MotifONEC2.H12INVITRO.1.PM.A
Gene (human)ONECUT2
(GeneCards)
Gene synonyms (human)HNF6B
Gene (mouse)Onecut2
Gene synonyms (mouse)Oc2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length13
ConsensusnbTATTGATYddb
GC content28.63%
Information content (bits; total / per base)15.55 / 1.196
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words2353

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (22) 0.811 0.931 0.704 0.894 0.798 0.863 2.746 3.215 51.255 220.013
Mouse 2 (12) 0.977 0.988 0.95 0.971 0.924 0.949 4.086 4.338 536.594 622.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.987 0.977 0.961 0.938 0.908 0.893
best 0.998 0.997 0.998 0.996 0.997 0.994
Methyl HT-SELEX, 3 experiments median 0.998 0.996 0.997 0.995 0.996 0.994
best 0.998 0.997 0.998 0.996 0.997 0.994
Non-Methyl HT-SELEX, 5 experiments median 0.96 0.932 0.937 0.905 0.831 0.815
best 0.993 0.988 0.992 0.986 0.992 0.985
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyONECUT {3.1.9.1} (TFClass)
TFClass IDTFClass: 3.1.9.1.2
HGNCHGNC:8139
MGIMGI:1891408
EntrezGene (human)GeneID:9480
(SSTAR profile)
EntrezGene (mouse)GeneID:225631
(SSTAR profile)
UniProt ID (human)ONEC2_HUMAN
UniProt ID (mouse)ONEC2_MOUSE
UniProt AC (human)O95948
(TFClass)
UniProt AC (mouse)Q6XBJ3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 2 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
01693.25488.25646.25525.25
02254.0262.0867.0970.0
0326.047.066.02214.0
042353.00.00.00.0
050.00.00.02353.0
060.031.00.02322.0
070.00.02353.00.0
082353.00.00.00.0
090.08.01.02344.0
105.0949.03.01396.0
11590.0143.01269.0351.0
121215.25256.25515.25366.25
13311.75456.75396.751187.75
PFM
ACGT
010.2950.2080.2750.223
020.1080.1110.3680.412
030.0110.020.0280.941
041.00.00.00.0
050.00.00.01.0
060.00.0130.00.987
070.00.01.00.0
081.00.00.00.0
090.00.0030.00.996
100.0020.4030.0010.593
110.2510.0610.5390.149
120.5160.1090.2190.156
130.1320.1940.1690.505
PWM
ACGT
010.164-0.1860.094-0.113
02-0.835-0.8050.3870.499
03-3.05-2.49-2.1621.323
041.384-5.717-5.717-5.717
05-5.717-5.717-5.7171.384
06-5.717-2.886-5.7171.371
07-5.717-5.7171.384-5.717
081.384-5.717-5.717-5.717
09-5.717-4.084-5.3021.38
10-4.4430.477-4.7830.862
110.003-1.4040.767-0.514
120.724-0.827-0.132-0.472
13-0.632-0.252-0.3920.701
Standard thresholds
P-value Threshold
0.001 0.38366
0.0005 2.31353
0.0001 5.559125