MotifPAX2.H12INVIVO.0.SM.D
Gene (human)PAX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Pax2
Gene synonyms (mouse)Pax-2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length19
ConsensusvnbYRnTSAWGCGTRWMvn
GC content54.43%
Information content (bits; total / per base)13.929 / 0.733
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9956

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.998 0.997 0.996 0.994 0.93 0.935
best 1.0 1.0 1.0 0.999 0.998 0.997
Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 0.999 0.998 0.997
best 1.0 1.0 1.0 0.999 0.998 0.997
Non-Methyl HT-SELEX, 3 experiments median 0.996 0.994 0.993 0.988 0.877 0.894
best 1.0 1.0 0.999 0.999 0.982 0.975

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.685 0.389 0.557 0.375
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classPaired box factors {3.2} (TFClass)
TF familyPD {3.2.2} (TFClass)
TF subfamilyPAX2-like {3.2.2.2} (TFClass)
TFClass IDTFClass: 3.2.2.2.1
HGNCHGNC:8616
MGIMGI:97486
EntrezGene (human)GeneID:5076
(SSTAR profile)
EntrezGene (mouse)GeneID:18504
(SSTAR profile)
UniProt ID (human)PAX2_HUMAN
UniProt ID (mouse)PAX2_MOUSE
UniProt AC (human)Q02962
(TFClass)
UniProt AC (mouse)P32114
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012932.251173.255081.25769.25
023519.51920.52186.52329.5
03266.02905.02377.04408.0
04473.06578.0301.02604.0
055697.0540.03559.0160.0
062924.02580.02780.01672.0
0743.02374.0237.07302.0
08467.05867.03317.0305.0
098264.024.01565.0103.0
106805.0239.0116.02796.0
1113.01905.08016.022.0
1226.09778.089.063.0
131681.044.08039.0192.0
14195.0707.0888.08166.0
152786.0179.06190.0801.0
167816.0681.0651.0808.0
171813.07203.0424.0516.0
181419.753352.753936.751246.75
192860.752031.753125.751937.75
PFM
ACGT
010.2950.1180.510.077
020.3540.1930.220.234
030.0270.2920.2390.443
040.0480.6610.030.262
050.5720.0540.3570.016
060.2940.2590.2790.168
070.0040.2380.0240.733
080.0470.5890.3330.031
090.830.0020.1570.01
100.6840.0240.0120.281
110.0010.1910.8050.002
120.0030.9820.0090.006
130.1690.0040.8070.019
140.020.0710.0890.82
150.280.0180.6220.08
160.7850.0680.0650.081
170.1820.7230.0430.052
180.1430.3370.3950.125
190.2870.2040.3140.195
PWM
ACGT
010.164-0.7510.713-1.172
020.346-0.259-0.129-0.066
03-2.2280.154-0.0460.571
04-1.6570.971-2.1060.045
050.828-1.5250.357-2.731
060.1610.0360.11-0.397
07-4.007-0.047-2.3431.076
08-1.6690.8570.287-2.093
091.199-4.551-0.463-3.164
101.005-2.335-3.0470.116
11-5.093-0.2671.169-4.63
12-4.4781.368-3.306-3.642
13-0.392-3.9851.172-2.551
14-2.536-1.256-1.0291.187
150.113-2.620.911-1.132
161.144-1.294-1.339-1.123
17-0.3171.062-1.765-1.57
18-0.5610.2980.458-0.69
190.139-0.2030.228-0.25
Standard thresholds
P-value Threshold
0.001 3.42851
0.0005 4.53931
0.0001 6.82356