| Motif | P53.H12RSNP.1.S.C |
| Gene (human) | TP53 (GeneCards) |
| Gene synonyms (human) | P53 |
| Gene (mouse) | Tp53 |
| Gene synonyms (mouse) | P53, Trp53 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | C |
| Motif | P53.H12RSNP.1.S.C |
| Gene (human) | TP53 (GeneCards) |
| Gene synonyms (human) | P53 |
| Gene (mouse) | Tp53 |
| Gene synonyms (mouse) | P53, Trp53 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | C |
| Motif length | 9 |
| Consensus | nCATGThhn |
| GC content | 44.16% |
| Information content (bits; total / per base) | 9.195 / 1.022 |
| Data sources | HT-SELEX |
| Aligned words | 6139 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 97 (581) | 0.816 | 0.932 | 0.738 | 0.878 | 0.766 | 0.873 | 2.286 | 2.939 | 194.456 | 660.114 |
| Mouse | 15 (101) | 0.811 | 0.916 | 0.709 | 0.877 | 0.762 | 0.892 | 2.462 | 3.879 | 229.658 | 436.495 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 1 experiments | median | 0.712 | 0.668 | 0.641 | 0.613 | 0.593 | 0.578 |
| best | 0.712 | 0.668 | 0.641 | 0.613 | 0.593 | 0.578 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 7.13 | 2.664 | 0.016 | -0.0 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | p53 domain factors {6.3} (TFClass) |
| TF family | p53-related {6.3.1} (TFClass) |
| TF subfamily | {6.3.1.0} (TFClass) |
| TFClass ID | TFClass: 6.3.1.0.1 |
| HGNC | HGNC:11998 |
| MGI | MGI:98834 |
| EntrezGene (human) | GeneID:7157 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:22059 (SSTAR profile) |
| UniProt ID (human) | P53_HUMAN |
| UniProt ID (mouse) | P53_MOUSE |
| UniProt AC (human) | P04637 (TFClass) |
| UniProt AC (mouse) | P02340 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 97 human, 15 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 0 |
| PCM | P53.H12RSNP.1.S.C.pcm |
| PWM | P53.H12RSNP.1.S.C.pwm |
| PFM | P53.H12RSNP.1.S.C.pfm |
| Alignment | P53.H12RSNP.1.S.C.words.tsv |
| Threshold to P-value map | P53.H12RSNP.1.S.C.thr |
| Motif in other formats | |
| JASPAR format | P53.H12RSNP.1.S.C_jaspar_format.txt |
| MEME format | P53.H12RSNP.1.S.C_meme_format.meme |
| Transfac format | P53.H12RSNP.1.S.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1965.25 | 826.25 | 1828.25 | 1519.25 |
| 02 | 97.0 | 5888.0 | 39.0 | 115.0 |
| 03 | 5206.0 | 8.0 | 33.0 | 892.0 |
| 04 | 48.0 | 5.0 | 0.0 | 6086.0 |
| 05 | 0.0 | 0.0 | 6139.0 | 0.0 |
| 06 | 0.0 | 531.0 | 0.0 | 5608.0 |
| 07 | 940.0 | 2582.0 | 199.0 | 2418.0 |
| 08 | 1121.0 | 2736.0 | 489.0 | 1793.0 |
| 09 | 1447.5 | 1480.5 | 1616.5 | 1594.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.32 | 0.135 | 0.298 | 0.247 |
| 02 | 0.016 | 0.959 | 0.006 | 0.019 |
| 03 | 0.848 | 0.001 | 0.005 | 0.145 |
| 04 | 0.008 | 0.001 | 0.0 | 0.991 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 0.0 | 0.086 | 0.0 | 0.914 |
| 07 | 0.153 | 0.421 | 0.032 | 0.394 |
| 08 | 0.183 | 0.446 | 0.08 | 0.292 |
| 09 | 0.236 | 0.241 | 0.263 | 0.26 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.247 | -0.618 | 0.175 | -0.01 |
| 02 | -2.741 | 1.343 | -3.62 | -2.574 |
| 03 | 1.22 | -5.017 | -3.777 | -0.542 |
| 04 | -3.422 | -5.366 | -6.558 | 1.377 |
| 05 | -6.558 | -6.558 | 1.385 | -6.558 |
| 06 | -6.558 | -1.059 | -6.558 | 1.295 |
| 07 | -0.489 | 0.52 | -2.033 | 0.454 |
| 08 | -0.314 | 0.578 | -1.141 | 0.155 |
| 09 | -0.058 | -0.036 | 0.052 | 0.038 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.26491 |
| 0.0005 | 6.16536 |
| 0.0001 | 7.528725 |