| Motif | OTX1.H12INVITRO.0.SM.B |
| Gene (human) | OTX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Otx1 |
| Gene synonyms (mouse) | Otx-1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | OTX1.H12INVITRO.0.SM.B |
| Gene (human) | OTX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Otx1 |
| Gene synonyms (mouse) | Otx-1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 10 |
| Consensus | nvGATTAnbn |
| GC content | 41.95% |
| Information content (bits; total / per base) | 8.74 / 0.874 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9588 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 10 experiments | median | 0.952 | 0.918 | 0.928 | 0.892 | 0.869 | 0.836 |
| best | 0.992 | 0.989 | 0.985 | 0.977 | 0.965 | 0.95 | |
| Methyl HT-SELEX, 3 experiments | median | 0.948 | 0.912 | 0.934 | 0.894 | 0.895 | 0.855 |
| best | 0.992 | 0.989 | 0.985 | 0.977 | 0.956 | 0.945 | |
| Non-Methyl HT-SELEX, 7 experiments | median | 0.955 | 0.924 | 0.923 | 0.89 | 0.842 | 0.816 |
| best | 0.989 | 0.983 | 0.982 | 0.972 | 0.965 | 0.95 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.986 | 0.853 | 0.94 | 0.578 |
| batch 2 | 0.833 | 0.68 | 0.859 | 0.664 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | Paired-related HD {3.1.3} (TFClass) |
| TF subfamily | OTX {3.1.3.17} (TFClass) |
| TFClass ID | TFClass: 3.1.3.17.1 |
| HGNC | HGNC:8521 |
| MGI | MGI:97450 |
| EntrezGene (human) | GeneID:5013 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18423 (SSTAR profile) |
| UniProt ID (human) | OTX1_HUMAN |
| UniProt ID (mouse) | OTX1_MOUSE |
| UniProt AC (human) | P32242 (TFClass) |
| UniProt AC (mouse) | P80205 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 7 |
| Methyl-HT-SELEX | 3 |
| PCM | OTX1.H12INVITRO.0.SM.B.pcm |
| PWM | OTX1.H12INVITRO.0.SM.B.pwm |
| PFM | OTX1.H12INVITRO.0.SM.B.pfm |
| Alignment | OTX1.H12INVITRO.0.SM.B.words.tsv |
| Threshold to P-value map | OTX1.H12INVITRO.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | OTX1.H12INVITRO.0.SM.B_jaspar_format.txt |
| MEME format | OTX1.H12INVITRO.0.SM.B_meme_format.meme |
| Transfac format | OTX1.H12INVITRO.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2535.5 | 2763.5 | 2621.5 | 1667.5 |
| 02 | 2233.0 | 1316.0 | 4888.0 | 1151.0 |
| 03 | 240.0 | 137.0 | 9186.0 | 25.0 |
| 04 | 6322.0 | 3264.0 | 0.0 | 2.0 |
| 05 | 0.0 | 0.0 | 0.0 | 9588.0 |
| 06 | 0.0 | 313.0 | 0.0 | 9275.0 |
| 07 | 9200.0 | 5.0 | 71.0 | 312.0 |
| 08 | 3651.0 | 1793.0 | 2520.0 | 1624.0 |
| 09 | 1242.25 | 3286.25 | 3097.25 | 1962.25 |
| 10 | 2088.0 | 2440.0 | 2523.0 | 2537.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.264 | 0.288 | 0.273 | 0.174 |
| 02 | 0.233 | 0.137 | 0.51 | 0.12 |
| 03 | 0.025 | 0.014 | 0.958 | 0.003 |
| 04 | 0.659 | 0.34 | 0.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.0 | 0.033 | 0.0 | 0.967 |
| 07 | 0.96 | 0.001 | 0.007 | 0.033 |
| 08 | 0.381 | 0.187 | 0.263 | 0.169 |
| 09 | 0.13 | 0.343 | 0.323 | 0.205 |
| 10 | 0.218 | 0.254 | 0.263 | 0.265 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.056 | 0.142 | 0.089 | -0.362 |
| 02 | -0.071 | -0.599 | 0.712 | -0.733 |
| 03 | -2.293 | -2.846 | 1.343 | -4.476 |
| 04 | 0.969 | 0.308 | -6.953 | -6.326 |
| 05 | -6.953 | -6.953 | -6.953 | 1.386 |
| 06 | -6.953 | -2.029 | -6.953 | 1.352 |
| 07 | 1.344 | -5.796 | -3.488 | -2.033 |
| 08 | 0.42 | -0.29 | 0.05 | -0.389 |
| 09 | -0.656 | 0.315 | 0.256 | -0.2 |
| 10 | -0.138 | 0.018 | 0.051 | 0.057 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.697405 |
| 0.0005 | 6.321965 |
| 0.0001 | 7.203185 |