| Motif | PAX4.H12CORE.0.SM.B |
| Gene (human) | PAX4 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Pax4 |
| Gene synonyms (mouse) | Pax-4 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | PAX4.H12CORE.0.SM.B |
| Gene (human) | PAX4 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Pax4 |
| Gene synonyms (mouse) | Pax-4 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 9 |
| Consensus | nvATTAvbn |
| GC content | 30.82% |
| Information content (bits; total / per base) | 7.757 / 0.862 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 7431 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.727 | 0.683 | 0.65 | 0.624 | 0.583 | 0.58 |
| best | 0.968 | 0.951 | 0.935 | 0.909 | 0.877 | 0.848 | |
| Methyl HT-SELEX, 1 experiments | median | 0.968 | 0.951 | 0.935 | 0.909 | 0.877 | 0.848 |
| best | 0.968 | 0.951 | 0.935 | 0.909 | 0.877 | 0.848 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.653 | 0.611 | 0.597 | 0.575 | 0.551 | 0.547 |
| best | 0.91 | 0.869 | 0.862 | 0.815 | 0.796 | 0.755 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Paired box factors {3.2} (TFClass) |
| TF family | PD+HD {3.2.1} (TFClass) |
| TF subfamily | PAX4-like {3.2.1.2} (TFClass) |
| TFClass ID | TFClass: 3.2.1.2.1 |
| HGNC | HGNC:8618 |
| MGI | MGI:97488 |
| EntrezGene (human) | |
| EntrezGene (mouse) | GeneID:18506 (SSTAR profile) |
| UniProt ID (human) | PAX4_HUMAN |
| UniProt ID (mouse) | PAX4_MOUSE |
| UniProt AC (human) | O43316 (TFClass) |
| UniProt AC (mouse) | P32115 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | PAX4.H12CORE.0.SM.B.pcm |
| PWM | PAX4.H12CORE.0.SM.B.pwm |
| PFM | PAX4.H12CORE.0.SM.B.pfm |
| Alignment | PAX4.H12CORE.0.SM.B.words.tsv |
| Threshold to P-value map | PAX4.H12CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | PAX4.H12CORE.0.SM.B_jaspar_format.txt |
| MEME format | PAX4.H12CORE.0.SM.B_meme_format.meme |
| Transfac format | PAX4.H12CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2024.0 | 1340.0 | 1663.0 | 2404.0 |
| 02 | 3686.5 | 1874.5 | 1566.5 | 303.5 |
| 03 | 7027.0 | 399.0 | 2.0 | 3.0 |
| 04 | 0.0 | 6.0 | 0.0 | 7425.0 |
| 05 | 25.0 | 0.0 | 7.0 | 7399.0 |
| 06 | 6219.0 | 1212.0 | 0.0 | 0.0 |
| 07 | 2533.0 | 946.0 | 3406.0 | 546.0 |
| 08 | 932.0 | 2633.0 | 1842.0 | 2024.0 |
| 09 | 1585.5 | 1701.5 | 2016.5 | 2127.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.272 | 0.18 | 0.224 | 0.324 |
| 02 | 0.496 | 0.252 | 0.211 | 0.041 |
| 03 | 0.946 | 0.054 | 0.0 | 0.0 |
| 04 | 0.0 | 0.001 | 0.0 | 0.999 |
| 05 | 0.003 | 0.0 | 0.001 | 0.996 |
| 06 | 0.837 | 0.163 | 0.0 | 0.0 |
| 07 | 0.341 | 0.127 | 0.458 | 0.073 |
| 08 | 0.125 | 0.354 | 0.248 | 0.272 |
| 09 | 0.213 | 0.229 | 0.271 | 0.286 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.086 | -0.326 | -0.111 | 0.257 |
| 02 | 0.685 | 0.009 | -0.17 | -1.806 |
| 03 | 1.33 | -1.534 | -6.087 | -5.874 |
| 04 | -6.727 | -5.421 | -6.727 | 1.385 |
| 05 | -4.224 | -6.727 | -5.306 | 1.381 |
| 06 | 1.207 | -0.426 | -6.727 | -6.727 |
| 07 | 0.31 | -0.674 | 0.606 | -1.222 |
| 08 | -0.689 | 0.348 | -0.009 | 0.086 |
| 09 | -0.158 | -0.088 | 0.082 | 0.135 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.61897 |
| 0.0005 | 6.081145 |
| 0.0001 | 6.751975 |