| Motif | ONEC2.H12INVITRO.3.P.B |
| Gene (human) | ONECUT2 (GeneCards) |
| Gene synonyms (human) | HNF6B |
| Gene (mouse) | Onecut2 |
| Gene synonyms (mouse) | Oc2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 3 |
| Quality | B |
| Motif | ONEC2.H12INVITRO.3.P.B |
| Gene (human) | ONECUT2 (GeneCards) |
| Gene synonyms (human) | HNF6B |
| Gene (mouse) | Onecut2 |
| Gene synonyms (mouse) | Oc2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 3 |
| Quality | B |
| Motif length | 22 |
| Consensus | ATKKWTTKATTGATTKWTTKWT |
| GC content | 22.34% |
| Information content (bits; total / per base) | 28.307 / 1.287 |
| Data sources | ChIP-Seq |
| Aligned words | 257 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 4 (22) | 0.762 | 0.89 | 0.676 | 0.846 | 0.684 | 0.769 | 2.388 | 2.9 | 20.194 | 62.921 |
| Mouse | 2 (12) | 0.962 | 0.978 | 0.934 | 0.959 | 0.742 | 0.793 | 5.064 | 6.505 | 245.37 | 325.959 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.967 | 0.95 | 0.885 | 0.867 | 0.783 | 0.765 |
| best | 0.994 | 0.991 | 0.99 | 0.984 | 0.981 | 0.972 | |
| Methyl HT-SELEX, 3 experiments | median | 0.993 | 0.988 | 0.99 | 0.983 | 0.967 | 0.958 |
| best | 0.994 | 0.991 | 0.99 | 0.984 | 0.981 | 0.972 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.905 | 0.858 | 0.839 | 0.794 | 0.729 | 0.711 |
| best | 0.983 | 0.969 | 0.977 | 0.96 | 0.963 | 0.943 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HD-CUT {3.1.9} (TFClass) |
| TF subfamily | ONECUT {3.1.9.1} (TFClass) |
| TFClass ID | TFClass: 3.1.9.1.2 |
| HGNC | HGNC:8139 |
| MGI | MGI:1891408 |
| EntrezGene (human) | GeneID:9480 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:225631 (SSTAR profile) |
| UniProt ID (human) | ONEC2_HUMAN |
| UniProt ID (mouse) | ONEC2_MOUSE |
| UniProt AC (human) | O95948 (TFClass) |
| UniProt AC (mouse) | Q6XBJ3 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 4 human, 2 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 3 |
| PCM | ONEC2.H12INVITRO.3.P.B.pcm |
| PWM | ONEC2.H12INVITRO.3.P.B.pwm |
| PFM | ONEC2.H12INVITRO.3.P.B.pfm |
| Alignment | ONEC2.H12INVITRO.3.P.B.words.tsv |
| Threshold to P-value map | ONEC2.H12INVITRO.3.P.B.thr |
| Motif in other formats | |
| JASPAR format | ONEC2.H12INVITRO.3.P.B_jaspar_format.txt |
| MEME format | ONEC2.H12INVITRO.3.P.B_meme_format.meme |
| Transfac format | ONEC2.H12INVITRO.3.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 203.0 | 7.0 | 7.0 | 40.0 |
| 02 | 22.0 | 11.0 | 9.0 | 215.0 |
| 03 | 19.0 | 12.0 | 20.0 | 206.0 |
