ONEC3.H12CORE.2.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ONEC3.H12CORE.2.M.C
Gene (human)	ONECUT3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Onecut3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	C

Motif length	13
Consensus	nbTATTGATTRdb
GC content	27.86%
Information content (bits; total / per base)	15.839 / 1.218
Data sources	Methyl-HT-SELEX
Aligned words	782

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.966	0.951	0.886	0.873	0.786	0.79
Overall, 4 experiments	best	0.996	0.991	0.995	0.99	0.991	0.985
Methyl HT-SELEX, 1 experiments	median	0.996	0.991	0.995	0.99	0.991	0.985
Methyl HT-SELEX, 1 experiments	best	0.996	0.991	0.995	0.99	0.991	0.985
Non-Methyl HT-SELEX, 3 experiments	median	0.956	0.944	0.816	0.813	0.65	0.685
Non-Methyl HT-SELEX, 3 experiments	best	0.976	0.958	0.956	0.934	0.923	0.894

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HD-CUT {3.1.9} (TFClass)
TF subfamily	ONECUT {3.1.9.1} (TFClass)
TFClass ID	TFClass: 3.1.9.1.3
HGNC	HGNC:13399
MGI	MGI:1891409
EntrezGene (human)	GeneID:390874 (SSTAR profile)
EntrezGene (mouse)	GeneID:246086 (SSTAR profile)
UniProt ID (human)	ONEC3_HUMAN
UniProt ID (mouse)	ONEC3_MOUSE
UniProt AC (human)	O60422 (TFClass)
UniProt AC (mouse)	Q8K557 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	ONEC3.H12CORE.2.M.C.pcm
PWM	ONEC3.H12CORE.2.M.C.pwm
PFM	ONEC3.H12CORE.2.M.C.pfm
Alignment	ONEC3.H12CORE.2.M.C.words.tsv
Threshold to P-value map	ONEC3.H12CORE.2.M.C.thr
Motif in other formats
JASPAR format	ONEC3.H12CORE.2.M.C_jaspar_format.txt
MEME format	ONEC3.H12CORE.2.M.C_meme_format.meme
Transfac format	ONEC3.H12CORE.2.M.C_transfac_format.txt
Homer format	ONEC3.H12CORE.2.M.C_homer_format_0.001.txt ONEC3.H12CORE.2.M.C_homer_format_0.0005.txt ONEC3.H12CORE.2.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	241.25	162.25	233.25	145.25
02	106.25	158.25	270.25	247.25
03	24.0	19.0	31.0	708.0
04	782.0	0.0	0.0	0.0
05	0.0	0.0	0.0	782.0
06	0.0	0.0	0.0	782.0
07	0.0	0.0	782.0	0.0
08	781.0	1.0	0.0	0.0
09	0.0	1.0	0.0	781.0
10	0.0	162.0	0.0	620.0
11	186.0	25.0	468.0	103.0
12	446.5	94.5	124.5	116.5
13	96.75	182.75	117.75	384.75

PFM

	A	C	G	T
01	0.309	0.207	0.298	0.186
02	0.136	0.202	0.346	0.316
03	0.031	0.024	0.04	0.905
04	1.0	0.0	0.0	0.0
05	0.0	0.0	0.0	1.0
06	0.0	0.0	0.0	1.0
07	0.0	0.0	1.0	0.0
08	0.999	0.001	0.0	0.0
09	0.0	0.001	0.0	0.999
10	0.0	0.207	0.0	0.793
11	0.238	0.032	0.598	0.132
12	0.571	0.121	0.159	0.149
13	0.124	0.234	0.151	0.492

PWM

	A	C	G	T
01	0.209	-0.185	0.175	-0.294
02	-0.603	-0.209	0.321	0.233
03	-2.039	-2.256	-1.798	1.281
04	1.38	-4.774	-4.774	-4.774
05	-4.774	-4.774	-4.774	1.38
06	-4.774	-4.774	-4.774	1.38
07	-4.774	-4.774	1.38	-4.774
08	1.379	-4.304	-4.774	-4.774
09	-4.774	-4.304	-4.774	1.379
10	-4.774	-0.186	-4.774	1.148
11	-0.049	-2.001	0.868	-0.633
12	0.821	-0.718	-0.446	-0.512
13	-0.695	-0.067	-0.501	0.673

Standard thresholds

P-value	Threshold
0.001	1.13901
0.0005	2.758875
0.0001	5.78334