MotifONEC2.H12CORE.2.S.B
Gene (human)ONECUT2
(GeneCards)
Gene synonyms (human)HNF6B
Gene (mouse)Onecut2
Gene synonyms (mouse)Oc2
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length13
ConsensusnbTATCGATCGvb
GC content43.97%
Information content (bits; total / per base)16.095 / 1.238
Data sourcesHT-SELEX
Aligned words9457

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (22) 0.804 0.929 0.726 0.901 0.746 0.842 2.039 2.682 18.516 54.444
Mouse 2 (12) 0.981 0.99 0.951 0.971 0.911 0.917 3.09 3.234 359.208 405.155

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.99 0.982 0.98 0.97 0.928 0.922
best 1.0 0.999 0.999 0.999 0.999 0.998
Methyl HT-SELEX, 3 experiments median 0.993 0.989 0.991 0.984 0.99 0.982
best 0.996 0.994 0.993 0.989 0.991 0.986
Non-Methyl HT-SELEX, 5 experiments median 0.986 0.976 0.97 0.956 0.867 0.861
best 1.0 0.999 0.999 0.999 0.999 0.998
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyONECUT {3.1.9.1} (TFClass)
TFClass IDTFClass: 3.1.9.1.2
HGNCHGNC:8139
MGIMGI:1891408
EntrezGene (human)GeneID:9480
(SSTAR profile)
EntrezGene (mouse)GeneID:225631
(SSTAR profile)
UniProt ID (human)ONEC2_HUMAN
UniProt ID (mouse)ONEC2_MOUSE
UniProt AC (human)O95948
(TFClass)
UniProt AC (mouse)Q6XBJ3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 2 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
012268.52317.52856.52014.5
021133.251585.253033.253705.25
03823.0191.0751.07692.0
049457.00.00.00.0
050.00.00.09457.0
060.09415.00.042.0
070.00.09457.00.0
089457.00.00.00.0
090.04.00.09453.0
1010.08166.04.01277.0
11481.0612.07898.0466.0
124267.01083.03106.01001.0
131374.51826.51753.54502.5
PFM
ACGT
010.240.2450.3020.213
020.120.1680.3210.392
030.0870.020.0790.813
041.00.00.00.0
050.00.00.01.0
060.00.9960.00.004
070.00.01.00.0
081.00.00.00.0
090.00.00.01.0
100.0010.8630.00.135
110.0510.0650.8350.049
120.4510.1150.3280.106
130.1450.1930.1850.476
PWM
ACGT
01-0.041-0.020.189-0.16
02-0.734-0.3990.2490.449
03-1.053-2.505-1.1451.179
041.386-6.941-6.941-6.941
05-6.941-6.941-6.9411.386
06-6.9411.381-6.941-3.978
07-6.941-6.9411.386-6.941
081.386-6.941-6.941-6.941
09-6.941-5.93-6.9411.385
10-5.2611.239-5.93-0.615
11-1.589-1.3491.205-1.62
120.59-0.780.273-0.858
13-0.542-0.258-0.2990.644
Standard thresholds
P-value Threshold
0.001 -0.85723
0.0005 0.86357
0.0001 5.00828