MotifPAX4.H12INVIVO.0.SM.D
Gene (human)PAX4
(GeneCards)
Gene synonyms (human)
Gene (mouse)Pax4
Gene synonyms (mouse)Pax-4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length9
ConsensusnvATTAvbn
GC content30.82%
Information content (bits; total / per base)7.757 / 0.862
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7431

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.727 0.683 0.65 0.624 0.583 0.58
best 0.968 0.951 0.935 0.909 0.877 0.848
Methyl HT-SELEX, 1 experiments median 0.968 0.951 0.935 0.909 0.877 0.848
best 0.968 0.951 0.935 0.909 0.877 0.848
Non-Methyl HT-SELEX, 5 experiments median 0.653 0.611 0.597 0.575 0.551 0.547
best 0.91 0.869 0.862 0.815 0.796 0.755
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classPaired box factors {3.2} (TFClass)
TF familyPD+HD {3.2.1} (TFClass)
TF subfamilyPAX4-like {3.2.1.2} (TFClass)
TFClass IDTFClass: 3.2.1.2.1
HGNCHGNC:8618
MGIMGI:97488
EntrezGene (human)
EntrezGene (mouse)GeneID:18506
(SSTAR profile)
UniProt ID (human)PAX4_HUMAN
UniProt ID (mouse)PAX4_MOUSE
UniProt AC (human)O43316
(TFClass)
UniProt AC (mouse)P32115
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
012024.01340.01663.02404.0
023686.51874.51566.5303.5
037027.0399.02.03.0
040.06.00.07425.0
0525.00.07.07399.0
066219.01212.00.00.0
072533.0946.03406.0546.0
08932.02633.01842.02024.0
091585.51701.52016.52127.5
PFM
ACGT
010.2720.180.2240.324
020.4960.2520.2110.041
030.9460.0540.00.0
040.00.0010.00.999
050.0030.00.0010.996
060.8370.1630.00.0
070.3410.1270.4580.073
080.1250.3540.2480.272
090.2130.2290.2710.286
PWM
ACGT
010.086-0.326-0.1110.257
020.6850.009-0.17-1.806
031.33-1.534-6.087-5.874
04-6.727-5.421-6.7271.385
05-4.224-6.727-5.3061.381
061.207-0.426-6.727-6.727
070.31-0.6740.606-1.222
08-0.6890.348-0.0090.086
09-0.158-0.0880.0820.135
Standard thresholds
P-value Threshold
0.001 5.61897
0.0005 6.081145
0.0001 6.751975