ONEC3.H12RSNP.1.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ONEC3.H12RSNP.1.S.D
Gene (human)	ONECUT3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Onecut3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	11
Consensus	nbATCGATTdn
GC content	40.31%
Information content (bits; total / per base)	13.536 / 1.231
Data sources	HT-SELEX
Aligned words	7023

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.972	0.951	0.904	0.894	0.814	0.829
Overall, 4 experiments	best	0.99	0.981	0.987	0.977	0.981	0.96
Methyl HT-SELEX, 1 experiments	median	0.97	0.95	0.977	0.954	0.981	0.96
Methyl HT-SELEX, 1 experiments	best	0.97	0.95	0.977	0.954	0.981	0.96
Non-Methyl HT-SELEX, 3 experiments	median	0.974	0.952	0.831	0.833	0.657	0.697
Non-Methyl HT-SELEX, 3 experiments	best	0.99	0.981	0.987	0.977	0.972	0.96

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HD-CUT {3.1.9} (TFClass)
TF subfamily	ONECUT {3.1.9.1} (TFClass)
TFClass ID	TFClass: 3.1.9.1.3
HGNC	HGNC:13399
MGI	MGI:1891409
EntrezGene (human)	GeneID:390874 (SSTAR profile)
EntrezGene (mouse)	GeneID:246086 (SSTAR profile)
UniProt ID (human)	ONEC3_HUMAN
UniProt ID (mouse)	ONEC3_MOUSE
UniProt AC (human)	O60422 (TFClass)
UniProt AC (mouse)	Q8K557 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	ONEC3.H12RSNP.1.S.D.pcm
PWM	ONEC3.H12RSNP.1.S.D.pwm
PFM	ONEC3.H12RSNP.1.S.D.pfm
Alignment	ONEC3.H12RSNP.1.S.D.words.tsv
Threshold to P-value map	ONEC3.H12RSNP.1.S.D.thr
Motif in other formats
JASPAR format	ONEC3.H12RSNP.1.S.D_jaspar_format.txt
MEME format	ONEC3.H12RSNP.1.S.D_meme_format.meme
Transfac format	ONEC3.H12RSNP.1.S.D_transfac_format.txt
Homer format	ONEC3.H12RSNP.1.S.D_homer_format_0.001.txt ONEC3.H12RSNP.1.S.D_homer_format_0.0005.txt ONEC3.H12RSNP.1.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1110.25	1586.25	2553.25	1773.25
02	750.0	766.0	1960.0	3547.0
03	7023.0	0.0	0.0	0.0
04	0.0	0.0	0.0	7023.0
05	0.0	6686.0	0.0	337.0
06	0.0	0.0	7023.0	0.0
07	7023.0	0.0	0.0	0.0
08	0.0	0.0	0.0	7023.0
09	0.0	2480.0	0.0	4543.0
10	1716.5	604.5	3818.5	883.5
11	2283.25	1731.25	1934.25	1074.25

PFM

	A	C	G	T
01	0.158	0.226	0.364	0.252
02	0.107	0.109	0.279	0.505
03	1.0	0.0	0.0	0.0
04	0.0	0.0	0.0	1.0
05	0.0	0.952	0.0	0.048
06	0.0	0.0	1.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.353	0.0	0.647
10	0.244	0.086	0.544	0.126
11	0.325	0.247	0.275	0.153

PWM

	A	C	G	T
01	-0.458	-0.101	0.374	0.01
02	-0.849	-0.828	0.11	0.703
03	1.385	-6.677	-6.677	-6.677
04	-6.677	-6.677	-6.677	1.385
05	-6.677	1.336	-6.677	-1.645
06	-6.677	-6.677	1.385	-6.677
07	1.385	-6.677	-6.677	-6.677
08	-6.677	-6.677	-6.677	1.385
09	-6.677	0.345	-6.677	0.95
10	-0.023	-1.064	0.776	-0.686
11	0.262	-0.014	0.097	-0.49

Standard thresholds

P-value	Threshold
0.001	0.7845
0.0005	1.71196
0.0001	7.43589