OSR2.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	OSR2.H12INVITRO.0.PSM.A
Gene (human)	OSR2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Osr2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	10
Consensus	nhGCTACYdb
GC content	56.96%
Information content (bits; total / per base)	10.087 / 1.009
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	8185

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.706	0.79	0.564	0.651	0.668	0.741	1.711	2.042	59.178	182.569

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.882	0.859	0.752	0.739	0.652	0.655
Overall, 2 experiments	best	0.918	0.896	0.792	0.776	0.678	0.681
Methyl HT-SELEX, 1 experiments	median	0.846	0.823	0.712	0.703	0.627	0.63
Methyl HT-SELEX, 1 experiments	best	0.846	0.823	0.712	0.703	0.627	0.63
Non-Methyl HT-SELEX, 1 experiments	median	0.918	0.896	0.792	0.776	0.678	0.681
Non-Methyl HT-SELEX, 1 experiments	best	0.918	0.896	0.792	0.776	0.678	0.681

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	13.93	2.979	0.174	0.102

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.9
HGNC	HGNC:15830
MGI	MGI:1930813
EntrezGene (human)	GeneID:116039 (SSTAR profile)
EntrezGene (mouse)	GeneID:107587 (SSTAR profile)
UniProt ID (human)	OSR2_HUMAN
UniProt ID (mouse)	OSR2_MOUSE
UniProt AC (human)	Q8N2R0 (TFClass)
UniProt AC (mouse)	Q91ZD1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	OSR2.H12INVITRO.0.PSM.A.pcm
PWM	OSR2.H12INVITRO.0.PSM.A.pwm
PFM	OSR2.H12INVITRO.0.PSM.A.pfm
Alignment	OSR2.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	OSR2.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	OSR2.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	OSR2.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	OSR2.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	OSR2.H12INVITRO.0.PSM.A_homer_format_0.001.txt OSR2.H12INVITRO.0.PSM.A_homer_format_0.0005.txt OSR2.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1699.0	2355.0	1834.0	2297.0
02	2172.0	2086.0	950.0	2977.0
03	203.0	789.0	7179.0	14.0
04	13.0	8170.0	1.0	1.0
05	0.0	436.0	0.0	7749.0
06	7608.0	133.0	1.0	443.0
07	5.0	8180.0	0.0	0.0
08	50.0	4721.0	120.0	3294.0
09	1046.0	1009.0	4911.0	1219.0
10	1297.0	2261.0	1482.0	3145.0

PFM

	A	C	G	T
01	0.208	0.288	0.224	0.281
02	0.265	0.255	0.116	0.364
03	0.025	0.096	0.877	0.002
04	0.002	0.998	0.0	0.0
05	0.0	0.053	0.0	0.947
06	0.93	0.016	0.0	0.054
07	0.001	0.999	0.0	0.0
08	0.006	0.577	0.015	0.402
09	0.128	0.123	0.6	0.149
10	0.158	0.276	0.181	0.384

PWM

	A	C	G	T
01	-0.186	0.14	-0.109	0.115
02	0.06	0.019	-0.766	0.375
03	-2.301	-0.951	1.254	-4.837
04	-4.9	1.384	-6.445	-6.445
05	-6.813	-1.542	-6.813	1.331
06	1.312	-2.718	-6.445	-1.526
07	-5.644	1.385	-6.813	-6.813
08	-3.669	0.835	-2.819	0.476
09	-0.67	-0.706	0.875	-0.517
10	-0.455	0.1	-0.322	0.429

Standard thresholds

P-value	Threshold
0.001	4.730635
0.0005	5.964815
0.0001	7.611315