MotifOLIG2.H12INVITRO.2.SM.B
Gene (human)OLIG2
(GeneCards)
Gene synonyms (human)BHLHB1, BHLHE19, PRKCBP2, RACK17
Gene (mouse)Olig2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length11
ConsensusnvCATATGKYn
GC content36.75%
Information content (bits; total / per base)11.256 / 1.023
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9325

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (40) 0.627 0.693 0.447 0.537 0.559 0.648 1.333 1.672 15.503 65.921
Mouse 9 (60) 0.698 0.751 0.517 0.585 0.725 0.799 2.019 2.494 68.688 123.398

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.92 0.894 0.788 0.774 0.681 0.683
best 0.998 0.996 0.986 0.982 0.892 0.892
Methyl HT-SELEX, 2 experiments median 0.988 0.981 0.965 0.953 0.875 0.866
best 0.998 0.996 0.986 0.982 0.892 0.892
Non-Methyl HT-SELEX, 6 experiments median 0.817 0.786 0.702 0.7 0.608 0.625
best 0.99 0.985 0.958 0.946 0.86 0.852

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.5 1.494 0.331 0.144

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.924 0.595 0.903 0.59
batch 2 0.659 0.413 0.628 0.471
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyNeurogenin-ATO {1.2.3.4} (TFClass)
TFClass IDTFClass: 1.2.3.4.14
HGNCHGNC:9398
MGIMGI:1355331
EntrezGene (human)GeneID:10215
(SSTAR profile)
EntrezGene (mouse)GeneID:50913
(SSTAR profile)
UniProt ID (human)OLIG2_HUMAN
UniProt ID (mouse)OLIG2_MOUSE
UniProt AC (human)Q13516
(TFClass)
UniProt AC (mouse)Q9EQW6
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 9 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
013166.751539.752251.752366.75
022085.754960.751301.75976.75
032084.06997.0180.064.0
048338.021.0517.0449.0
052.0170.0556.08597.0
068827.0476.022.00.0
0757.0238.02.09028.0
080.01.09314.010.0
0934.01259.02801.05231.0
10695.75956.75537.757134.75
112486.51936.51652.53249.5
PFM
ACGT
010.340.1650.2410.254
020.2240.5320.140.105
030.2230.750.0190.007
040.8940.0020.0550.048
050.00.0180.060.922
060.9470.0510.0020.0
070.0060.0260.00.968
080.00.00.9990.001
090.0040.1350.30.561
100.0750.1030.0580.765
110.2670.2080.1770.348
PWM
ACGT
010.306-0.414-0.0350.015
02-0.1110.755-0.582-0.869
03-0.1121.098-2.55-3.561
041.274-4.607-1.503-1.643
05-6.3-2.606-1.431.304
061.331-1.585-4.565-6.929
07-3.673-2.273-6.31.353
08-6.929-6.5661.384-5.247
09-4.164-0.6150.1830.808
10-1.207-0.889-1.4641.118
110.064-0.185-0.3440.332
Standard thresholds
P-value Threshold
0.001 4.305875
0.0005 5.41425
0.0001 7.42118