ONEC3.H12RSNP.0.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ONEC3.H12RSNP.0.S.D
Gene (human)	ONECUT3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Onecut3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	14
Consensus	nbTATTGATTWdbn
GC content	25.52%
Information content (bits; total / per base)	14.906 / 1.065
Data sources	HT-SELEX
Aligned words	8841

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.986	0.974	0.897	0.899	0.796	0.816
Overall, 4 experiments	best	0.993	0.99	0.99	0.981	0.987	0.977
Methyl HT-SELEX, 1 experiments	median	0.991	0.983	0.99	0.981	0.987	0.977
Methyl HT-SELEX, 1 experiments	best	0.991	0.983	0.99	0.981	0.987	0.977
Non-Methyl HT-SELEX, 3 experiments	median	0.981	0.965	0.815	0.838	0.629	0.689
Non-Methyl HT-SELEX, 3 experiments	best	0.993	0.99	0.979	0.961	0.962	0.943

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HD-CUT {3.1.9} (TFClass)
TF subfamily	ONECUT {3.1.9.1} (TFClass)
TFClass ID	TFClass: 3.1.9.1.3
HGNC	HGNC:13399
MGI	MGI:1891409
EntrezGene (human)	GeneID:390874 (SSTAR profile)
EntrezGene (mouse)	GeneID:246086 (SSTAR profile)
UniProt ID (human)	ONEC3_HUMAN
UniProt ID (mouse)	ONEC3_MOUSE
UniProt AC (human)	O60422 (TFClass)
UniProt AC (mouse)	Q8K557 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	ONEC3.H12RSNP.0.S.D.pcm
PWM	ONEC3.H12RSNP.0.S.D.pwm
PFM	ONEC3.H12RSNP.0.S.D.pfm
Alignment	ONEC3.H12RSNP.0.S.D.words.tsv
Threshold to P-value map	ONEC3.H12RSNP.0.S.D.thr
Motif in other formats
JASPAR format	ONEC3.H12RSNP.0.S.D_jaspar_format.txt
MEME format	ONEC3.H12RSNP.0.S.D_meme_format.meme
Transfac format	ONEC3.H12RSNP.0.S.D_transfac_format.txt
Homer format	ONEC3.H12RSNP.0.S.D_homer_format_0.001.txt ONEC3.H12RSNP.0.S.D_homer_format_0.0005.txt ONEC3.H12RSNP.0.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2441.0	1678.0	1795.0	2927.0
02	1327.25	1380.25	1606.25	4527.25
03	781.0	413.0	424.0	7223.0
04	8742.0	35.0	29.0	35.0
05	6.0	38.0	5.0	8792.0
06	0.0	4145.0	0.0	4696.0
07	1.0	0.0	8840.0	0.0
08	8834.0	0.0	5.0	2.0
09	1.0	29.0	19.0	8792.0
10	91.0	250.0	39.0	8461.0
11	2243.0	190.0	887.0	5521.0
12	1701.0	1018.0	1402.0	4720.0
13	1297.75	1849.75	1453.75	4239.75
14	1595.0	1852.0	2199.0	3195.0

PFM

	A	C	G	T
01	0.276	0.19	0.203	0.331
02	0.15	0.156	0.182	0.512
03	0.088	0.047	0.048	0.817
04	0.989	0.004	0.003	0.004
05	0.001	0.004	0.001	0.994
06	0.0	0.469	0.0	0.531
07	0.0	0.0	1.0	0.0
08	0.999	0.0	0.001	0.0
09	0.0	0.003	0.002	0.994
10	0.01	0.028	0.004	0.957
11	0.254	0.021	0.1	0.624
12	0.192	0.115	0.159	0.534
13	0.147	0.209	0.164	0.48
14	0.18	0.209	0.249	0.361

PWM

	A	C	G	T
01	0.099	-0.275	-0.208	0.281
02	-0.509	-0.47	-0.319	0.716
03	-1.038	-1.673	-1.647	1.183
04	1.374	-4.084	-4.259	-4.084
05	-5.589	-4.006	-5.718	1.38
06	-6.881	0.628	-6.881	0.753
07	-6.517	-6.881	1.385	-6.881
08	1.385	-6.881	-5.718	-6.25
09	-6.517	-4.259	-4.645	1.38
10	-3.166	-2.171	-3.982	1.342
11	0.015	-2.443	-0.911	0.915
12	-0.262	-0.774	-0.455	0.758
13	-0.532	-0.178	-0.418	0.651
14	-0.326	-0.177	-0.005	0.368

Standard thresholds

P-value	Threshold
0.001	1.37716
0.0005	2.91476
0.0001	6.279075