MotifPHX2A.H12CORE.1.SM.B
Gene (human)PHOX2A
(GeneCards)
Gene synonyms (human)ARIX, PMX2A
Gene (mouse)Phox2a
Gene synonyms (mouse)Arix, Phox2, Pmx2, Pmx2a
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusvnbYAATTAvbn
GC content34.51%
Information content (bits; total / per base)11.005 / 0.917
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7535

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (4) 0.833 0.866 0.686 0.718 0.76 0.795 2.174 2.338 52.184 87.495

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.964 0.942 0.945 0.916 0.914 0.878
best 0.98 0.968 0.966 0.947 0.924 0.903
Methyl HT-SELEX, 1 experiments median 0.96 0.934 0.944 0.912 0.914 0.878
best 0.96 0.934 0.944 0.912 0.914 0.878
Non-Methyl HT-SELEX, 3 experiments median 0.967 0.947 0.946 0.918 0.914 0.878
best 0.98 0.968 0.966 0.947 0.924 0.903
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyPHOX {3.1.3.18} (TFClass)
TFClass IDTFClass: 3.1.3.18.1
HGNCHGNC:691
MGIMGI:106633
EntrezGene (human)GeneID:401
(SSTAR profile)
EntrezGene (mouse)GeneID:11859
(SSTAR profile)
UniProt ID (human)PHX2A_HUMAN
UniProt ID (mouse)PHX2A_MOUSE
UniProt AC (human)O14813
(TFClass)
UniProt AC (mouse)Q62066
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
013028.251583.251655.251268.25
021587.52582.51375.51989.5
03830.02860.02525.01320.0
04349.02891.0301.03994.0
056708.061.0764.02.0
067535.00.00.00.0
070.00.00.07535.0
080.00.00.07535.0
097535.00.00.00.0
102463.01445.03431.0196.0
11469.753722.751767.751574.75
121286.251913.252326.252009.25
PFM
ACGT
010.4020.210.220.168
020.2110.3430.1830.264
030.110.380.3350.175
040.0460.3840.040.53
050.890.0080.1010.0
061.00.00.00.0
070.00.00.01.0
080.00.00.01.0
091.00.00.00.0
100.3270.1920.4550.026
110.0620.4940.2350.209
120.1710.2540.3090.267
PWM
ACGT
010.474-0.174-0.129-0.395
02-0.1710.315-0.3140.055
03-0.8180.4170.293-0.355
04-1.6810.428-1.8280.751
051.269-3.395-0.901-6.1
061.385-6.739-6.739-6.739
07-6.739-6.739-6.7391.385
08-6.739-6.739-6.7391.385
091.385-6.739-6.739-6.739
100.268-0.2650.599-2.253
11-1.3850.681-0.063-0.179
12-0.3810.0160.2110.064
Standard thresholds
P-value Threshold
0.001 4.314085
0.0005 5.76941
0.0001 7.84189