OLIG3.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	OLIG3.H12INVITRO.0.SM.B
Gene (human)	OLIG3 (GeneCards)
Gene synonyms (human)	BHLHB7, BHLHE20
Gene (mouse)	Olig3
Gene synonyms (mouse)	Bhlhb7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	nSCATATGKTn
GC content	39.11%
Information content (bits; total / per base)	14.027 / 1.275
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2499

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.996	0.994	0.975	0.971	0.829	0.843
Overall, 8 experiments	best	0.999	0.999	0.999	0.999	0.985	0.984
Methyl HT-SELEX, 3 experiments	median	0.999	0.999	0.981	0.98	0.849	0.851
Methyl HT-SELEX, 3 experiments	best	0.999	0.999	0.999	0.999	0.985	0.984
Non-Methyl HT-SELEX, 5 experiments	median	0.977	0.967	0.912	0.896	0.79	0.785
Non-Methyl HT-SELEX, 5 experiments	best	0.999	0.998	0.998	0.997	0.972	0.971

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.931	0.751	0.91	0.581
batch 2	0.987	0.835	0.917	0.581

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	Neurogenin-ATO {1.2.3.4} (TFClass)
TFClass ID	TFClass: 1.2.3.4.15
HGNC	HGNC:18003
MGI	MGI:2149955
EntrezGene (human)	GeneID:167826 (SSTAR profile)
EntrezGene (mouse)	GeneID:94222 (SSTAR profile)
UniProt ID (human)	OLIG3_HUMAN
UniProt ID (mouse)	OLIG3_MOUSE
UniProt AC (human)	Q7RTU3 (TFClass)
UniProt AC (mouse)	Q6PFG8 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	3

PCM	OLIG3.H12INVITRO.0.SM.B.pcm
PWM	OLIG3.H12INVITRO.0.SM.B.pwm
PFM	OLIG3.H12INVITRO.0.SM.B.pfm
Alignment	OLIG3.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	OLIG3.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	OLIG3.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	OLIG3.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	OLIG3.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	OLIG3.H12INVITRO.0.SM.B_homer_format_0.001.txt OLIG3.H12INVITRO.0.SM.B_homer_format_0.0005.txt OLIG3.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	975.0	430.0	618.0	476.0
02	404.5	1481.5	507.5	105.5
03	110.0	2385.0	3.0	1.0
04	2428.0	1.0	66.0	4.0
05	0.0	1.0	9.0	2489.0
06	2494.0	4.0	1.0	0.0
07	0.0	0.0	0.0	2499.0
08	0.0	1.0	2498.0	0.0
09	0.0	137.0	1269.0	1093.0
10	96.0	185.0	56.0	2162.0
11	543.5	596.5	500.5	858.5

PFM

	A	C	G	T
01	0.39	0.172	0.247	0.19
02	0.162	0.593	0.203	0.042
03	0.044	0.954	0.001	0.0
04	0.972	0.0	0.026	0.002
05	0.0	0.0	0.004	0.996
06	0.998	0.002	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	1.0	0.0
09	0.0	0.055	0.508	0.437
10	0.038	0.074	0.022	0.865
11	0.217	0.239	0.2	0.344

PWM

	A	C	G	T
01	0.444	-0.372	-0.011	-0.271
02	-0.433	0.862	-0.207	-1.763
03	-1.722	1.337	-4.84	-5.357
04	1.355	-5.357	-2.222	-4.656
05	-5.77	-5.357	-4.047	1.38
06	1.382	-4.656	-5.357	-5.77
07	-5.77	-5.77	-5.77	1.384
08	-5.77	-5.357	1.384	-5.77
09	-5.77	-1.506	0.707	0.558
10	-1.856	-1.21	-2.381	1.239
11	-0.139	-0.046	-0.221	0.317

Standard thresholds

P-value	Threshold
0.001	1.997515
0.0005	3.5435
0.0001	6.87756