OLIG3.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	OLIG3.H12CORE.0.SM.B
Gene (human)	OLIG3 (GeneCards)
Gene synonyms (human)	BHLHB7, BHLHE20
Gene (mouse)	Olig3
Gene synonyms (mouse)	Bhlhb7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nRCCATATGTTbn
GC content	39.73%
Information content (bits; total / per base)	17.361 / 1.335
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	7969

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.996	0.994	0.969	0.964	0.817	0.832
Overall, 8 experiments	best	1.0	0.999	0.998	0.997	0.965	0.964
Methyl HT-SELEX, 3 experiments	median	0.999	0.999	0.977	0.976	0.834	0.838
Methyl HT-SELEX, 3 experiments	best	1.0	0.999	0.998	0.997	0.919	0.925
Non-Methyl HT-SELEX, 5 experiments	median	0.946	0.936	0.815	0.798	0.701	0.7
Non-Methyl HT-SELEX, 5 experiments	best	0.999	0.998	0.998	0.997	0.965	0.964

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.945	0.844	0.929	0.626
batch 2	0.995	0.922	0.936	0.729

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	Neurogenin-ATO {1.2.3.4} (TFClass)
TFClass ID	TFClass: 1.2.3.4.15
HGNC	HGNC:18003
MGI	MGI:2149955
EntrezGene (human)	GeneID:167826 (SSTAR profile)
EntrezGene (mouse)	GeneID:94222 (SSTAR profile)
UniProt ID (human)	OLIG3_HUMAN
UniProt ID (mouse)	OLIG3_MOUSE
UniProt AC (human)	Q7RTU3 (TFClass)
UniProt AC (mouse)	Q6PFG8 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	3

PCM	OLIG3.H12CORE.0.SM.B.pcm
PWM	OLIG3.H12CORE.0.SM.B.pwm
PFM	OLIG3.H12CORE.0.SM.B.pfm
Alignment	OLIG3.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	OLIG3.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	OLIG3.H12CORE.0.SM.B_jaspar_format.txt
MEME format	OLIG3.H12CORE.0.SM.B_meme_format.meme
Transfac format	OLIG3.H12CORE.0.SM.B_transfac_format.txt
Homer format	OLIG3.H12CORE.0.SM.B_homer_format_0.001.txt OLIG3.H12CORE.0.SM.B_homer_format_0.0005.txt OLIG3.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1724.0	2540.0	1953.0	1752.0
02	5441.25	141.25	2022.25	364.25
03	1023.0	6596.0	350.0	0.0
04	0.0	7969.0	0.0	0.0
05	7969.0	0.0	0.0	0.0
06	0.0	0.0	0.0	7969.0
07	7969.0	0.0	0.0	0.0
08	0.0	0.0	0.0	7969.0
09	0.0	0.0	7969.0	0.0
10	0.0	0.0	3115.0	4854.0
11	0.0	4.0	0.0	7965.0
12	612.0	3064.0	1079.0	3214.0
13	1446.5	2624.5	1731.5	2166.5

PFM

	A	C	G	T
01	0.216	0.319	0.245	0.22
02	0.683	0.018	0.254	0.046
03	0.128	0.828	0.044	0.0
04	0.0	1.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	0.0	0.0	1.0
07	1.0	0.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.0	1.0	0.0
10	0.0	0.0	0.391	0.609
11	0.0	0.001	0.0	0.999
12	0.077	0.384	0.135	0.403
13	0.182	0.329	0.217	0.272

PWM

	A	C	G	T
01	-0.144	0.243	-0.02	-0.128
02	1.004	-2.632	0.015	-1.694
03	-0.665	1.196	-1.734	-6.789
04	-6.789	1.385	-6.789	-6.789
05	1.385	-6.789	-6.789	-6.789
06	-6.789	-6.789	-6.789	1.385
07	1.385	-6.789	-6.789	-6.789
08	-6.789	-6.789	-6.789	1.385
09	-6.789	-6.789	1.385	-6.789
10	-6.789	-6.789	0.447	0.89
11	-6.789	-5.766	-6.789	1.385
12	-1.178	0.43	-0.612	0.478
13	-0.32	0.275	-0.14	0.084

Standard thresholds

P-value	Threshold
0.001	-4.380695
0.0005	-2.1492
0.0001	3.062095