MotifOTX1.H12INVIVO.0.SM.D
Gene (human)OTX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Otx1
Gene synonyms (mouse)Otx-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length12
ConsensusdnvSGATTAdnn
GC content41.44%
Information content (bits; total / per base)11.282 / 0.94
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8976

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.948 0.91 0.922 0.884 0.858 0.824
best 0.99 0.983 0.984 0.974 0.967 0.953
Methyl HT-SELEX, 3 experiments median 0.945 0.904 0.928 0.886 0.883 0.841
best 0.989 0.98 0.984 0.973 0.952 0.939
Non-Methyl HT-SELEX, 7 experiments median 0.951 0.916 0.917 0.883 0.833 0.807
best 0.99 0.983 0.984 0.974 0.967 0.953

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.996 0.929 0.966 0.558
batch 2 0.852 0.72 0.889 0.696
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyOTX {3.1.3.17} (TFClass)
TFClass IDTFClass: 3.1.3.17.1
HGNCHGNC:8521
MGIMGI:97450
EntrezGene (human)GeneID:5013
(SSTAR profile)
EntrezGene (mouse)GeneID:18423
(SSTAR profile)
UniProt ID (human)OTX1_HUMAN
UniProt ID (mouse)OTX1_MOUSE
UniProt AC (human)P32242
(TFClass)
UniProt AC (mouse)P80205
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
013910.51623.51699.51742.5
021844.01713.02947.02472.0
031476.04578.02068.0854.0
04891.0943.06941.0201.0
050.02.08974.00.0
068704.0272.00.00.0
070.00.00.08976.0
082.00.00.08974.0
098915.00.07.054.0
104142.01108.02042.01684.0
111631.252410.252716.252218.25
122153.51884.52702.52235.5
PFM
ACGT
010.4360.1810.1890.194
020.2050.1910.3280.275
030.1640.510.230.095
040.0990.1050.7730.022
050.00.01.00.0
060.970.030.00.0
070.00.00.01.0
080.00.00.01.0
090.9930.00.0010.006
100.4610.1230.2270.188
110.1820.2690.3030.247
120.240.210.3010.249
PWM
ACGT
010.555-0.323-0.278-0.253
02-0.196-0.270.2720.097
03-0.4180.712-0.082-0.964
04-0.922-0.8661.129-2.402
05-6.895-6.2641.385-6.895
061.355-2.103-6.895-6.895
07-6.895-6.895-6.8951.386
08-6.264-6.895-6.8951.385
091.379-6.895-5.49-3.687
100.612-0.705-0.094-0.287
11-0.3190.0710.191-0.012
12-0.041-0.1740.186-0.004
Standard thresholds
P-value Threshold
0.001 4.00628
0.0005 5.60162
0.0001 7.821405