Motif | OTX1.H12CORE.1.S.B |
Gene (human) | OTX1 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Otx1 |
Gene synonyms (mouse) | Otx-1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | OTX1.H12CORE.1.S.B |
Gene (human) | OTX1 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Otx1 |
Gene synonyms (mouse) | Otx-1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 14 |
Consensus | WWAKCGGATTAdnn |
GC content | 37.88% |
Information content (bits; total / per base) | 15.757 / 1.126 |
Data sources | HT-SELEX |
Aligned words | 1661 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 10 experiments | median | 0.931 | 0.887 | 0.912 | 0.864 | 0.846 | 0.811 |
best | 0.992 | 0.989 | 0.975 | 0.962 | 0.951 | 0.932 | |
Methyl HT-SELEX, 3 experiments | median | 0.925 | 0.877 | 0.907 | 0.855 | 0.86 | 0.812 |
best | 0.985 | 0.977 | 0.972 | 0.958 | 0.934 | 0.916 | |
Non-Methyl HT-SELEX, 7 experiments | median | 0.936 | 0.897 | 0.917 | 0.872 | 0.832 | 0.81 |
best | 0.992 | 0.989 | 0.975 | 0.962 | 0.951 | 0.932 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.982 | 0.808 | 0.957 | 0.525 |
batch 2 | 0.822 | 0.652 | 0.866 | 0.655 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | OTX {3.1.3.17} (TFClass) |
TFClass ID | TFClass: 3.1.3.17.1 |
HGNC | HGNC:8521 |
MGI | MGI:97450 |
EntrezGene (human) | GeneID:5013 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18423 (SSTAR profile) |
UniProt ID (human) | OTX1_HUMAN |
UniProt ID (mouse) | OTX1_MOUSE |
UniProt AC (human) | P32242 (TFClass) |
UniProt AC (mouse) | P80205 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 7 |
Methyl-HT-SELEX | 3 |
PCM | OTX1.H12CORE.1.S.B.pcm |
PWM | OTX1.H12CORE.1.S.B.pwm |
PFM | OTX1.H12CORE.1.S.B.pfm |
Alignment | OTX1.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | OTX1.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | OTX1.H12CORE.1.S.B_jaspar_format.txt |
MEME format | OTX1.H12CORE.1.S.B_meme_format.meme |
Transfac format | OTX1.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 321.25 | 159.25 | 131.25 | 1049.25 |
02 | 1232.5 | 151.5 | 114.5 | 162.5 |
03 | 1368.0 | 67.0 | 93.0 | 133.0 |
04 | 68.0 | 176.0 | 631.0 | 786.0 |
05 | 48.0 | 1548.0 | 36.0 | 29.0 |
06 | 16.0 | 258.0 | 1379.0 | 8.0 |
07 | 0.0 | 0.0 | 1661.0 | 0.0 |
08 | 1607.0 | 54.0 | 0.0 | 0.0 |
09 | 0.0 | 0.0 | 0.0 | 1661.0 |
10 | 0.0 | 0.0 | 0.0 | 1661.0 |
11 | 1660.0 | 0.0 | 0.0 | 1.0 |
12 | 920.0 | 175.0 | 348.0 | 218.0 |
13 | 230.5 | 357.5 | 568.5 | 504.5 |
14 | 353.5 | 458.5 | 440.5 | 408.5 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.193 | 0.096 | 0.079 | 0.632 |
02 | 0.742 | 0.091 | 0.069 | 0.098 |
03 | 0.824 | 0.04 | 0.056 | 0.08 |
04 | 0.041 | 0.106 | 0.38 | 0.473 |
05 | 0.029 | 0.932 | 0.022 | 0.017 |
06 | 0.01 | 0.155 | 0.83 | 0.005 |
07 | 0.0 | 0.0 | 1.0 | 0.0 |
08 | 0.967 | 0.033 | 0.0 | 0.0 |
09 | 0.0 | 0.0 | 0.0 | 1.0 |
10 | 0.0 | 0.0 | 0.0 | 1.0 |
11 | 0.999 | 0.0 | 0.0 | 0.001 |
12 | 0.554 | 0.105 | 0.21 | 0.131 |
13 | 0.139 | 0.215 | 0.342 | 0.304 |
14 | 0.213 | 0.276 | 0.265 | 0.246 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.255 | -0.951 | -1.142 | 0.924 |
02 | 1.085 | -1.001 | -1.277 | -0.931 |
03 | 1.189 | -1.801 | -1.481 | -1.129 |
04 | -1.787 | -0.852 | 0.417 | 0.636 |
05 | -2.124 | 1.313 | -2.4 | -2.604 |
06 | -3.151 | -0.473 | 1.197 | -3.745 |
07 | -5.416 | -5.416 | 1.383 | -5.416 |
08 | 1.35 | -2.011 | -5.416 | -5.416 |
09 | -5.416 | -5.416 | -5.416 | 1.383 |
10 | -5.416 | -5.416 | -5.416 | 1.383 |
11 | 1.382 | -5.416 | -5.416 | -4.985 |
12 | 0.793 | -0.858 | -0.176 | -0.64 |
13 | -0.585 | -0.149 | 0.313 | 0.194 |
14 | -0.16 | 0.099 | 0.059 | -0.016 |
P-value | Threshold |
---|---|
0.001 | 1.54041 |
0.0005 | 3.05361 |
0.0001 | 6.18371 |