NRF1.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NRF1.H12INVIVO.0.PS.A
Gene (human)	NRF1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Nrf1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	bnbYGCGCAKGCGCvn
GC content	68.7%
Information content (bits; total / per base)	17.098 / 1.069
Data sources	ChIP-Seq + HT-SELEX
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	20 (135)	0.987	0.995	0.964	0.984	0.986	0.996	6.148	6.794	483.585	751.377
Mouse	14 (87)	0.987	0.996	0.967	0.992	0.986	0.993	6.129	6.622	506.092	827.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.856	0.857	0.736	0.745	0.628	0.65
Non-Methyl HT-SELEX, 2 experiments	best	1.0	1.0	0.854	0.869	0.686	0.725

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.067	7.55	0.152	0.102

TF superclass	Yet undefined DNA-binding domains {0} (TFClass)
TF class	Uncharacterized {0.0} (TFClass)
TF family	NRF {0.0.6} (TFClass)
TF subfamily	{0.0.6.0} (TFClass)
TFClass ID	TFClass: 0.0.6.0.1
HGNC	HGNC:7996
MGI	MGI:1332235
EntrezGene (human)	GeneID:4899 (SSTAR profile)
EntrezGene (mouse)	GeneID:18181 (SSTAR profile)
UniProt ID (human)	NRF1_HUMAN
UniProt ID (mouse)	NRF1_MOUSE
UniProt AC (human)	Q16656 (TFClass)
UniProt AC (mouse)	Q9WU00 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	20 human, 14 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	NRF1.H12INVIVO.0.PS.A.pcm
PWM	NRF1.H12INVIVO.0.PS.A.pwm
PFM	NRF1.H12INVIVO.0.PS.A.pfm
Alignment	NRF1.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	NRF1.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	NRF1.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	NRF1.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	NRF1.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	NRF1.H12INVIVO.0.PS.A_homer_format_0.001.txt NRF1.H12INVIVO.0.PS.A_homer_format_0.0005.txt NRF1.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	128.0	442.0	196.0	231.0
02	283.0	264.0	231.0	219.0
03	94.0	453.0	281.0	169.0
04	33.0	141.0	43.0	780.0
05	81.0	0.0	916.0	0.0
06	1.0	993.0	1.0	2.0
07	3.0	0.0	994.0	0.0
08	0.0	997.0	0.0	0.0
09	994.0	1.0	1.0	1.0
10	62.0	103.0	292.0	540.0
11	14.0	20.0	955.0	8.0
12	16.0	899.0	5.0	77.0
13	4.0	35.0	846.0	112.0
14	4.0	802.0	15.0	176.0
15	487.0	184.0	223.0	103.0
16	183.0	228.0	398.0	188.0

PFM

	A	C	G	T
01	0.128	0.443	0.197	0.232
02	0.284	0.265	0.232	0.22
03	0.094	0.454	0.282	0.17
04	0.033	0.141	0.043	0.782
05	0.081	0.0	0.919	0.0
06	0.001	0.996	0.001	0.002
07	0.003	0.0	0.997	0.0
08	0.0	1.0	0.0	0.0
09	0.997	0.001	0.001	0.001
10	0.062	0.103	0.293	0.542
11	0.014	0.02	0.958	0.008
12	0.016	0.902	0.005	0.077
13	0.004	0.035	0.849	0.112
14	0.004	0.804	0.015	0.177
15	0.488	0.185	0.224	0.103
16	0.184	0.229	0.399	0.189

PWM

	A	C	G	T
01	-0.66	0.57	-0.238	-0.075
02	0.126	0.057	-0.075	-0.128
03	-0.964	0.594	0.119	-0.385
04	-1.978	-0.564	-1.725	1.136
05	-1.11	-4.979	1.297	-4.979
06	-4.522	1.377	-4.522	-4.21
07	-3.972	-4.979	1.378	-4.979
08	-4.979	1.381	-4.979	-4.979
09	1.378	-4.522	-4.522	-4.522
10	-1.371	-0.874	0.157	0.769
11	-2.77	-2.447	1.338	-3.251
12	-2.65	1.278	-3.619	-1.159
13	-3.78	-1.922	1.217	-0.792
14	-3.78	1.164	-2.708	-0.345
15	0.666	-0.301	-0.11	-0.874
16	-0.306	-0.088	0.465	-0.28

Standard thresholds

P-value	Threshold
0.001	1.07366
0.0005	2.55326
0.0001	5.63326