P73.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	P73.H12INVIVO.0.PS.A
Gene (human)	TP73 (GeneCards)
Gene synonyms (human)	P73
Gene (mouse)	Tp73
Gene synonyms (mouse)	P73, Trp73
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	19
Consensus	dRCWWGYhSWRRCWWGYhh
GC content	53.62%
Information content (bits; total / per base)	14.961 / 0.787
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.975	0.996	0.958	0.992	0.961	0.993	5.762	7.105	501.268	744.495

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.987	0.986	0.825	0.847
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.987	0.986	0.825	0.847

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	p53 domain factors {6.3} (TFClass)
TF family	p53-related {6.3.1} (TFClass)
TF subfamily	{6.3.1.0} (TFClass)
TFClass ID	TFClass: 6.3.1.0.3
HGNC	HGNC:12003
MGI	MGI:1336991
EntrezGene (human)	GeneID:7161 (SSTAR profile)
EntrezGene (mouse)	GeneID:22062 (SSTAR profile)
UniProt ID (human)	P73_HUMAN
UniProt ID (mouse)	P73_MOUSE
UniProt AC (human)	O15350 (TFClass)
UniProt AC (mouse)	Q9JJP2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	P73.H12INVIVO.0.PS.A.pcm
PWM	P73.H12INVIVO.0.PS.A.pwm
PFM	P73.H12INVIVO.0.PS.A.pfm
Alignment	P73.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	P73.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	P73.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	P73.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	P73.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	P73.H12INVIVO.0.PS.A_homer_format_0.001.txt P73.H12INVIVO.0.PS.A_homer_format_0.0005.txt P73.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	221.0	70.0	511.0	198.0
02	425.0	33.0	438.0	104.0
03	9.0	937.0	21.0	33.0
04	726.0	91.0	68.0	115.0
05	347.0	13.0	107.0	533.0
06	2.0	6.0	987.0	5.0
07	77.0	449.0	8.0	466.0
08	155.0	519.0	76.0	250.0
09	57.0	722.0	160.0	61.0
10	654.0	131.0	34.0	181.0
11	255.0	35.0	650.0	60.0
12	588.0	9.0	345.0	58.0
13	5.0	985.0	5.0	5.0
14	575.0	106.0	16.0	303.0
15	134.0	69.0	88.0	709.0
16	37.0	15.0	942.0	6.0
17	84.0	450.0	22.0	444.0
18	157.0	497.0	65.0	281.0
19	140.0	398.0	109.0	353.0

PFM

	A	C	G	T
01	0.221	0.07	0.511	0.198
02	0.425	0.033	0.438	0.104
03	0.009	0.937	0.021	0.033
04	0.726	0.091	0.068	0.115
05	0.347	0.013	0.107	0.533
06	0.002	0.006	0.987	0.005
07	0.077	0.449	0.008	0.466
08	0.155	0.519	0.076	0.25
09	0.057	0.722	0.16	0.061
10	0.654	0.131	0.034	0.181
11	0.255	0.035	0.65	0.06
12	0.588	0.009	0.345	0.058
13	0.005	0.985	0.005	0.005
14	0.575	0.106	0.016	0.303
15	0.134	0.069	0.088	0.709
16	0.037	0.015	0.942	0.006
17	0.084	0.45	0.022	0.444
18	0.157	0.497	0.065	0.281
19	0.14	0.398	0.109	0.353

PWM

	A	C	G	T
01	-0.122	-1.255	0.711	-0.231
02	0.528	-1.981	0.558	-0.867
03	-3.156	1.316	-2.405	-1.981
04	1.062	-0.999	-1.284	-0.769
05	0.326	-2.839	-0.84	0.753
06	-4.213	-3.484	1.368	-3.622
07	-1.162	0.583	-3.253	0.62
08	-0.474	0.727	-1.175	0.0
09	-1.455	1.056	-0.442	-1.39
10	0.957	-0.64	-1.952	-0.32
11	0.02	-1.925	0.951	-1.406
12	0.851	-3.156	0.32	-1.439
13	-3.622	1.366	-3.622	-3.622
14	0.829	-0.849	-2.653	0.191
15	-0.618	-1.27	-1.032	1.038
16	-1.872	-2.711	1.321	-3.484
17	-1.077	0.585	-2.362	0.571
18	-0.461	0.684	-1.328	0.116
19	-0.574	0.462	-0.821	0.343

Standard thresholds

P-value	Threshold
0.001	3.12721
0.0005	4.26101
0.0001	6.62331