MotifPAX3.H12CORE.2.P.C
Gene (human)PAX3
(GeneCards)
Gene synonyms (human)HUP2
Gene (mouse)Pax3
Gene synonyms (mouse)Pax-3
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length12
ConsensusWMYCAATTWnhn
GC content30.37%
Information content (bits; total / per base)9.614 / 0.801
Data sourcesChIP-Seq
Aligned words892

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (39) 0.602 0.75 0.464 0.694 0.56 0.768 1.483 3.194 37.77 183.244

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.974 0.963 0.909 0.89 0.8 0.798
best 0.998 0.996 0.976 0.973 0.818 0.82
Methyl HT-SELEX, 1 experiments median 0.978 0.97 0.91 0.893 0.814 0.799
best 0.978 0.97 0.91 0.893 0.814 0.799
Non-Methyl HT-SELEX, 3 experiments median 0.969 0.955 0.908 0.886 0.786 0.798
best 0.998 0.996 0.976 0.973 0.818 0.82
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classPaired box factors {3.2} (TFClass)
TF familyPD+HD {3.2.1} (TFClass)
TF subfamilyPAX3-like {3.2.1.1} (TFClass)
TFClass IDTFClass: 3.2.1.1.1
HGNCHGNC:8617
MGIMGI:97487
EntrezGene (human)GeneID:5077
(SSTAR profile)
EntrezGene (mouse)GeneID:18505
(SSTAR profile)
UniProt ID (human)PAX3_HUMAN
UniProt ID (mouse)PAX3_MOUSE
UniProt AC (human)P23760
(TFClass)
UniProt AC (mouse)P24610
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01679.063.073.077.0
02654.097.050.091.0
0342.0120.069.0661.0
0423.0742.075.052.0
05703.0133.045.011.0
06758.047.070.017.0
077.07.018.0860.0
086.037.0142.0707.0
09645.017.027.0203.0
10168.0255.0286.0183.0
11269.0342.0103.0178.0
12212.0297.0136.0247.0
PFM
ACGT
010.7610.0710.0820.086
020.7330.1090.0560.102
030.0470.1350.0770.741
040.0260.8320.0840.058
050.7880.1490.050.012
060.850.0530.0780.019
070.0080.0080.020.964
080.0070.0410.1590.793
090.7230.0190.030.228
100.1880.2860.3210.205
110.3020.3830.1150.2
120.2380.3330.1520.277
PWM
ACGT
011.108-1.245-1.101-1.049
021.071-0.823-1.469-0.885
03-1.637-0.613-1.1561.082
04-2.2081.197-1.075-1.431
051.143-0.512-1.571-2.873
061.218-1.529-1.142-2.486
07-3.252-3.252-2.4341.344
08-3.374-1.759-0.4471.149
091.057-2.486-2.058-0.093
10-0.2810.1330.247-0.196
110.1860.425-0.764-0.223
12-0.050.285-0.490.101
Standard thresholds
P-value Threshold
0.001 4.77486
0.0005 5.563215
0.0001 7.171625