MotifPAX3.H12INVIVO.3.S.B
Gene (human)PAX3
(GeneCards)
Gene synonyms (human)HUP2
Gene (mouse)Pax3
Gene synonyms (mouse)Pax-3
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
B
Motif length20
ConsensusnnTAATCGATTAvbnnnnnn
GC content30.45%
Information content (bits; total / per base)18.473 / 0.924
Data sourcesHT-SELEX
Aligned words2491

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (39) 0.544 0.697 0.4 0.65 0.43 0.665 1.095 3.195 25.569 210.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.987 0.982 0.911 0.9 0.781 0.794
best 0.999 0.999 0.983 0.982 0.811 0.815
Methyl HT-SELEX, 1 experiments median 0.986 0.981 0.902 0.891 0.792 0.785
best 0.986 0.981 0.902 0.891 0.792 0.785
Non-Methyl HT-SELEX, 3 experiments median 0.988 0.983 0.92 0.909 0.77 0.803
best 0.999 0.999 0.983 0.982 0.811 0.815
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classPaired box factors {3.2} (TFClass)
TF familyPD+HD {3.2.1} (TFClass)
TF subfamilyPAX3-like {3.2.1.1} (TFClass)
TFClass IDTFClass: 3.2.1.1.1
HGNCHGNC:8617
MGIMGI:97487
EntrezGene (human)GeneID:5077
(SSTAR profile)
EntrezGene (mouse)GeneID:18505
(SSTAR profile)
UniProt ID (human)PAX3_HUMAN
UniProt ID (mouse)PAX3_MOUSE
UniProt AC (human)P23760
(TFClass)
UniProt AC (mouse)P24610
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01646.0377.0895.0573.0
02380.25598.25594.25918.25
0370.035.015.02371.0
042484.03.04.00.0
052486.00.01.04.0
060.00.01.02490.0
070.01939.00.0552.0
08535.00.01956.00.0
092490.01.00.00.0
101.00.01.02489.0
116.06.03.02476.0
122394.013.055.029.0
131051.0536.0713.0191.0
14296.0768.0376.01051.0
15565.0561.0466.0899.0
16954.0454.0532.0551.0
17733.0532.0487.0739.0
18666.0680.0416.0729.0
19841.5645.5398.5605.5
20800.0692.0414.0585.0
PFM
ACGT
010.2590.1510.3590.23
020.1530.240.2390.369
030.0280.0140.0060.952
040.9970.0010.0020.0
050.9980.00.00.002
060.00.00.01.0
070.00.7780.00.222
080.2150.00.7850.0
091.00.00.00.0
100.00.00.00.999
110.0020.0020.0010.994
120.9610.0050.0220.012
130.4220.2150.2860.077
140.1190.3080.1510.422
150.2270.2250.1870.361
160.3830.1820.2140.221
170.2940.2140.1960.297
180.2670.2730.1670.293
190.3380.2590.160.243
200.3210.2780.1660.235
PWM
ACGT
010.037-0.50.362-0.083
02-0.491-0.04-0.0470.387
03-2.161-2.828-3.6071.335
041.381-4.837-4.653-5.767
051.382-5.767-5.354-4.653
06-5.767-5.767-5.3541.384
07-5.7671.134-5.767-0.12
08-0.151-5.7671.142-5.767
091.384-5.354-5.767-5.767
10-5.354-5.767-5.3541.383
11-4.363-4.363-4.8371.378
121.344-3.732-2.395-3.005
130.522-0.150.135-1.175
14-0.740.209-0.5030.522
15-0.097-0.104-0.2890.366
160.425-0.315-0.157-0.122
170.163-0.157-0.2450.171
180.0670.088-0.4020.157
190.30.036-0.445-0.028
200.250.105-0.407-0.062
Standard thresholds
P-value Threshold
0.001 -1.83774
0.0005 0.03186
0.0001 3.81831