | 0.978 |
04 | 0.997 | 0.001 | 0.001 | 0.0 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 0.001 | 0.001 | 0.998 |
07 | 0.001 | 0.001 | 0.804 | 0.194 |
08 | 0.997 | 0.0 | 0.001 | 0.002 |
09 | 0.012 | 0.019 | 0.853 | 0.116 |
10 | 0.954 | 0.01 | 0.022 | 0.013 |
11 | 0.015 | 0.014 | 0.009 | 0.962 |
12 | 0.024 | 0.015 | 0.849 | 0.112 |
13 | 0.026 | 0.93 | 0.021 | 0.023 |
14 | 0.29 | 0.07 | 0.567 | 0.073 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.169 | -0.135 | 0.328 | -0.591 |
02 | -0.456 | -0.434 | -0.623 | 0.78 |
03 | -2.795 | -3.803 | -4.731 | 1.363 |
04 | 1.382 | -4.929 | -5.176 | -5.999 |
05 | 1.385 | -6.384 | -6.384 | -6.384 |
06 | -6.384 | -5.327 | -5.327 | 1.383 |
07 | -5.327 | -5.505 | 1.167 | -0.251 |
08 | 1.382 | -5.999 | -5.327 | -4.731 |
09 | -3.027 | -2.554 | 1.227 | -0.767 |
10 | 1.338 | -3.168 | -2.412 | -2.89 |
11 | -2.782 | -2.821 | -3.331 | 1.346 |
12 | -2.319 | -2.782 | 1.222 | -0.805 |
13 | -2.247 | 1.312 | -2.455 | -2.375 |
14 | 0.148 | -1.268 | 0.817 | -1.221 |
P-value | Threshold |
---|---|
0.001 | -1.29594 |
0.0005 | 0.44311 |
0.0001 | 4.078715 |