Motif | ONEC2.H12CORE.1.PM.A |
Gene (human) | ONECUT2 (GeneCards) |
Gene synonyms (human) | HNF6B |
Gene (mouse) | Onecut2 |
Gene synonyms (mouse) | Oc2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif | ONEC2.H12CORE.1.PM.A |
Gene (human) | ONECUT2 (GeneCards) |
Gene synonyms (human) | HNF6B |
Gene (mouse) | Onecut2 |
Gene synonyms (mouse) | Oc2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif length | 13 |
Consensus | nbTATTGATYddb |
GC content | 28.63% |
Information content (bits; total / per base) | 15.55 / 1.196 |
Data sources | ChIP-Seq + Methyl-HT-SELEX |
Aligned words | 2353 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 4 (22) | 0.811 | 0.931 | 0.704 | 0.894 | 0.798 | 0.863 | 2.746 | 3.215 | 51.255 | 220.013 |
Mouse | 2 (12) | 0.977 | 0.988 | 0.95 | 0.971 | 0.924 | 0.949 | 4.086 | 4.338 | 536.594 | 622.678 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.987 | 0.977 | 0.961 | 0.938 | 0.908 | 0.893 |
best | 0.998 | 0.997 | 0.998 | 0.996 | 0.997 | 0.994 | |
Methyl HT-SELEX, 3 experiments | median | 0.998 | 0.996 | 0.997 | 0.995 | 0.996 | 0.994 |
best | 0.998 | 0.997 | 0.998 | 0.996 | 0.997 | 0.994 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.96 | 0.932 | 0.937 | 0.905 | 0.831 | 0.815 |
best | 0.993 | 0.988 | 0.992 | 0.986 | 0.992 | 0.985 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HD-CUT {3.1.9} (TFClass) |
TF subfamily | ONECUT {3.1.9.1} (TFClass) |
TFClass ID | TFClass: 3.1.9.1.2 |
HGNC | HGNC:8139 |
MGI | MGI:1891408 |
EntrezGene (human) | GeneID:9480 (SSTAR profile) |
EntrezGene (mouse) | GeneID:225631 (SSTAR profile) |
UniProt ID (human) | ONEC2_HUMAN |
UniProt ID (mouse) | ONEC2_MOUSE |
UniProt AC (human) | O95948 (TFClass) |
UniProt AC (mouse) | Q6XBJ3 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 4 human, 2 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 3 |
PCM | ONEC2.H12CORE.1.PM.A.pcm |
PWM | ONEC2.H12CORE.1.PM.A.pwm |
PFM | ONEC2.H12CORE.1.PM.A.pfm |
Alignment | ONEC2.H12CORE.1.PM.A.words.tsv |
Threshold to P-value map | ONEC2.H12CORE.1.PM.A.thr |
Motif in other formats | |
JASPAR format | ONEC2.H12CORE.1.PM.A_jaspar_format.txt |
MEME format | ONEC2.H12CORE.1.PM.A_meme_format.meme |
Transfac format | ONEC2.H12CORE.1.PM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 693.25 | 488.25 | 646.25 | 525.25 |
02 | 254.0 | 262.0 | 867.0 | 970.0 |
03 | 26.0 | 47.0 | 66.0 | 2214.0 |
04 | 2353.0 | 0.0 | 0.0 | 0.0 |
05 | 0.0 | 0.0 | 0.0 | 2353.0 |
06 | 0.0 | 31.0 | 0.0 | 2322.0 |
07 | 0.0 | 0.0 | 2353.0 | 0.0 |
08 | 2353.0 | 0.0 | 0.0 | 0.0 |
09 | 0.0 | 8.0 | 1.0 | 2344.0 |
10 | 5.0 | 949.0 | 3.0 | 1396.0 |
11 | 590.0 | 143.0 | 1269.0 | 351.0 |
12 | 1215.25 | 256.25 | 515.25 | 366.25 |
13 | 311.75 | 456.75 | 396.75 | 1187.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.295 | 0.208 | 0.275 | 0.223 |
02 | 0.108 | 0.111 | 0.368 | 0.412 |
03 | 0.011 | 0.02 | 0.028 | 0.941 |
04 | 1.0 | 0.0 | 0.0 | 0.0 |
05 | 0.0 | 0.0 | 0.0 | 1.0 |
06 | 0.0 | 0.013 | 0.0 | 0.987 |
07 | 0.0 | 0.0 | 1.0 | 0.0 |
08 | 1.0 | 0.0 | 0.0 | 0.0 |
09 | 0.0 | 0.003 | 0.0 | 0.996 |
10 | 0.002 | 0.403 | 0.001 | 0.593 |
11 | 0.251 | 0.061 | 0.539 | 0.149 |
12 | 0.516 | 0.109 | 0.219 | 0.156 |
13 | 0.132 | 0.194 | 0.169 | 0.505 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.164 | -0.186 | 0.094 | -0.113 |
02 | -0.835 | -0.805 | 0.387 | 0.499 |
03 | -3.05 | -2.49 | -2.162 | 1.323 |
04 | 1.384 | -5.717 | -5.717 | -5.717 |
05 | -5.717 | -5.717 | -5.717 | 1.384 |
06 | -5.717 | -2.886 | -5.717 | 1.371 |
07 | -5.717 | -5.717 | 1.384 | -5.717 |
08 | 1.384 | -5.717 | -5.717 | -5.717 |
09 | -5.717 | -4.084 | -5.302 | 1.38 |
10 | -4.443 | 0.477 | -4.783 | 0.862 |
11 | 0.003 | -1.404 | 0.767 | -0.514 |
12 | 0.724 | -0.827 | -0.132 | -0.472 |
13 | -0.632 | -0.252 | -0.392 | 0.701 |
P-value | Threshold |
---|---|
0.001 | 0.38366 |
0.0005 | 2.31353 |
0.0001 | 5.559125 |