| Motif | OLIG2.H12RSNP.0.P.B |
| Gene (human) | OLIG2 (GeneCards) |
| Gene synonyms (human) | BHLHB1, BHLHE19, PRKCBP2, RACK17 |
| Gene (mouse) | Olig2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | OLIG2.H12RSNP.0.P.B |
| Gene (human) | OLIG2 (GeneCards) |
| Gene synonyms (human) | BHLHB1, BHLHE19, PRKCBP2, RACK17 |
| Gene (mouse) | Olig2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 17 |
| Consensus | nbnnnSCAGCTGbYbbh |
| GC content | 57.82% |
| Information content (bits; total / per base) | 10.42 / 0.613 |
| Data sources | ChIP-Seq |
| Aligned words | 961 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 8 (40) | 0.744 | 0.805 | 0.609 | 0.678 | 0.692 | 0.738 | 2.004 | 2.218 | 42.246 | 98.553 |
| Mouse | 9 (60) | 0.843 | 0.888 | 0.715 | 0.77 | 0.759 | 0.835 | 2.194 | 2.632 | 111.155 | 184.658 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.778 | 0.716 | 0.684 | 0.65 | 0.611 | 0.6 |
| best | 0.915 | 0.853 | 0.874 | 0.82 | 0.762 | 0.738 | |
| Methyl HT-SELEX, 2 experiments | median | 0.901 | 0.839 | 0.852 | 0.798 | 0.754 | 0.724 |
| best | 0.915 | 0.853 | 0.874 | 0.82 | 0.762 | 0.738 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.694 | 0.639 | 0.632 | 0.599 | 0.58 | 0.569 |
| best | 0.869 | 0.798 | 0.806 | 0.75 | 0.709 | 0.681 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 8.043 | 5.235 | 0.385 | 0.213 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.883 | 0.25 | 0.863 | 0.59 |
| batch 2 | 0.599 | 0.32 | 0.567 | 0.378 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | Tal-related {1.2.3} (TFClass) |
| TF subfamily | Neurogenin-ATO {1.2.3.4} (TFClass) |
| TFClass ID | TFClass: 1.2.3.4.14 |
| HGNC | HGNC:9398 |
| MGI | MGI:1355331 |
| EntrezGene (human) | GeneID:10215 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:50913 (SSTAR profile) |
| UniProt ID (human) | OLIG2_HUMAN |
| UniProt ID (mouse) | OLIG2_MOUSE |
| UniProt AC (human) | Q13516 (TFClass) |
| UniProt AC (mouse) | Q9EQW6 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 8 human, 9 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | OLIG2.H12RSNP.0.P.B.pcm |
| PWM | OLIG2.H12RSNP.0.P.B.pwm |
| PFM | OLIG2.H12RSNP.0.P.B.pfm |
| Alignment | OLIG2.H12RSNP.0.P.B.words.tsv |
| Threshold to P-value map | OLIG2.H12RSNP.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | OLIG2.H12RSNP.0.P.B_jaspar_format.txt |
| MEME format | OLIG2.H12RSNP.0.P.B_meme_format.meme |
| Transfac format | OLIG2.H12RSNP.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 130.0 | 253.0 | 336.0 | 242.0 |
| 02 | 120.0 | 386.0 | 265.0 | 190.0 |
| 03 | 246.0 | 331.0 | 135.0 | 249.0 |
| 04 | 135.0 | 299.0 | 254.0 | 273.0 |
| 05 | 221.0 | 229.0 | 283.0 | 228.0 |
| 06 | 143.0 | 518.0 | 280.0 | 20.0 |
| 07 | 159.0 | 790.0 | 6.0 | 6.0 |
| 08 | 850.0 | 19.0 | 18.0 | 74.0 |
| 09 | 6.0 | 10.0 | 728.0 | 217.0 |
| 10 | 176.0 | 758.0 | 6.0 | 21.0 |
| 11 | 24.0 | 28.0 | 5.0 | 904.0 |
| 12 | 2.0 | 13.0 | 910.0 | 36.0 |
| 13 | 43.0 | 267.0 | 217.0 | 434.0 |
| 14 | 21.0 | 185.0 | 176.0 | 579.0 |
| 15 | 84.0 | 260.0 | 247.0 | 370.0 |
| 16 | 68.0 | 478.0 | 188.0 | 227.0 |
| 17 | 97.0 | 486.0 | 82.0 | 296.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.135 | 0.263 | 0.35 | 0.252 |
| 02 | 0.125 | 0.402 | 0.276 | 0.198 |
| 03 | 0.256 | 0.344 | 0.14 | 0.259 |
| 04 | 0.14 | 0.311 | 0.264 | 0.284 |
| 05 | 0.23 | 0.238 | 0.294 | 0.237 |
| 06 | 0.149 | 0.539 | 0.291 | 0.021 |
| 07 | 0.165 | 0.822 | 0.006 | 0.006 |
| 08 | 0.884 | 0.02 | 0.019 | 0.077 |
| 09 | 0.006 | 0.01 | 0.758 | 0.226 |
| 10 | 0.183 | 0.789 | 0.006 | 0.022 |
| 11 | 0.025 | 0.029 | 0.005 | 0.941 |
| 12 | 0.002 | 0.014 | 0.947 | 0.037 |
| 13 | 0.045 | 0.278 | 0.226 | 0.452 |
| 14 | 0.022 | 0.193 | 0.183 | 0.602 |
| 15 | 0.087 | 0.271 | 0.257 | 0.385 |
| 16 | 0.071 | 0.497 | 0.196 | 0.236 |
| 17 | 0.101 | 0.506 | 0.085 | 0.308 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.608 | 0.051 | 0.333 | 0.007 |
| 02 | -0.687 | 0.471 | 0.097 | -0.233 |
| 03 | 0.023 | 0.318 | -0.571 | 0.036 |
| 04 | -0.571 | 0.217 | 0.055 | 0.127 |
| 05 | -0.083 | -0.048 | 0.163 | -0.052 |
| 06 | -0.514 | 0.764 | 0.152 | -2.411 |
| 07 | -0.409 | 1.185 | -3.445 | -3.445 |
| 08 | 1.258 | -2.458 | -2.507 | -1.162 |
| 09 | -3.445 | -3.028 | 1.104 | -0.101 |
| 10 | -0.309 | 1.144 | -3.445 | -2.366 |
| 11 | -2.242 | -2.097 | -3.584 | 1.32 |
| 12 | -4.176 | -2.8 | 1.327 | -1.859 |
| 13 | -1.688 | 0.105 | -0.101 | 0.588 |
| 14 | -2.366 | -0.259 | -0.309 | 0.875 |
| 15 | -1.038 | 0.078 | 0.028 | 0.429 |
| 16 | -1.244 | 0.684 | -0.243 | -0.056 |
| 17 | -0.897 | 0.701 | -1.061 | 0.207 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.64181 |
| 0.0005 | 5.52576 |
| 0.0001 | 7.32976 |