| Motif | P63.H12INVITRO.1.PS.A |
| Gene (human) | TP63 (GeneCards) |
| Gene synonyms (human) | KET, P63, P73H, P73L, TP73L |
| Gene (mouse) | Tp63 |
| Gene synonyms (mouse) | P63, P73l, Tp73l, Trp63 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | A |
| Motif | P63.H12INVITRO.1.PS.A |
| Gene (human) | TP63 (GeneCards) |
| Gene synonyms (human) | KET, P63, P73H, P73L, TP73L |
| Gene (mouse) | Tp63 |
| Gene synonyms (mouse) | P63, P73l, Tp73l, Trp63 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | A |
| Motif length | 9 |
| Consensus | ndYATGKhn |
| GC content | 43.05% |
| Information content (bits; total / per base) | 7.388 / 0.821 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 7381 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 41 (268) | 0.663 | 0.79 | 0.517 | 0.656 | 0.618 | 0.759 | 1.526 | 2.155 | 98.569 | 281.745 |
| Mouse | 3 (16) | 0.575 | 0.66 | 0.405 | 0.507 | 0.517 | 0.63 | 1.125 | 1.592 | 16.456 | 25.066 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 1 experiments | median | 0.682 | 0.656 | 0.628 | 0.604 | 0.589 | 0.573 |
| best | 0.682 | 0.656 | 0.628 | 0.604 | 0.589 | 0.573 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 2.766 | 11.405 | 0.212 | 0.169 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | p53 domain factors {6.3} (TFClass) |
| TF family | p53-related {6.3.1} (TFClass) |
| TF subfamily | {6.3.1.0} (TFClass) |
| TFClass ID | TFClass: 6.3.1.0.2 |
| HGNC | HGNC:15979 |
| MGI | MGI:1330810 |
| EntrezGene (human) | GeneID:8626 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:22061 (SSTAR profile) |
| UniProt ID (human) | P63_HUMAN |
| UniProt ID (mouse) | P63_MOUSE |
| UniProt AC (human) | Q9H3D4 (TFClass) |
| UniProt AC (mouse) | O88898 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 41 human, 3 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 0 |
| PCM | P63.H12INVITRO.1.PS.A.pcm |
| PWM | P63.H12INVITRO.1.PS.A.pwm |
| PFM | P63.H12INVITRO.1.PS.A.pfm |
| Alignment | P63.H12INVITRO.1.PS.A.words.tsv |
| Threshold to P-value map | P63.H12INVITRO.1.PS.A.thr |
| Motif in other formats | |
| JASPAR format | P63.H12INVITRO.1.PS.A_jaspar_format.txt |
| MEME format | P63.H12INVITRO.1.PS.A_meme_format.meme |
| Transfac format | P63.H12INVITRO.1.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1702.0 | 1769.0 | 2286.0 | 1624.0 |
| 02 | 2822.25 | 706.25 | 2292.25 | 1560.25 |
| 03 | 501.0 | 5858.0 | 272.0 | 750.0 |
| 04 | 7381.0 | 0.0 | 0.0 | 0.0 |
| 05 | 1874.0 | 124.0 | 0.0 | 5383.0 |
| 06 | 0.0 | 0.0 | 7381.0 | 0.0 |
| 07 | 8.0 | 244.0 | 1999.0 | 5130.0 |
| 08 | 1775.25 | 1657.25 | 589.25 | 3359.25 |
| 09 | 2435.5 | 1989.5 | 1433.5 | 1522.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.231 | 0.24 | 0.31 | 0.22 |
| 02 | 0.382 | 0.096 | 0.311 | 0.211 |
| 03 | 0.068 | 0.794 | 0.037 | 0.102 |
| 04 | 1.0 | 0.0 | 0.0 | 0.0 |
| 05 | 0.254 | 0.017 | 0.0 | 0.729 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.001 | 0.033 | 0.271 | 0.695 |
| 08 | 0.241 | 0.225 | 0.08 | 0.455 |
| 09 | 0.33 | 0.27 | 0.194 | 0.206 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.081 | -0.042 | 0.214 | -0.128 |
| 02 | 0.425 | -0.958 | 0.217 | -0.168 |
| 03 | -1.301 | 1.154 | -1.908 | -0.899 |
| 04 | 1.385 | -6.721 | -6.721 | -6.721 |
| 05 | 0.015 | -2.683 | -6.721 | 1.07 |
| 06 | -6.721 | -6.721 | 1.385 | -6.721 |
| 07 | -5.197 | -2.015 | 0.08 | 1.022 |
| 08 | -0.039 | -0.107 | -1.139 | 0.599 |
| 09 | 0.277 | 0.075 | -0.252 | -0.192 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.45108 |
| 0.0005 | 5.991965 |
| 0.0001 | 6.730165 |