MotifOVOL2.H12INVIVO.0.PSM.A
Gene (human)OVOL2
(GeneCards)
Gene synonyms (human)ZNF339
Gene (mouse)Ovol2
Gene synonyms (mouse)Ovo2, Zfp339, Znf339
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length13
ConsensusndnvTAACGGWhn
GC content41.62%
Information content (bits; total / per base)13.182 / 1.014
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9714

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.96 0.972 0.923 0.944 0.91 0.933 3.735 4.007 463.854 482.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.998 0.996 0.996 0.993 0.989 0.985
best 0.998 0.997 0.998 0.996 0.996 0.994
Methyl HT-SELEX, 2 experiments median 0.997 0.994 0.994 0.99 0.965 0.961
best 0.997 0.995 0.996 0.993 0.986 0.982
Non-Methyl HT-SELEX, 2 experiments median 0.998 0.996 0.997 0.995 0.994 0.991
best 0.998 0.997 0.998 0.996 0.996 0.994

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.744 0.415 0.842 0.705
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyOVOL {2.3.3.17} (TFClass)
TFClass IDTFClass: 2.3.3.17.2
HGNCHGNC:15804
MGIMGI:1338039
EntrezGene (human)GeneID:58495
(SSTAR profile)
EntrezGene (mouse)GeneID:107586
(SSTAR profile)
UniProt ID (human)OVOL2_HUMAN
UniProt ID (mouse)OVOL2_MOUSE
UniProt AC (human)Q9BRP0
(TFClass)
UniProt AC (mouse)Q8CIV7
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
012335.752200.752371.752805.75
024381.0991.02452.01890.0
032277.02195.02312.02930.0
045324.01844.01788.0758.0
056.036.07.09665.0
069714.00.00.00.0
079708.00.06.00.0
080.09714.00.00.0
090.00.09714.00.0
100.05.09689.020.0
113656.0543.0581.04934.0
124127.51366.51321.52898.5
132928.751938.751476.753369.75
PFM
ACGT
010.240.2270.2440.289
020.4510.1020.2520.195
030.2340.2260.2380.302
040.5480.190.1840.078
050.0010.0040.0010.995
061.00.00.00.0
070.9990.00.0010.0
080.01.00.00.0
090.00.01.00.0
100.00.0010.9970.002
110.3760.0560.060.508
120.4250.1410.1360.298
130.3010.20.1520.347
PWM
ACGT
01-0.039-0.098-0.0240.144
020.59-0.8950.01-0.25
03-0.064-0.101-0.0490.188
040.784-0.275-0.306-1.162
05-5.68-4.151-5.5661.381
061.386-6.965-6.965-6.965
071.385-6.965-5.68-6.965
08-6.9651.386-6.965-6.965
09-6.965-6.9651.386-6.965
10-6.965-5.8091.383-4.692
110.409-1.495-1.4270.708
120.53-0.574-0.6080.177
130.187-0.225-0.4970.327
Standard thresholds
P-value Threshold
0.001 1.16441
0.0005 2.28586
0.0001 7.67336