Motif | PHX2B.H12CORE.0.PSM.A |
Gene (human) | PHOX2B (GeneCards) |
Gene synonyms (human) | PMX2B |
Gene (mouse) | Phox2b |
Gene synonyms (mouse) | Pmx2b |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | PHX2B.H12CORE.0.PSM.A |
Gene (human) | PHOX2B (GeneCards) |
Gene synonyms (human) | PMX2B |
Gene (mouse) | Phox2b |
Gene synonyms (mouse) | Pmx2b |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 14 |
Consensus | nnTAATTARATTAn |
GC content | 18.36% |
Information content (bits; total / per base) | 18.86 / 1.347 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 8849 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 3 (21) | 0.934 | 0.974 | 0.871 | 0.949 | 0.842 | 0.937 | 2.952 | 4.538 | 240.377 | 386.276 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.99 | 0.982 | 0.977 | 0.971 | 0.859 | 0.843 |
best | 1.0 | 1.0 | 1.0 | 0.999 | 0.995 | 0.995 | |
Methyl HT-SELEX, 2 experiments | median | 0.956 | 0.929 | 0.932 | 0.904 | 0.794 | 0.795 |
best | 1.0 | 0.999 | 0.979 | 0.978 | 0.834 | 0.806 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.99 | 0.982 | 0.981 | 0.971 | 0.927 | 0.92 |
best | 1.0 | 1.0 | 1.0 | 0.999 | 0.995 | 0.995 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | PHOX {3.1.3.18} (TFClass) |
TFClass ID | TFClass: 3.1.3.18.2 |
HGNC | HGNC:9143 |
MGI | MGI:1100882 |
EntrezGene (human) | GeneID:8929 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18935 (SSTAR profile) |
UniProt ID (human) | PHX2B_HUMAN |
UniProt ID (mouse) | PHX2B_MOUSE |
UniProt AC (human) | Q99453 (TFClass) |
UniProt AC (mouse) | O35690 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 3 human, 0 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | PHX2B.H12CORE.0.PSM.A.pcm |
PWM | PHX2B.H12CORE.0.PSM.A.pwm |
PFM | PHX2B.H12CORE.0.PSM.A.pfm |
Alignment | PHX2B.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | PHX2B.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | PHX2B.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | PHX2B.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | PHX2B.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1818.75 | 2334.75 | 3107.75 | 1587.75 |
02 | 1683.25 | 3092.25 | 1713.25 | 2360.25 |
03 | 168.0 | 81.0 | 15.0 | 8585.0 |
04 | 8749.0 | 5.0 | 86.0 | 9.0 |
05 | 8847.0 | 2.0 | 0.0 | 0.0 |
06 | 0.0 | 3.0 | 0.0 | 8846.0 |
07 | 2.0 | 27.0 | 14.0 | 8806.0 |
08 | 7372.0 | 132.0 | 1181.0 | 164.0 |
09 | 3590.0 | 234.0 | 5020.0 | 5.0 |
10 | 8394.0 | 47.0 | 351.0 | 57.0 |
11 | 3.0 | 6.0 | 19.0 | 8821.0 |
12 | 67.0 | 185.0 | 43.0 | 8554.0 |
13 | 8443.0 | 49.0 | 107.0 | 250.0 |
14 | 2315.0 | 1749.0 | 3136.0 | 1649.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.206 | 0.264 | 0.351 | 0.179 |
02 | 0.19 | 0.349 | 0.194 | 0.267 |
03 | 0.019 | 0.009 | 0.002 | 0.97 |
04 | 0.989 | 0.001 | 0.01 | 0.001 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 0.0 | 0.0 | 1.0 |
07 | 0.0 | 0.003 | 0.002 | 0.995 |
08 | 0.833 | 0.015 | 0.133 | 0.019 |
09 | 0.406 | 0.026 | 0.567 | 0.001 |
10 | 0.949 | 0.005 | 0.04 | 0.006 |
11 | 0.0 | 0.001 | 0.002 | 0.997 |
12 | 0.008 | 0.021 | 0.005 | 0.967 |
13 | 0.954 | 0.006 | 0.012 | 0.028 |
14 | 0.262 | 0.198 | 0.354 | 0.186 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.196 | 0.054 | 0.34 | -0.331 |
02 | -0.273 | 0.335 | -0.255 | 0.065 |
03 | -2.565 | -3.281 | -4.854 | 1.355 |
04 | 1.374 | -5.719 | -3.222 | -5.28 |
05 | 1.385 | -6.251 | -6.882 | -6.882 |
06 | -6.882 | -6.04 | -6.882 | 1.385 |
07 | -6.251 | -4.326 | -4.913 | 1.381 |
08 | 1.203 | -2.803 | -0.627 | -2.589 |
09 | 0.484 | -2.238 | 0.819 | -5.719 |
10 | 1.333 | -3.805 | -1.836 | -3.621 |
11 | -6.04 | -5.59 | -4.645 | 1.382 |
12 | -3.465 | -2.47 | -3.89 | 1.352 |
13 | 1.339 | -3.766 | -3.009 | -2.172 |
14 | 0.045 | -0.235 | 0.349 | -0.293 |
P-value | Threshold |
---|---|
0.001 | -1.90169 |
0.0005 | -0.08094 |
0.0001 | 3.74221 |