MotifONEC2.H12CORE.0.S.B
Gene (human)ONECUT2
(GeneCards)
Gene synonyms (human)HNF6B
Gene (mouse)Onecut2
Gene synonyms (mouse)Oc2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusndTATCGATYdn
GC content33.35%
Information content (bits; total / per base)13.387 / 1.116
Data sourcesHT-SELEX
Aligned words8132

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (22) 0.83 0.941 0.743 0.913 0.826 0.908 2.706 3.37 60.293 182.602
Mouse 2 (12) 0.984 0.99 0.956 0.967 0.948 0.952 3.489 3.546 587.733 671.18

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.986 0.974 0.978 0.964 0.915 0.911
best 0.998 0.997 0.998 0.997 0.998 0.996
Methyl HT-SELEX, 3 experiments median 0.99 0.98 0.991 0.981 0.992 0.983
best 0.993 0.986 0.994 0.988 0.994 0.988
Non-Methyl HT-SELEX, 5 experiments median 0.983 0.968 0.964 0.947 0.838 0.839
best 0.998 0.997 0.998 0.997 0.998 0.996
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyONECUT {3.1.9.1} (TFClass)
TFClass IDTFClass: 3.1.9.1.2
HGNCHGNC:8139
MGIMGI:1891408
EntrezGene (human)GeneID:9480
(SSTAR profile)
EntrezGene (mouse)GeneID:225631
(SSTAR profile)
UniProt ID (human)ONEC2_HUMAN
UniProt ID (mouse)ONEC2_MOUSE
UniProt AC (human)O95948
(TFClass)
UniProt AC (mouse)Q6XBJ3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 2 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
012953.51093.52096.51988.5
021917.25752.251627.253835.25
03599.0502.0440.06591.0
047974.048.026.084.0
051.04.05.08122.0
060.07441.00.0691.0
074.02.08126.00.0
088116.010.05.01.0
09107.0199.065.07761.0
1055.03411.0107.04559.0
111428.51192.52133.53377.5
121765.01552.01707.03108.0
PFM
ACGT
010.3630.1340.2580.245
020.2360.0930.20.472
030.0740.0620.0540.811
040.9810.0060.0030.01
050.00.00.0010.999
060.00.9150.00.085
070.00.00.9990.0
080.9980.0010.0010.0
090.0130.0240.0080.954
100.0070.4190.0130.561
110.1760.1470.2620.415
120.2170.1910.210.382
PWM
ACGT
010.373-0.6190.031-0.022
02-0.059-0.992-0.2220.634
03-1.219-1.395-1.5261.175
041.366-3.701-4.277-3.161
05-6.439-5.786-5.6371.384
06-6.8071.297-6.807-1.077
07-5.786-6.1711.385-6.807
081.383-5.113-5.637-6.439
09-2.925-2.314-3.411.339
10-3.5710.517-2.9250.807
11-0.352-0.5330.0480.507
12-0.141-0.27-0.1750.424
Standard thresholds
P-value Threshold
0.001 2.650615
0.0005 3.99846
0.0001 7.094075