Motif | ONEC2.H12CORE.0.S.B |
Gene (human) | ONECUT2 (GeneCards) |
Gene synonyms (human) | HNF6B |
Gene (mouse) | Onecut2 |
Gene synonyms (mouse) | Oc2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | ONEC2.H12CORE.0.S.B |
Gene (human) | ONECUT2 (GeneCards) |
Gene synonyms (human) | HNF6B |
Gene (mouse) | Onecut2 |
Gene synonyms (mouse) | Oc2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 12 |
Consensus | ndTATCGATYdn |
GC content | 33.35% |
Information content (bits; total / per base) | 13.387 / 1.116 |
Data sources | HT-SELEX |
Aligned words | 8132 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 4 (22) | 0.83 | 0.941 | 0.743 | 0.913 | 0.826 | 0.908 | 2.706 | 3.37 | 60.293 | 182.602 |
Mouse | 2 (12) | 0.984 | 0.99 | 0.956 | 0.967 | 0.948 | 0.952 | 3.489 | 3.546 | 587.733 | 671.18 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.986 | 0.974 | 0.978 | 0.964 | 0.915 | 0.911 |
best | 0.998 | 0.997 | 0.998 | 0.997 | 0.998 | 0.996 | |
Methyl HT-SELEX, 3 experiments | median | 0.99 | 0.98 | 0.991 | 0.981 | 0.992 | 0.983 |
best | 0.993 | 0.986 | 0.994 | 0.988 | 0.994 | 0.988 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.983 | 0.968 | 0.964 | 0.947 | 0.838 | 0.839 |
best | 0.998 | 0.997 | 0.998 | 0.997 | 0.998 | 0.996 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HD-CUT {3.1.9} (TFClass) |
TF subfamily | ONECUT {3.1.9.1} (TFClass) |
TFClass ID | TFClass: 3.1.9.1.2 |
HGNC | HGNC:8139 |
MGI | MGI:1891408 |
EntrezGene (human) | GeneID:9480 (SSTAR profile) |
EntrezGene (mouse) | GeneID:225631 (SSTAR profile) |
UniProt ID (human) | ONEC2_HUMAN |
UniProt ID (mouse) | ONEC2_MOUSE |
UniProt AC (human) | O95948 (TFClass) |
UniProt AC (mouse) | Q6XBJ3 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 4 human, 2 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 3 |
PCM | ONEC2.H12CORE.0.S.B.pcm |
PWM | ONEC2.H12CORE.0.S.B.pwm |
PFM | ONEC2.H12CORE.0.S.B.pfm |
Alignment | ONEC2.H12CORE.0.S.B.words.tsv |
Threshold to P-value map | ONEC2.H12CORE.0.S.B.thr |
Motif in other formats | |
JASPAR format | ONEC2.H12CORE.0.S.B_jaspar_format.txt |
MEME format | ONEC2.H12CORE.0.S.B_meme_format.meme |
Transfac format | ONEC2.H12CORE.0.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2953.5 | 1093.5 | 2096.5 | 1988.5 |
02 | 1917.25 | 752.25 | 1627.25 | 3835.25 |
03 | 599.0 | 502.0 | 440.0 | 6591.0 |
04 | 7974.0 | 48.0 | 26.0 | 84.0 |
05 | 1.0 | 4.0 | 5.0 | 8122.0 |
06 | 0.0 | 7441.0 | 0.0 | 691.0 |
07 | 4.0 | 2.0 | 8126.0 | 0.0 |
08 | 8116.0 | 10.0 | 5.0 | 1.0 |
09 | 107.0 | 199.0 | 65.0 | 7761.0 |
10 | 55.0 | 3411.0 | 107.0 | 4559.0 |
11 | 1428.5 | 1192.5 | 2133.5 | 3377.5 |
12 | 1765.0 | 1552.0 | 1707.0 | 3108.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.363 | 0.134 | 0.258 | 0.245 |
02 | 0.236 | 0.093 | 0.2 | 0.472 |
03 | 0.074 | 0.062 | 0.054 | 0.811 |
04 | 0.981 | 0.006 | 0.003 | 0.01 |
05 | 0.0 | 0.0 | 0.001 | 0.999 |
06 | 0.0 | 0.915 | 0.0 | 0.085 |
07 | 0.0 | 0.0 | 0.999 | 0.0 |
08 | 0.998 | 0.001 | 0.001 | 0.0 |
09 | 0.013 | 0.024 | 0.008 | 0.954 |
10 | 0.007 | 0.419 | 0.013 | 0.561 |
11 | 0.176 | 0.147 | 0.262 | 0.415 |
12 | 0.217 | 0.191 | 0.21 | 0.382 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.373 | -0.619 | 0.031 | -0.022 |
02 | -0.059 | -0.992 | -0.222 | 0.634 |
03 | -1.219 | -1.395 | -1.526 | 1.175 |
04 | 1.366 | -3.701 | -4.277 | -3.161 |
05 | -6.439 | -5.786 | -5.637 | 1.384 |
06 | -6.807 | 1.297 | -6.807 | -1.077 |
07 | -5.786 | -6.171 | 1.385 | -6.807 |
08 | 1.383 | -5.113 | -5.637 | -6.439 |
09 | -2.925 | -2.314 | -3.41 | 1.339 |
10 | -3.571 | 0.517 | -2.925 | 0.807 |
11 | -0.352 | -0.533 | 0.048 | 0.507 |
12 | -0.141 | -0.27 | -0.175 | 0.424 |
P-value | Threshold |
---|---|
0.001 | 2.650615 |
0.0005 | 3.99846 |
0.0001 | 7.094075 |