MotifONEC2.H12INVIVO.3.P.B
Gene (human)ONECUT2
(GeneCards)
Gene synonyms (human)HNF6B
Gene (mouse)Onecut2
Gene synonyms (mouse)Oc2
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
B
Motif length22
ConsensusKKATTGATTKWTTKWhTKRKWK
GC content25.97%
Information content (bits; total / per base)25.543 / 1.161
Data sourcesChIP-Seq
Aligned words324

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (22) 0.741 0.882 0.603 0.772 0.72 0.797 2.523 3.094 24.561 95.959
Mouse 2 (12) 0.893 0.924 0.844 0.889 0.787 0.835 5.381 6.746 279.353 350.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.962 0.945 0.87 0.856 0.79 0.764
best 0.994 0.989 0.99 0.984 0.976 0.967
Methyl HT-SELEX, 3 experiments median 0.994 0.989 0.984 0.977 0.91 0.904
best 0.994 0.989 0.99 0.984 0.976 0.967
Non-Methyl HT-SELEX, 5 experiments median 0.86 0.811 0.787 0.741 0.704 0.677
best 0.97 0.952 0.947 0.921 0.918 0.885
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyONECUT {3.1.9.1} (TFClass)
TFClass IDTFClass: 3.1.9.1.2
HGNCHGNC:8139
MGIMGI:1891408
EntrezGene (human)GeneID:9480
(SSTAR profile)
EntrezGene (mouse)GeneID:225631
(SSTAR profile)
UniProt ID (human)ONEC2_HUMAN
UniProt ID (mouse)ONEC2_MOUSE
UniProt AC (human)O95948
(TFClass)
UniProt AC (mouse)Q6XBJ3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 2 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
0129.033.040.0222.0
023.018.0103.0200.0
03324.00.00.00.0
040.00.00.0324.0
051.00.00.0323.0
060.00.0323.01.0
07324.00.00.00.0
080.03.00.0321.0
090.012.00.0312.0
1023.013.0170.0118.0
11217.023.027.057.0
1215.019.08.0282.0
1312.016.09.0287.0
1415.017.0234.058.0
15242.020.027.035.0
1623.023.020.0258.0
1713.012.025.0274.0
1829.017.0219.059.0
19221.029.042.032.0
2023.029.035.0237.0
2134.029.023.0238.0
2233.032.0201.058.0
PFM
ACGT
010.090.1020.1230.685
020.0090.0560.3180.617
031.00.00.00.0
040.00.00.01.0
050.0030.00.00.997
060.00.00.9970.003
071.00.00.00.0
080.00.0090.00.991
090.00.0370.00.963
100.0710.040.5250.364
110.670.0710.0830.176
120.0460.0590.0250.87
130.0370.0490.0280.886
140.0460.0520.7220.179
150.7470.0620.0830.108
160.0710.0710.0620.796
170.040.0370.0770.846
180.090.0520.6760.182
190.6820.090.130.099
200.0710.090.1080.731
210.1050.090.0710.735
220.1020.0990.620.179
PWM
ACGT
01-0.996-0.873-0.6880.997
02-2.92-1.4450.2370.893
031.373-4.044-4.044-4.044
04-4.044-4.044-4.0441.373
05-3.518-4.044-4.0441.37
06-4.044-4.0441.37-3.518
071.373-4.044-4.044-4.044
08-4.044-2.92-4.0441.364
09-4.044-1.814-4.0441.335
10-1.216-1.7420.7320.371
110.974-1.216-1.064-0.344
12-1.612-1.394-2.1671.235
13-1.814-1.553-2.0661.252
14-1.612-1.4971.049-0.327
151.083-1.347-1.064-0.816
16-1.216-1.216-1.3471.146
17-1.742-1.814-1.1371.206
18-0.996-1.4970.984-0.31
190.993-0.996-0.641-0.902
20-1.216-0.996-0.8161.062
21-0.844-0.996-1.2161.066
22-0.873-0.9020.898-0.327
Standard thresholds
P-value Threshold
0.001 -2.25924
0.0005 -0.66299
0.0001 2.73986