MotifP73.H12INVITRO.1.P.B
Gene (human)TP73
(GeneCards)
Gene synonyms (human)P73
Gene (mouse)Tp73
Gene synonyms (mouse)P73, Trp73
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensushhRGRCWTGYh
GC content53.14%
Information content (bits; total / per base)9.889 / 0.899
Data sourcesChIP-Seq
Aligned words984

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.878 0.933 0.79 0.871 0.816 0.879 2.649 3.281 289.721 512.658

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 1 experiments median 0.972 0.959 0.916 0.896 0.766 0.775
best 0.972 0.959 0.916 0.896 0.766 0.775
TF superclassImmunoglobulin fold {6} (TFClass)
TF classp53 domain factors {6.3} (TFClass)
TF familyp53-related {6.3.1} (TFClass)
TF subfamily {6.3.1.0} (TFClass)
TFClass IDTFClass: 6.3.1.0.3
HGNCHGNC:12003
MGIMGI:1336991
EntrezGene (human)GeneID:7161
(SSTAR profile)
EntrezGene (mouse)GeneID:22062
(SSTAR profile)
UniProt ID (human)P73_HUMAN
UniProt ID (mouse)P73_MOUSE
UniProt AC (human)O15350
(TFClass)
UniProt AC (mouse)Q9JJP2
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 0
PCM
ACGT
01150.0517.058.0259.0
02127.0453.0124.0280.0
03523.06.0327.0128.0
0463.08.0883.030.0
05411.07.0552.014.0
0614.0958.09.03.0
07637.057.037.0253.0
08116.014.029.0825.0
095.015.0958.06.0
1048.0313.04.0619.0
11143.0349.074.0418.0
PFM
ACGT
010.1520.5250.0590.263
020.1290.460.1260.285
030.5320.0060.3320.13
040.0640.0080.8970.03
050.4180.0070.5610.014
060.0140.9740.0090.003
070.6470.0580.0380.257
080.1180.0140.0290.838
090.0050.0150.9740.006
100.0490.3180.0040.629
110.1450.3550.0750.425
PWM
ACGT
01-0.490.739-1.4230.051
02-0.6550.607-0.6780.129
030.751-3.4680.283-0.647
04-1.342-3.2381.273-2.055
050.51-3.3460.804-2.757
06-2.7571.354-3.14-3.96
070.947-1.439-1.8560.028
08-0.744-2.757-2.0871.205
09-3.607-2.6961.354-3.468
10-1.6060.239-3.7680.919
11-0.5370.348-1.1850.527
Standard thresholds
P-value Threshold
0.001 4.78085
0.0005 5.658785
0.0001 7.431975