OVOL1.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	OVOL1.H12INVIVO.0.SM.D
Gene (human)	OVOL1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ovol1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	14
Consensus	nRnATAACGGThhn
GC content	42.17%
Information content (bits; total / per base)	15.713 / 1.122
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9850

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	1.0	0.999	0.999	0.999	0.999	0.998
Overall, 2 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.999	0.999	0.999	0.998
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.999	0.999	0.999	0.998

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.983	0.906	0.965	0.64
batch 2	0.85	0.668	0.766	0.567

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	OVOL {2.3.3.17} (TFClass)
TFClass ID	TFClass: 2.3.3.17.1
HGNC	HGNC:8525
MGI	MGI:1330290
EntrezGene (human)	GeneID:5017 (SSTAR profile)
EntrezGene (mouse)	GeneID:18426 (SSTAR profile)
UniProt ID (human)	OVOL1_HUMAN
UniProt ID (mouse)	OVOL1_MOUSE
UniProt AC (human)	O14753 (TFClass)
UniProt AC (mouse)	Q9WTJ2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	OVOL1.H12INVIVO.0.SM.D.pcm
PWM	OVOL1.H12INVIVO.0.SM.D.pwm
PFM	OVOL1.H12INVIVO.0.SM.D.pfm
Alignment	OVOL1.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	OVOL1.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	OVOL1.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	OVOL1.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	OVOL1.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	OVOL1.H12INVIVO.0.SM.D_homer_format_0.001.txt OVOL1.H12INVIVO.0.SM.D_homer_format_0.0005.txt OVOL1.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1961.75	2731.75	3052.75	2103.75
02	4840.25	404.25	3559.25	1046.25
03	2767.0	2239.0	2561.0	2283.0
04	8260.0	649.0	860.0	81.0
05	2.0	4.0	3.0	9841.0
06	9850.0	0.0	0.0	0.0
07	9850.0	0.0	0.0	0.0
08	0.0	9850.0	0.0	0.0
09	2.0	5.0	9842.0	1.0
10	1.0	1.0	9846.0	2.0
11	411.0	62.0	195.0	9182.0
12	2820.0	3019.0	534.0	3477.0
13	1760.25	3970.25	427.25	3692.25
14	2057.0	2691.0	1646.0	3456.0

PFM

	A	C	G	T
01	0.199	0.277	0.31	0.214
02	0.491	0.041	0.361	0.106
03	0.281	0.227	0.26	0.232
04	0.839	0.066	0.087	0.008
05	0.0	0.0	0.0	0.999
06	1.0	0.0	0.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.001	0.999	0.0
10	0.0	0.0	1.0	0.0
11	0.042	0.006	0.02	0.932
12	0.286	0.306	0.054	0.353
13	0.179	0.403	0.043	0.375
14	0.209	0.273	0.167	0.351

PWM

	A	C	G	T
01	-0.227	0.104	0.215	-0.157
02	0.675	-1.802	0.368	-0.855
03	0.116	-0.095	0.039	-0.076
04	1.21	-1.331	-1.05	-3.387
05	-6.352	-5.97	-6.142	1.385
06	1.386	-6.977	-6.977	-6.977
07	1.386	-6.977	-6.977	-6.977
08	-6.977	1.386	-6.977	-6.977
09	-6.352	-5.822	1.385	-6.616
10	-6.616	-6.616	1.385	-6.352
11	-1.786	-3.646	-2.525	1.315
12	0.135	0.204	-1.525	0.345
13	-0.335	0.477	-1.747	0.405
14	-0.18	0.089	-0.402	0.339

Standard thresholds

P-value	Threshold
0.001	-0.65114
0.0005	1.18541
0.0001	5.14071