| Motif | PAX7.H12INVIVO.2.PM.A |
| Gene (human) | PAX7 (GeneCards) |
| Gene synonyms (human) | HUP1 |
| Gene (mouse) | Pax7 |
| Gene synonyms (mouse) | Pax-7 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | A |
| Motif | PAX7.H12INVIVO.2.PM.A |
| Gene (human) | PAX7 (GeneCards) |
| Gene synonyms (human) | HUP1 |
| Gene (mouse) | Pax7 |
| Gene synonyms (mouse) | Pax-7 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | A |
| Motif length | 19 |
| Consensus | nhRMYYRATTAvbbdnvvn |
| GC content | 38.52% |
| Information content (bits; total / per base) | 11.5 / 0.605 |
| Data sources | ChIP-Seq + Methyl-HT-SELEX |
| Aligned words | 9881 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 3 (21) | 0.724 | 0.974 | 0.573 | 0.955 | 0.594 | 0.963 | 1.578 | 5.217 | 79.26 | 827.658 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.994 | 0.991 | 0.975 | 0.968 | 0.873 | 0.875 |
| best | 0.998 | 0.997 | 0.995 | 0.993 | 0.986 | 0.981 | |
| Methyl HT-SELEX, 2 experiments | median | 0.996 | 0.993 | 0.985 | 0.979 | 0.946 | 0.936 |
| best | 0.997 | 0.995 | 0.993 | 0.989 | 0.972 | 0.964 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.896 | 0.885 | 0.81 | 0.811 | 0.695 | 0.715 |
| best | 0.998 | 0.997 | 0.995 | 0.993 | 0.986 | 0.981 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.846 | 0.321 | 0.784 | 0.601 |
| batch 2 | 0.758 | 0.674 | 0.648 | 0.502 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Paired box factors {3.2} (TFClass) |
| TF family | PD+HD {3.2.1} (TFClass) |
| TF subfamily | PAX3-like {3.2.1.1} (TFClass) |
| TFClass ID | TFClass: 3.2.1.1.2 |
| HGNC | HGNC:8621 |
| MGI | MGI:97491 |
| EntrezGene (human) | GeneID:5081 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18509 (SSTAR profile) |
| UniProt ID (human) | PAX7_HUMAN |
| UniProt ID (mouse) | PAX7_MOUSE |
| UniProt AC (human) | P23759 (TFClass) |
| UniProt AC (mouse) | P47239 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 3 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | PAX7.H12INVIVO.2.PM.A.pcm |
| PWM | PAX7.H12INVIVO.2.PM.A.pwm |
| PFM | PAX7.H12INVIVO.2.PM.A.pfm |
| Alignment | PAX7.H12INVIVO.2.PM.A.words.tsv |
| Threshold to P-value map | PAX7.H12INVIVO.2.PM.A.thr |
| Motif in other formats | |
| JASPAR format | PAX7.H12INVIVO.2.PM.A_jaspar_format.txt |
| MEME format | PAX7.H12INVIVO.2.PM.A_meme_format.meme |
| Transfac format | PAX7.H12INVIVO.2.PM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2674.75 | 2453.75 | 2171.75 | 2580.75 |
| 02 | 1681.25 | 1957.25 | 1325.25 | 4917.25 |
| 03 | 5995.0 | 1245.0 | 1715.0 | 926.0 |
| 04 | 6027.0 | 1499.0 | 1464.0 | 891.0 |
| 05 | 557.0 | 1492.0 | 856.0 | 6976.0 |
| 06 | 258.0 | 4505.0 | 255.0 | 4863.0 |
| 07 | 5909.0 | 181.0 | 3773.0 | 18.0 |
| 08 | 9735.0 | 19.0 | 104.0 | 23.0 |
| 09 | 18.0 | 66.0 | 16.0 | 9781.0 |
| 10 | 101.0 | 224.0 | 80.0 | 9476.0 |
| 11 | 8933.0 | 213.0 | 533.0 | 202.0 |
| 12 | 1693.0 | 1483.0 | 5784.0 | 921.0 |
| 13 | 533.0 | 4151.0 | 1506.0 | 3691.0 |
| 14 | 1426.0 | 3545.0 | 3466.0 | 1444.0 |
| 15 | 3775.0 | 1518.0 | 1600.0 | 2988.0 |
| 16 | 1560.0 | 3515.0 | 2812.0 | 1994.0 |
| 17 | 2795.0 | 1591.0 | 3908.0 | 1587.0 |
| 18 | 1701.0 | 4250.0 | 2328.0 | 1602.0 |
| 19 | 2021.5 | 2489.5 | 2216.5 | 3153.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.271 | 0.248 | 0.22 | 0.261 |
| 02 | 0.17 | 0.198 | 0.134 | 0.498 |
| 03 | 0.607 | 0.126 | 0.174 | 0.094 |
| 04 | 0.61 | 0.152 | 0.148 | 0.09 |
| 05 | 0.056 | 0.151 | 0.087 | 0.706 |
| 06 | 0.026 | 0.456 | 0.026 | 0.492 |
| 07 | 0.598 | 0.018 | 0.382 | 0.002 |
| 08 | 0.985 | 0.002 | 0.011 | 0.002 |
| 09 | 0.002 | 0.007 | 0.002 | 0.99 |
| 10 | 0.01 | 0.023 | 0.008 | 0.959 |
| 11 | 0.904 | 0.022 | 0.054 | 0.02 |
| 12 | 0.171 | 0.15 | 0.585 | 0.093 |
| 13 | 0.054 | 0.42 | 0.152 | 0.374 |
| 14 | 0.144 | 0.359 | 0.351 | 0.146 |
| 15 | 0.382 | 0.154 | 0.162 | 0.302 |
| 16 | 0.158 | 0.356 | 0.285 | 0.202 |
| 17 | 0.283 | 0.161 | 0.396 | 0.161 |
| 18 | 0.172 | 0.43 | 0.236 | 0.162 |
| 19 | 0.205 | 0.252 | 0.224 | 0.319 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.079 | -0.007 | -0.129 | 0.044 |
| 02 | -0.384 | -0.233 | -0.622 | 0.688 |
| 03 | 0.886 | -0.684 | -0.364 | -0.98 |
| 04 | 0.891 | -0.499 | -0.523 | -1.018 |
| 05 | -1.486 | -0.504 | -1.058 | 1.038 |
| 06 | -2.251 | 0.6 | -2.263 | 0.677 |
| 07 | 0.872 | -2.602 | 0.423 | -4.802 |
| 08 | 1.371 | -4.754 | -3.147 | -4.582 |
| 09 | -4.802 | -3.589 | -4.906 | 1.375 |
| 10 | -3.175 | -2.391 | -3.403 | 1.344 |
| 11 | 1.285 | -2.441 | -1.53 | -2.493 |
| 12 | -0.377 | -0.51 | 0.85 | -0.985 |
| 13 | -1.53 | 0.519 | -0.494 | 0.401 |
| 14 | -0.549 | 0.361 | 0.338 | -0.536 |
| 15 | 0.424 | -0.486 | -0.434 | 0.19 |
| 16 | -0.459 | 0.352 | 0.129 | -0.214 |
| 17 | 0.123 | -0.439 | 0.458 | -0.442 |
| 18 | -0.373 | 0.542 | -0.059 | -0.433 |
| 19 | -0.2 | 0.008 | -0.108 | 0.244 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.28691 |
| 0.0005 | 5.30211 |
| 0.0001 | 7.30706 |