MotifOTX1.H12CORE.1.S.B
Gene (human)OTX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Otx1
Gene synonyms (mouse)Otx-1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusWWAKCGGATTAdnn
GC content37.88%
Information content (bits; total / per base)15.757 / 1.126
Data sourcesHT-SELEX
Aligned words1661

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.931 0.887 0.912 0.864 0.846 0.811
best 0.992 0.989 0.975 0.962 0.951 0.932
Methyl HT-SELEX, 3 experiments median 0.925 0.877 0.907 0.855 0.86 0.812
best 0.985 0.977 0.972 0.958 0.934 0.916
Non-Methyl HT-SELEX, 7 experiments median 0.936 0.897 0.917 0.872 0.832 0.81
best 0.992 0.989 0.975 0.962 0.951 0.932

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.982 0.808 0.957 0.525
batch 2 0.822 0.652 0.866 0.655
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyOTX {3.1.3.17} (TFClass)
TFClass IDTFClass: 3.1.3.17.1
HGNCHGNC:8521
MGIMGI:97450
EntrezGene (human)GeneID:5013
(SSTAR profile)
EntrezGene (mouse)GeneID:18423
(SSTAR profile)
UniProt ID (human)OTX1_HUMAN
UniProt ID (mouse)OTX1_MOUSE
UniProt AC (human)P32242
(TFClass)
UniProt AC (mouse)P80205
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
01321.25159.25131.251049.25
021232.5151.5114.5162.5
031368.067.093.0133.0
0468.0176.0631.0786.0
0548.01548.036.029.0
0616.0258.01379.08.0
070.00.01661.00.0
081607.054.00.00.0
090.00.00.01661.0
100.00.00.01661.0
111660.00.00.01.0
12920.0175.0348.0218.0
13230.5357.5568.5504.5
14353.5458.5440.5408.5
PFM
ACGT
010.1930.0960.0790.632
020.7420.0910.0690.098
030.8240.040.0560.08
040.0410.1060.380.473
050.0290.9320.0220.017
060.010.1550.830.005
070.00.01.00.0
080.9670.0330.00.0
090.00.00.01.0
100.00.00.01.0
110.9990.00.00.001
120.5540.1050.210.131
130.1390.2150.3420.304
140.2130.2760.2650.246
PWM
ACGT
01-0.255-0.951-1.1420.924
021.085-1.001-1.277-0.931
031.189-1.801-1.481-1.129
04-1.787-0.8520.4170.636
05-2.1241.313-2.4-2.604
06-3.151-0.4731.197-3.745
07-5.416-5.4161.383-5.416
081.35-2.011-5.416-5.416
09-5.416-5.416-5.4161.383
10-5.416-5.416-5.4161.383
111.382-5.416-5.416-4.985
120.793-0.858-0.176-0.64
13-0.585-0.1490.3130.194
14-0.160.0990.059-0.016
Standard thresholds
P-value Threshold
0.001 1.54041
0.0005 3.05361
0.0001 6.18371