Motif | ONEC2.H12CORE.2.S.B |
Gene (human) | ONECUT2 (GeneCards) |
Gene synonyms (human) | HNF6B |
Gene (mouse) | Onecut2 |
Gene synonyms (mouse) | Oc2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif | ONEC2.H12CORE.2.S.B |
Gene (human) | ONECUT2 (GeneCards) |
Gene synonyms (human) | HNF6B |
Gene (mouse) | Onecut2 |
Gene synonyms (mouse) | Oc2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif length | 13 |
Consensus | nbTATCGATCGvb |
GC content | 43.97% |
Information content (bits; total / per base) | 16.095 / 1.238 |
Data sources | HT-SELEX |
Aligned words | 9457 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 4 (22) | 0.804 | 0.929 | 0.726 | 0.901 | 0.746 | 0.842 | 2.039 | 2.682 | 18.516 | 54.444 |
Mouse | 2 (12) | 0.981 | 0.99 | 0.951 | 0.971 | 0.911 | 0.917 | 3.09 | 3.234 | 359.208 | 405.155 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.99 | 0.982 | 0.98 | 0.97 | 0.928 | 0.922 |
best | 1.0 | 0.999 | 0.999 | 0.999 | 0.999 | 0.998 | |
Methyl HT-SELEX, 3 experiments | median | 0.993 | 0.989 | 0.991 | 0.984 | 0.99 | 0.982 |
best | 0.996 | 0.994 | 0.993 | 0.989 | 0.991 | 0.986 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.986 | 0.976 | 0.97 | 0.956 | 0.867 | 0.861 |
best | 1.0 | 0.999 | 0.999 | 0.999 | 0.999 | 0.998 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HD-CUT {3.1.9} (TFClass) |
TF subfamily | ONECUT {3.1.9.1} (TFClass) |
TFClass ID | TFClass: 3.1.9.1.2 |
HGNC | HGNC:8139 |
MGI | MGI:1891408 |
EntrezGene (human) | GeneID:9480 (SSTAR profile) |
EntrezGene (mouse) | GeneID:225631 (SSTAR profile) |
UniProt ID (human) | ONEC2_HUMAN |
UniProt ID (mouse) | ONEC2_MOUSE |
UniProt AC (human) | O95948 (TFClass) |
UniProt AC (mouse) | Q6XBJ3 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 4 human, 2 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 3 |
PCM | ONEC2.H12CORE.2.S.B.pcm |
PWM | ONEC2.H12CORE.2.S.B.pwm |
PFM | ONEC2.H12CORE.2.S.B.pfm |
Alignment | ONEC2.H12CORE.2.S.B.words.tsv |
Threshold to P-value map | ONEC2.H12CORE.2.S.B.thr |
Motif in other formats | |
JASPAR format | ONEC2.H12CORE.2.S.B_jaspar_format.txt |
MEME format | ONEC2.H12CORE.2.S.B_meme_format.meme |
Transfac format | ONEC2.H12CORE.2.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2268.5 | 2317.5 | 2856.5 | 2014.5 |
02 | 1133.25 | 1585.25 | 3033.25 | 3705.25 |
03 | 823.0 | 191.0 | 751.0 | 7692.0 |
04 | 9457.0 | 0.0 | 0.0 | 0.0 |
05 | 0.0 | 0.0 | 0.0 | 9457.0 |
06 | 0.0 | 9415.0 | 0.0 | 42.0 |
07 | 0.0 | 0.0 | 9457.0 | 0.0 |
08 | 9457.0 | 0.0 | 0.0 | 0.0 |
09 | 0.0 | 4.0 | 0.0 | 9453.0 |
10 | 10.0 | 8166.0 | 4.0 | 1277.0 |
11 | 481.0 | 612.0 | 7898.0 | 466.0 |
12 | 4267.0 | 1083.0 | 3106.0 | 1001.0 |
13 | 1374.5 | 1826.5 | 1753.5 | 4502.5 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.24 | 0.245 | 0.302 | 0.213 |
02 | 0.12 | 0.168 | 0.321 | 0.392 |
03 | 0.087 | 0.02 | 0.079 | 0.813 |
04 | 1.0 | 0.0 | 0.0 | 0.0 |
05 | 0.0 | 0.0 | 0.0 | 1.0 |
06 | 0.0 | 0.996 | 0.0 | 0.004 |
07 | 0.0 | 0.0 | 1.0 | 0.0 |
08 | 1.0 | 0.0 | 0.0 | 0.0 |
09 | 0.0 | 0.0 | 0.0 | 1.0 |
10 | 0.001 | 0.863 | 0.0 | 0.135 |
11 | 0.051 | 0.065 | 0.835 | 0.049 |
12 | 0.451 | 0.115 | 0.328 | 0.106 |
13 | 0.145 | 0.193 | 0.185 | 0.476 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.041 | -0.02 | 0.189 | -0.16 |
02 | -0.734 | -0.399 | 0.249 | 0.449 |
03 | -1.053 | -2.505 | -1.145 | 1.179 |
04 | 1.386 | -6.941 | -6.941 | -6.941 |
05 | -6.941 | -6.941 | -6.941 | 1.386 |
06 | -6.941 | 1.381 | -6.941 | -3.978 |
07 | -6.941 | -6.941 | 1.386 | -6.941 |
08 | 1.386 | -6.941 | -6.941 | -6.941 |
09 | -6.941 | -5.93 | -6.941 | 1.385 |
10 | -5.261 | 1.239 | -5.93 | -0.615 |
11 | -1.589 | -1.349 | 1.205 | -1.62 |
12 | 0.59 | -0.78 | 0.273 | -0.858 |
13 | -0.542 | -0.258 | -0.299 | 0.644 |
P-value | Threshold |
---|---|
0.001 | -0.85723 |
0.0005 | 0.86357 |
0.0001 | 5.00828 |