| 04 | 21.0 | 14.0 | 191.0 | 31.0 |
| 05 | 191.0 | 24.0 | 10.0 | 32.0 |
| 06 | 13.0 | 15.0 | 7.0 | 222.0 |
| 07 | 7.0 | 8.0 | 13.0 | 229.0 |
| 08 | 4.0 | 10.0 | 127.0 | 116.0 |
| 09 | 257.0 | 0.0 | 0.0 | 0.0 |
| 10 | 0.0 | 0.0 | 0.0 | 257.0 |
| 11 | 0.0 | 1.0 | 0.0 | 256.0 |
| 12 | 0.0 | 0.0 | 257.0 | 0.0 |
| 13 | 257.0 | 0.0 | 0.0 | 0.0 |
| 14 | 0.0 | 0.0 | 0.0 | 257.0 |
| 15 | 0.0 | 4.0 | 0.0 | 253.0 |
| 16 | 11.0 | 7.0 | 154.0 | 85.0 |
| 17 | 179.0 | 13.0 | 20.0 | 45.0 |
| 18 | 6.0 | 20.0 | 4.0 | 227.0 |
| 19 | 6.0 | 7.0 | 13.0 | 231.0 |
| 20 | 12.0 | 16.0 | 185.0 | 44.0 |
| 21 | 176.0 | 23.0 | 17.0 | 41.0 |
| 22 | 13.0 | 22.0 | 15.0 | 207.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.79 | 0.027 | 0.027 | 0.156 |
| 02 | 0.086 | 0.043 | 0.035 | 0.837 |
| 03 | 0.074 | 0.047 | 0.078 | 0.802 |
| 04 | 0.082 | 0.054 | 0.743 | 0.121 |
| 05 | 0.743 | 0.093 | 0.039 | 0.125 |
| 06 | 0.051 | 0.058 | 0.027 | 0.864 |
| 07 | 0.027 | 0.031 | 0.051 | 0.891 |
| 08 | 0.016 | 0.039 | 0.494 | 0.451 |
| 09 | 1.0 | 0.0 | 0.0 | 0.0 |
| 10 | 0.0 | 0.0 | 0.0 | 1.0 |
| 11 | 0.0 | 0.004 | 0.0 | 0.996 |
| 12 | 0.0 | 0.0 | 1.0 | 0.0 |
| 13 | 1.0 | 0.0 | 0.0 | 0.0 |
| 14 | 0.0 | 0.0 | 0.0 | 1.0 |
| 15 | 0.0 | 0.016 | 0.0 | 0.984 |
| 16 | 0.043 | 0.027 | 0.599 | 0.331 |
| 17 | 0.696 | 0.051 | 0.078 | 0.175 |
| 18 | 0.023 | 0.078 | 0.016 | 0.883 |
| 19 | 0.023 | 0.027 | 0.051 | 0.899 |
| 20 | 0.047 | 0.062 | 0.72 | 0.171 |
| 21 | 0.685 | 0.089 | 0.066 | 0.16 |
| 22 | 0.051 | 0.086 | 0.058 | 0.805 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1.136 | -2.057 | -2.057 | -0.461 |
| 02 | -1.032 | -1.667 | -1.844 | 1.193 |
| 03 | -1.169 | -1.59 | -1.121 | 1.15 |
| 04 | -1.076 | -1.451 | 1.075 | -0.706 |
| 05 | 1.075 | -0.95 | -1.752 | -0.676 |
| 06 | -1.518 | -1.388 | -2.057 | 1.225 |
| 07 | -2.057 | -1.945 | -1.518 | 1.256 |
| 08 | -2.5 | -1.752 | 0.671 | 0.581 |
| 09 | 1.37 | -3.857 | -3.857 | -3.857 |
| 10 | -3.857 | -3.857 | -3.857 | 1.37 |
| 11 | -3.857 | -3.314 | -3.857 | 1.366 |
| 12 | -3.857 | -3.857 | 1.37 | -3.857 |
| 13 | 1.37 | -3.857 | -3.857 | -3.857 |
| 14 | -3.857 | -3.857 | -3.857 | 1.37 |
| 15 | -3.857 | -2.5 | -3.857 | 1.355 |
| 16 | -1.667 | -2.057 | 0.862 | 0.275 |
| 17 | 1.011 | -1.518 | -1.121 | -0.347 |
| 18 | -2.184 | -1.121 | -2.5 | 1.247 |
| 19 | -2.184 | -2.057 | -1.518 | 1.264 |
| 20 | -1.59 | -1.328 | 1.044 | -0.369 |
| 21 | 0.994 | -0.99 | -1.272 | -0.437 |
| 22 | -1.518 | -1.032 | -1.388 | 1.155 |
| P-value | Threshold |
|---|---|
| 0.001 | -3.64719 |
| 0.0005 | -1.99139 |
| 0.0001 | 1.55491 |