Motif | PHX2A.H12CORE.0.PS.A |
Gene (human) | PHOX2A (GeneCards) |
Gene synonyms (human) | ARIX, PMX2A |
Gene (mouse) | Phox2a |
Gene synonyms (mouse) | Arix, Phox2, Pmx2, Pmx2a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | PHX2A.H12CORE.0.PS.A |
Gene (human) | PHOX2A (GeneCards) |
Gene synonyms (human) | ARIX, PMX2A |
Gene (mouse) | Phox2a |
Gene synonyms (mouse) | Arix, Phox2, Pmx2, Pmx2a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 20 |
Consensus | vnnnnnbTAAYYhRATTAvn |
GC content | 34.68% |
Information content (bits; total / per base) | 13.725 / 0.686 |
Data sources | ChIP-Seq + HT-SELEX |
Aligned words | 7335 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 1 (4) | 0.888 | 0.931 | 0.818 | 0.871 | 0.839 | 0.901 | 3.084 | 3.503 | 94.562 | 164.796 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.98 | 0.965 | 0.963 | 0.944 | 0.921 | 0.893 |
best | 0.995 | 0.992 | 0.989 | 0.983 | 0.923 | 0.92 | |
Methyl HT-SELEX, 1 experiments | median | 0.973 | 0.952 | 0.958 | 0.933 | 0.922 | 0.894 |
best | 0.973 | 0.952 | 0.958 | 0.933 | 0.922 | 0.894 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.986 | 0.977 | 0.967 | 0.953 | 0.92 | 0.892 |
best | 0.995 | 0.992 | 0.989 | 0.983 | 0.923 | 0.92 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | PHOX {3.1.3.18} (TFClass) |
TFClass ID | TFClass: 3.1.3.18.1 |
HGNC | HGNC:691 |
MGI | MGI:106633 |
EntrezGene (human) | GeneID:401 (SSTAR profile) |
EntrezGene (mouse) | GeneID:11859 (SSTAR profile) |
UniProt ID (human) | PHX2A_HUMAN |
UniProt ID (mouse) | PHX2A_MOUSE |
UniProt AC (human) | O14813 (TFClass) |
UniProt AC (mouse) | Q62066 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 1 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | PHX2A.H12CORE.0.PS.A.pcm |
PWM | PHX2A.H12CORE.0.PS.A.pwm |
PFM | PHX2A.H12CORE.0.PS.A.pfm |
Alignment | PHX2A.H12CORE.0.PS.A.words.tsv |
Threshold to P-value map | PHX2A.H12CORE.0.PS.A.thr |
Motif in other formats | |
JASPAR format | PHX2A.H12CORE.0.PS.A_jaspar_format.txt |
MEME format | PHX2A.H12CORE.0.PS.A_meme_format.meme |
Transfac format | PHX2A.H12CORE.0.PS.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1456.5 | 3011.5 | 1476.5 | 1390.5 |
02 | 1664.0 | 2517.0 | 1684.0 | 1470.0 |
03 | 1543.0 | 2686.0 | 1619.0 | 1487.0 |
04 | 1630.0 | 2005.0 | 1951.0 | 1749.0 |
05 | 1879.0 | 2158.0 | 1862.0 | 1436.0 |
06 | 2084.0 | 1826.0 | 2202.0 | 1223.0 |
07 | 886.0 | 2750.0 | 1810.0 | 1889.0 |
08 | 397.0 | 474.0 | 223.0 | 6241.0 |
09 | 6270.0 | 151.0 | 649.0 | 265.0 |
10 | 7072.0 | 116.0 | 111.0 | 36.0 |
11 | 337.0 | 926.0 | 256.0 | 5816.0 |
12 | 10.0 | 2794.0 | 493.0 | 4038.0 |
13 | 2159.0 | 843.0 | 605.0 | 3728.0 |
14 | 5216.0 | 266.0 | 1846.0 | 7.0 |
15 | 6705.0 | 62.0 | 456.0 | 112.0 |
16 | 0.0 | 8.0 | 0.0 | 7327.0 |
17 | 85.0 | 499.0 | 46.0 | 6705.0 |
18 | 5961.0 | 117.0 | 937.0 | 320.0 |
19 | 1654.0 | 1512.0 | 3354.0 | 815.0 |
20 | 1192.75 | 1756.75 | 2820.75 | 1564.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.199 | 0.411 | 0.201 | 0.19 |
02 | 0.227 | 0.343 | 0.23 | 0.2 |
03 | 0.21 | 0.366 | 0.221 | 0.203 |
04 | 0.222 | 0.273 | 0.266 | 0.238 |
05 | 0.256 | 0.294 | 0.254 | 0.196 |
06 | 0.284 | 0.249 | 0.3 | 0.167 |
07 | 0.121 | 0.375 | 0.247 | 0.258 |
08 | 0.054 | 0.065 | 0.03 | 0.851 |
09 | 0.855 | 0.021 | 0.088 | 0.036 |
10 | 0.964 | 0.016 | 0.015 | 0.005 |
11 | 0.046 | 0.126 | 0.035 | 0.793 |
12 | 0.001 | 0.381 | 0.067 | 0.551 |
13 | 0.294 | 0.115 | 0.082 | 0.508 |
14 | 0.711 | 0.036 | 0.252 | 0.001 |
15 | 0.914 | 0.008 | 0.062 | 0.015 |
16 | 0.0 | 0.001 | 0.0 | 0.999 |
17 | 0.012 | 0.068 | 0.006 | 0.914 |
18 | 0.813 | 0.016 | 0.128 | 0.044 |
19 | 0.225 | 0.206 | 0.457 | 0.111 |
20 | 0.163 | 0.24 | 0.385 | 0.213 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.23 | 0.496 | -0.216 | -0.276 |
02 | -0.097 | 0.316 | -0.085 | -0.221 |
03 | -0.172 | 0.381 | -0.124 | -0.209 |
04 | -0.118 | 0.089 | 0.062 | -0.047 |
05 | 0.024 | 0.163 | 0.015 | -0.244 |
06 | 0.128 | -0.004 | 0.183 | -0.404 |
07 | -0.726 | 0.405 | -0.013 | 0.03 |
08 | -1.526 | -1.349 | -2.098 | 1.224 |
09 | 1.229 | -2.483 | -1.036 | -1.927 |
10 | 1.349 | -2.743 | -2.786 | -3.872 |
11 | -1.689 | -0.682 | -1.961 | 1.153 |
12 | -5.012 | 0.421 | -1.31 | 0.789 |
13 | 0.163 | -0.776 | -1.106 | 0.709 |
14 | 1.045 | -1.924 | 0.007 | -5.293 |
15 | 1.296 | -3.353 | -1.388 | -2.777 |
16 | -6.716 | -5.19 | -6.716 | 1.384 |
17 | -3.047 | -1.298 | -3.639 | 1.296 |
18 | 1.178 | -2.734 | -0.67 | -1.74 |
19 | -0.103 | -0.193 | 0.603 | -0.809 |
20 | -0.429 | -0.043 | 0.43 | -0.158 |
P-value | Threshold |
---|---|
0.001 | 3.42236 |
0.0005 | 4.55416 |
0.0001 | 6.86796 |