P73.H12CORE.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	P73.H12CORE.1.P.B
Gene (human)	TP73 (GeneCards)
Gene synonyms (human)	P73
Gene (mouse)	Tp73
Gene synonyms (mouse)	P73, Trp73
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	hhRGRCWTGYh
GC content	53.14%
Information content (bits; total / per base)	9.889 / 0.899
Data sources	ChIP-Seq
Aligned words	984

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.878	0.933	0.79	0.871	0.816	0.879	2.649	3.281	289.721	512.658

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.972	0.959	0.916	0.896	0.766	0.775
Non-Methyl HT-SELEX, 1 experiments	best	0.972	0.959	0.916	0.896	0.766	0.775

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	p53 domain factors {6.3} (TFClass)
TF family	p53-related {6.3.1} (TFClass)
TF subfamily	{6.3.1.0} (TFClass)
TFClass ID	TFClass: 6.3.1.0.3
HGNC	HGNC:12003
MGI	MGI:1336991
EntrezGene (human)	GeneID:7161 (SSTAR profile)
EntrezGene (mouse)	GeneID:22062 (SSTAR profile)
UniProt ID (human)	P73_HUMAN
UniProt ID (mouse)	P73_MOUSE
UniProt AC (human)	O15350 (TFClass)
UniProt AC (mouse)	Q9JJP2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	P73.H12CORE.1.P.B.pcm
PWM	P73.H12CORE.1.P.B.pwm
PFM	P73.H12CORE.1.P.B.pfm
Alignment	P73.H12CORE.1.P.B.words.tsv
Threshold to P-value map	P73.H12CORE.1.P.B.thr
Motif in other formats
JASPAR format	P73.H12CORE.1.P.B_jaspar_format.txt
MEME format	P73.H12CORE.1.P.B_meme_format.meme
Transfac format	P73.H12CORE.1.P.B_transfac_format.txt
Homer format	P73.H12CORE.1.P.B_homer_format_0.001.txt P73.H12CORE.1.P.B_homer_format_0.0005.txt P73.H12CORE.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	150.0	517.0	58.0	259.0
02	127.0	453.0	124.0	280.0
03	523.0	6.0	327.0	128.0
04	63.0	8.0	883.0	30.0
05	411.0	7.0	552.0	14.0
06	14.0	958.0	9.0	3.0
07	637.0	57.0	37.0	253.0
08	116.0	14.0	29.0	825.0
09	5.0	15.0	958.0	6.0
10	48.0	313.0	4.0	619.0
11	143.0	349.0	74.0	418.0

PFM

	A	C	G	T
01	0.152	0.525	0.059	0.263
02	0.129	0.46	0.126	0.285
03	0.532	0.006	0.332	0.13
04	0.064	0.008	0.897	0.03
05	0.418	0.007	0.561	0.014
06	0.014	0.974	0.009	0.003
07	0.647	0.058	0.038	0.257
08	0.118	0.014	0.029	0.838
09	0.005	0.015	0.974	0.006
10	0.049	0.318	0.004	0.629
11	0.145	0.355	0.075	0.425

PWM

	A	C	G	T
01	-0.49	0.739	-1.423	0.051
02	-0.655	0.607	-0.678	0.129
03	0.751	-3.468	0.283	-0.647
04	-1.342	-3.238	1.273	-2.055
05	0.51	-3.346	0.804	-2.757
06	-2.757	1.354	-3.14	-3.96
07	0.947	-1.439	-1.856	0.028
08	-0.744	-2.757	-2.087	1.205
09	-3.607	-2.696	1.354	-3.468
10	-1.606	0.239	-3.768	0.919
11	-0.537	0.348	-1.185	0.527

Standard thresholds

P-value	Threshold
0.001	4.78085
0.0005	5.658785
0.0001	7.431975