MotifP73.H12INVIVO.0.PS.A
Gene (human)TP73
(GeneCards)
Gene synonyms (human)P73
Gene (mouse)Tp73
Gene synonyms (mouse)P73, Trp73
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length19
ConsensusdRCWWGYhSWRRCWWGYhh
GC content53.62%
Information content (bits; total / per base)14.961 / 0.787
Data sourcesChIP-Seq + HT-SELEX
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.975 0.996 0.958 0.992 0.961 0.993 5.762 7.105 501.268 744.495

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.987 0.986 0.825 0.847
best 0.999 0.999 0.987 0.986 0.825 0.847
TF superclassImmunoglobulin fold {6} (TFClass)
TF classp53 domain factors {6.3} (TFClass)
TF familyp53-related {6.3.1} (TFClass)
TF subfamily {6.3.1.0} (TFClass)
TFClass IDTFClass: 6.3.1.0.3
HGNCHGNC:12003
MGIMGI:1336991
EntrezGene (human)GeneID:7161
(SSTAR profile)
EntrezGene (mouse)GeneID:22062
(SSTAR profile)
UniProt ID (human)P73_HUMAN
UniProt ID (mouse)P73_MOUSE
UniProt AC (human)O15350
(TFClass)
UniProt AC (mouse)Q9JJP2
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 0
PCM
ACGT
01221.070.0511.0198.0
02425.033.0438.0104.0
039.0937.021.033.0
04726.091.068.0115.0
05347.013.0107.0533.0
062.06.0987.05.0
0777.0449.08.0466.0
08155.0519.076.0250.0
0957.0722.0160.061.0
10654.0131.034.0181.0
11255.035.0650.060.0
12588.09.0345.058.0
135.0985.05.05.0
14575.0106.016.0303.0
15134.069.088.0709.0
1637.015.0942.06.0
1784.0450.022.0444.0
18157.0497.065.0281.0
19140.0398.0109.0353.0
PFM
ACGT
010.2210.070.5110.198
020.4250.0330.4380.104
030.0090.9370.0210.033
040.7260.0910.0680.115
050.3470.0130.1070.533
060.0020.0060.9870.005
070.0770.4490.0080.466
080.1550.5190.0760.25
090.0570.7220.160.061
100.6540.1310.0340.181
110.2550.0350.650.06
120.5880.0090.3450.058
130.0050.9850.0050.005
140.5750.1060.0160.303
150.1340.0690.0880.709
160.0370.0150.9420.006
170.0840.450.0220.444
180.1570.4970.0650.281
190.140.3980.1090.353
PWM
ACGT
01-0.122-1.2550.711-0.231
020.528-1.9810.558-0.867
03-3.1561.316-2.405-1.981
041.062-0.999-1.284-0.769
050.326-2.839-0.840.753
06-4.213-3.4841.368-3.622
07-1.1620.583-3.2530.62
08-0.4740.727-1.1750.0
09-1.4551.056-0.442-1.39
100.957-0.64-1.952-0.32
110.02-1.9250.951-1.406
120.851-3.1560.32-1.439
13-3.6221.366-3.622-3.622
140.829-0.849-2.6530.191
15-0.618-1.27-1.0321.038
16-1.872-2.7111.321-3.484
17-1.0770.585-2.3620.571
18-0.4610.684-1.3280.116
19-0.5740.462-0.8210.343
Standard thresholds
P-value Threshold
0.001 3.12721
0.0005 4.26101
0.0001 6.62331